Drug
Diclofenac clinical trials
Also written Voltaren, Cataflam and XP21L.
Includes 1 study of Diclofenac etalhyaluronate.
- studies test it
- 210
- open now
- 16
- in phase 3
- 50
- first study started
- 1993
Keep track of what changes. Save the Diclofenac studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Other names
Combined with it in one product
Studies by the year they started
209 studies that test it; most in 2015 (20)
| Year | Studies |
|---|---|
| 1993 | 2 |
| 1994 | 1 |
| 1997 | 1 |
| 2000 | 3 |
| 2002 | 4 |
| 2003 | 3 |
| 2004 | 5 |
| 2005 | 4 |
| 2006 | 8 |
| 2007 | 8 |
| 2008 | 8 |
| 2009 | 6 |
| 2010 | 6 |
| 2011 | 14 |
| 2012 | 10 |
| 2013 | 8 |
| 2014 | 7 |
| 2015 | 20 |
| 2016 | 13 |
| 2017 | 10 |
| 2018 | 8 |
| 2019 | 2 |
| 2020 | 4 |
| 2021 | 10 |
| 2022 | 9 |
| 2023 | 6 |
| 2024 | 15 |
| 2025 | 10 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 6
- Phase 1
- 29
- Phase 2
- 37
- Phase 3
- 50
- Phase 4
- 60
- No phase
- 43
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 75 · Other 135
Cairo University (17) · Pfizer (6) · Assiut University (6) · Novartis (5) · Cerimon Pharmaceuticals (5) · Javelin Pharmaceuticals (5) · Hamad Medical Corporation (4) · Novartis Pharmaceuticals (4)
Often tested with
Tested in the same studies.
Tramadol (12) · Acetaminophen (11) · Ibuprofen (10) · Lidocaine (9) · Ketorolac (5) · Valdecoxib (4) · Water (3) · Bromfenac (3)
Studies
Open first, then newest update. How each study uses Diclofenac is read from its arms, and is right about nine times in ten.
Testing it · 210
- Medication vs. Meditation for Chronic Knee OsteoarthritisNot yet recruitingEarly Phase 1Florida State UniversityNCT07837284Written as Oral diclofenac potassium 50 mg
- NonNarcotic Pain Control in Percutaneous Needle Tenotomy of ElbowRecruitingPhase 4The Cleveland ClinicNCT06373978Written as Diclofenac
- Holistic Healing for Knee OsteoarthritisNot yet recruitingNot applicableAll India Institute of Medical Sciences, JodhpurNCT07768709Written as Topical Diclofenac Spray
- Effect of Preoperative Diclofenac Potassium Dose on Endodontic PainNot yet recruitingNot applicableCairo UniversityNCT07743372Written as Diclofenac potassium 100mg
- The Effects of Patient and Visit Characteristics on Health Outcomes in Knee OsteoarthritisRecruitingNot applicableUniversity of California, DavisNCT06574191Written as Topical Diclofenac gel 1%
- Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent ImmunotherapyRecruitingPhase 2Emory UniversityNCT06731270Written as Diclofenac Potassium
- Comparing Efficacy of Bromfenac 0.09%, Nepafenac 0.3% and Diclofenac 0.1% in Patients After Cataract SurgeryRecruitingNot applicableNemocnice KolínNCT07178639Written as diclofenac 0.1% ophthalmic susp.
- Diclofenac for Prevention of Post-ERC PancreatitisNot yet recruitingPhase 2/3Karolinska InstitutetNCT03595150Written as Diclofenac
- Effect of Genetic Polymorphisms on Response to Preoperative NSAIDs in Endodontic Postoperative Pain ManagementRecruitingNot applicableAtaturk UniversityNCT06937853Written as diclofenac sodium
- The Antimicrobial Potential of Diclofenac Sodium as an Intracanal MedicamentRecruitingPhase 2/3British University In EgyptNCT06207253Written as Diclofenac Sodium
- Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone FractureRecruitingPhase 1ZetrOZ, Inc.NCT05883241Written as 2.5% Diclofenac Patches
- Sustained Acoustic Medicine for Osteoarthritis PainRecruitingPhase 1ZetrOZ, Inc.NCT05254574Written as 2.5% Diclofenac Patches
- Comparison of the Efficacy of Diclofenac Sodium and Subcutaneous 5% Dextrose Injection in Low Back Pain.Enrolling by invitationPhase 1/2Aksaray University Training and Research HospitalNCT06829030Written as 5% dextrose prolotherapy
- Evaluation of the Effect of Intra-ligamentary Injection of Diclofenac Potassium Versus Articaine on Anaesthetic Efficacy in Mandibular Molars With Symptomatic Irreversible Pulpitis.Not yet recruitingEarly Phase 1Cairo UniversityNCT06500871Written as Diclofenac Potassium
- Effects of Opioids and NSAIDs on Sympathetic Nervous System and Vascular FunctionRecruitingPhase 4University of ZurichNCT03781544Written as Diclofenac
- Intracutaneous Sterile Water and Diclofenac Sodium Injections in Renal ColicNot yet recruitingNot applicableSuez Canal UniversityNCT06342648Written as Diclofenac Sodium injection
- Efficacy of Preoperative Diclofenac Potassium- Acetaminophen Combination on Anesthetic Success in Patients With Symptomatic Irreversible Pulpitis: a Randomized Controlled TrialCompletedNot applicableCairo UniversityNCT04593160Written as Diclofenac potassium
- Diclofenac Dose Response StudyCompletedPhase 1University of Maryland, BaltimoreNCT06636227Written as Diclofenac 100mg
- Analgesic Equivalence of NSAIDs and Tramadol in Acute Postoperative Pain Following Minimally Invasive SurgeryCompletedNot applicableISSSTE Hospital Regional "Gral. Ignacio Zaragoza"NCT07500454Written as Diclofenac
- Efficacy of Nonsteroidal Anti-Inflammatory Drugs for the Prevention of Cystoid Macular Edema Following Cataract PhacoemulsificationCompletedPhase 4Pomeranian Medical University SzczecinNCT07696104Written as diclofenac 0.1% ophthalmic susp.
See all 210 studies that test Diclofenac →
Given in every arm · 22 — Diclofenac is usual care beside what is tested
- Cold Water Papillary Irrigation Plus Rectal NSAIDs vs Rectal NSAIDs Alone for Post-ERCP Pancreatitis (COLD)Not yet recruitingNot applicableUniversity Hospital Virgen de las NievesNCT07885852Written as Rectal NSAID (diclofenac 100 mg)
- Contribution of UGT2B17 to the Pharmacokinetics of DiclofenacRecruitingEarly Phase 1Washington State UniversityNCT06053411Written as Diclofenac
- Nebulized Salbutamol in Acute Renal ColicNot yet recruitingNot applicableOman Medical Speciality BoardNCT06276231Written as Diclofenac Injection
- Study of PHN131 in Patients After SurgeryCompletedPhase 2/3PhytoHealth CorporationNCT02193620Written as Diclofenac
- Efficacy of Different Drugs to Control Post Root Canal Treatment PainCompletedPhase 2University of KhartoumNCT02417337Written as Diclofenac
- Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and HipTerminatedPhase 2Regeneron PharmaceuticalsNCT03949673Written as Diclofenac
- COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICACompletedPhase 3Pakistan Institute of Medical SciencesNCT05626140Written as Diclofenac Sodium
- Evaluate the Ability of dOFM for BE Testing of Topically Applied Diclofenac Sodium Products in Healthy SubjectsCompletedNot applicableJoanneum Research Forschungsgesellschaft mbHNCT04592016Written as Pennsaid 2 % Topical Solution (Horizon Therapeutics, USA)
- Treatment of Renal Colic in the Emergency Departement (ED).CompletedPhase 2University of MonastirNCT03199924Written as Diclofenac
- Evaluation of the Roll of IV Fluids in the Treatment of Renal ColicWithdrawnPhase 4Sheba Medical CenterNCT03529097Written as Optalgin, Voltaren, Morphine
- Effectiveness of Chiropractic Application for Acute Low Back PainCompletedPhase 2Medipol UniversityNCT04110119Written as diclophenac sodium (75 mg, IM) and thiocolchicoside (4 mg, IM)
- Tamsulosin as Adjunctive Therapy After Extracorporeal Shock Wave Lithotripsy for Renal StonesCompletedPhase 4Hospital Regional de Alta Especialidad del BajioNCT04819828Written as Diclofenac
- Analgesic Efficacy And Safety of Tanezumab Added On To Diclofenac SR In Patients With Osteoarthritis Of The Knee Or HipTerminatedPhase 3PfizerNCT00864097Written as diclofenac
- Pregabalin Versus Hydrocortisone for Postdural Puncture Headache After Spinal for CesareanCompletedPhase 4Cairo UniversityNCT03910088Written as Diclofenac
- Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy VolunteersCompletedPhase 1Anne ChangNCT03072485Written as Diclofenac
- Dabigatran in an Interaction Probe Drug CocktailCompletedPhase 1Turku University HospitalNCT02361619Written as Diclofenac
- Pharmacokinetics Study Comparing Topical Diclofenac/Menthol Gels With Voltaren Gel and Oral Diclofenac SodiumCompletedPhase 1GlaxoSmithKlineNCT02201238Written as Diclofenac sodium
- Safety and Efficacy of Neuromultivit in Treatment of Vertebrogenic RadiculopathyCompletedPhase 3Bausch Health Americas, Inc.NCT02508805Written as Voltaren
- A Study Investigating Pain Following Single-port or Multi-port Video Assisted Thoracoscopic SurgeryWithdrawnNot applicableUniversity Hospitals Bristol and Weston NHS Foundation TrustNCT02556970Written as Diclofenac
- Effects of Systemic or Adjunct Tramadol Addition to Lidocaine Used for IVRA in Patients Undergoing Hand SurgeryCompletedPhase 3Bagcilar Training and Research HospitalNCT02658721Written as Diclofenac sodium
Showing 20 of 22.
As the comparator · 60 — what is tested is compared with Diclofenac
- Indomethacin vs Diclofenac for Preventing PEPRecruitingNot applicableAir Force Military Medical University, ChinaNCT07071441Written as Diclofenac 100mg
- Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone DiseaseRecruitingPhase 1/2University of Texas Southwestern Medical CenterNCT06158620Written as oral diclofenac
- Impact of Gel Aromatherapy on Pain for Patients With De Quervain DiseaseRecruitingPhase 4University Hospital, Strasbourg, FranceNCT06012097Written as Diclofenac gel
- Topical Treatment for TMJ ArthralgiaRecruitingPhase 3University of the PacificNCT05816226Written as Diclofenac 1% topical
- Effectiveness of Tricortin 1000 in Patients Affected by Chronic Low Back PainRecruitingPhase 4Fidia Farmaceutici s.p.a.NCT04585334Written as Itami
- COMPARİSON OF THE EFFECTS OF ULTRASOUND-GUİDED ERECTOR SPİNAE PLANE BLOCK AND INTRAMUSCULAR NONSTEROİDAL ANTİ-INFLAMMATORY DRUG ADMİNİSTRATİON ON INTRAOPERATİVE ANALGESİA AND PATİENT SATİSFACTİON DURİNG EXTRACORPOREAL SHOCK WAVE LİTHOTRİPSYCompletedNot applicableSanliurfa Mehmet Akif Inan Education and Research HospitalNCT07880535Written as Diclofenac Sodium (DCS)
- Integrated Traditional Chinese and Western Medicine for Patellar Dislocation Pain: A Concurrent Non-Randomized Controlled TrialCompletedNot applicablePeking University Third HospitalNCT07613346Written as Voltaren
- The Effect of Three Different Medications on Anesthetic Success and Postoperative PainCompletedNot applicableCairo UniversityNCT06298383Written as Diclofenac Potassium 50mg Tab
- Topical Capsaicin Versus Diclofenac for Chronic Temporomandibular Joint-Related PainCompletedNot applicableIstanbul UniversityNCT07598994Written as Diclofenac 1% Topical
- Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to OsteoarthritisCompletedPhase 2ZetrOZ, Inc.NCT06257537Written as 2.5% Diclofenac Patches
- An Efficacy and Safety Study of Tramadol/Acetaminophen Versus Diclofenac in the Treatment of Pain in Participants With Ankylosing Spondylitis Receiving Stable Treatment of Disease Modifying Anti-rheumatic Drugs (DMARDs)TerminatedPhase 4Johnson & Johnson Taiwan LtdNCT00766402Written as Diclofenac
- Counterpain PXM Versus Diclofenac Versus PiroxicamCompletedPhase 3Taisho Pharmaceutical IndonesiaNCT07475663Written as Diclofenac Sodium 10 mg (Brand Name Hotin® DCL)
- Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to OsteoarthritisCompletedPhase 2ZetrOZ, Inc.NCT05882812Written as 2.5% Diclofenac Patches
- Piroxicam Versus Diclofenac for Post Caesarean Section AnalgesiaCompletedNot applicableFederal Teaching Hospital AbakalikiNCT06943092Written as Diclofenac group
- A Study of Tirbanibulin Ointment and Diclofenac Sodium Gel for the Treatment of Adult Participants With Actinic Keratosis on the Face or ScalpActive, not recruitingPhase 4Almirall, S.A.NCT05387525Written as Diclofenac Sodium 3% Gel
- A Clinical Trial to Compare Safety and Effectiveness for Relieving Tenderness of 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel in the Treatment of Strains and Bruises of the Legs.CompletedPhase 2BayerNCT05026320Written as Diclofenac gel
- 5% KOH Solution vs. Placebo and Diclofenac Gel for the Treatment of Actinic KeratosisCompletedPhase 3Infectopharm Arzneimittel GmbHNCT04552327Written as Solaraze
- Study to Assess the Efficacy and Safety of Meloxicam vs. Diclofenac SR in Patients With Osteoarthritis of the KneeCompletedPhase 4Boehringer IngelheimNCT02183129Written as Diclofenac
- Comparative Evaluation of the Effectiveness of Diclofenac Sodium Versus Vitamin D on Myofascial PainCompletedPhase 4Yuzuncu Yıl UniversityNCT06111573Written as Diclofenac Sodium
- Clinical Study of Ningmitai Capsule on Promoting the Passage of Residual Fragments After Ureteroscopic LithotripsyCompletedPhase 4Xintian PharmaceuticalNCT06105827Written as Control group
Showing 20 of 60.
Codes
What other systems call Diclofenac · ClinicalTrials.gg INT007339
- MeSH (NLM) D004008DiclofenacConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 144O8QL0L1DICLOFENACConfirmed FDA, NLM, Wikidata
- RxNorm 3355Confirmed FDA, Wikidata
- Wikidata Q244408DiclofenacConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C28985DiclofenacOne source FDA
- DrugBank DB00586One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004008 | Diclofenac | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 144O8QL0L1 | DICLOFENAC | Confirmed FDA, NLM, Wikidata |
| RxNorm | 3355 | — | Confirmed FDA, Wikidata |
| Wikidata | Q244408 | Diclofenac | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C28985 | Diclofenac | One source FDA |
| DrugBank | DB00586 | — | One source Wikidata |
Also registered as diclofenac potassium (UNII L4D5UA6CB4 · RxNorm 81997) and diclofenac sodium (UNII QTG126297Q · RxNorm 203214).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.