Drug
Pregabalin clinical trials
Also written Lyrica, Lyrica 150mg and YHD1119.
How each study uses Pregabalin is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Pregabalin studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Approvals
The first approval found in each region, with its record
- United States
- 30 Dec 2004 · LYRICA · NDA 021446 (FDA, Drugs@FDA)
- European Union
- 5 Jul 2004 · Lyrica · EMEA/H/C/000546 (EMA)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
388 studies that test it; most in 2011 (28)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 1998 | 2 |
| 1999 | 2 |
| 2001 | 4 |
| 2002 | 4 |
| 2004 | 7 |
| 2005 | 18 |
| 2006 | 27 |
| 2007 | 25 |
| 2008 | 27 |
| 2009 | 22 |
| 2010 | 21 |
| 2011 | 28 |
| 2012 | 18 |
| 2013 | 11 |
| 2014 | 15 |
| 2015 | 17 |
| 2016 | 12 |
| 2017 | 11 |
| 2018 | 17 |
| 2019 | 14 |
| 2020 | 12 |
| 2021 | 16 |
| 2022 | 15 |
| 2023 | 11 |
| 2024 | 9 |
| 2025 | 9 |
| 2026 | 13 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 139 · Other 251
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (86) · Pfizer (18) · Beijing Tiantan Hospital (12) · Cairo University (6) · Yuhan Corporation (6) · Tel-Aviv Sourasky Medical Center (5) · Rambam Health Care Campus (4) · Mansoura University (4)
Often tested with
Tested in the same studies.
Duloxetine (19) · Acetaminophen (10) · Gabapentin (9) · Celecoxib (8) · Dexmedetomidine (5) · Tramadol (4) · Oxycodone (4) · Melatonin (4)
Related medicines
As reviewed, each with the page that says it.
- One of Analgesics source
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Tested against it · 2 phase 3 studies under way
Pregabalin is the comparator. A study of two new drugs counts under both.
- 1Suzetrigine · Vertex Pharmaceuticals Incorporated · next primary completion May 2027
Reaching primary completion within a year · 13, 1 in phase 3
Studies that test Pregabalin, phase 3 first.
- Jun 2027Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic NeuralgiaPhase 3 · Brainfarma Industria Química e Farmacêutica S/A
- Dec 2026Effect of Preoperative Oral Pregabalin Versus Intraoperative Fentanyl on Postoperative AnalgesiaEarly Phase 1 · Ain Shams University
- Dec 2026Effect of Pregabalin on Optic Nerve Sheath Diameter in Craniotomy Patients.Not applicable · Benha University
- Jan 2027Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain SyndromeNot applicable · Cairo University
- Apr 2027Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)Phase 2 · Jules Bordet Institute
- Jun 2027Pregabalin for Chronic Pelvic Pain in WomenNot applicable · Beijing Tiantan Hospital
- Jun 2027Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine SurgeryNot applicable · Tanta University
- Jun 2027The Efficacy and Safety of Pregabalin Combined With Venlafaxine in Patients With FibromyalgiaNot applicable · Beijing Tiantan Hospital
- Jun 2027The Efficacy and Safety of Pregabalin Combined With Dexmedetomidine in Patients With FibromyalgiaNot applicable · Beijing Tiantan Hospital
- Jun 2027The Efficacy and Safety of Pregabalin Combined With Toludesvenlafaxine in Patients With FibromyalgiaNot applicable · Beijing Tiantan Hospital
Studies
Open first, then newest update. How each study uses Pregabalin is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 390
- Human Experimental Models of Pain (HEMP)Not yet recruitingNot applicableNational Center for Complementary and Integrative Health (NCCIH)NCT07549490Written as Pregabalin
- Pregabalin for Chronic Pelvic Pain in WomenNot yet recruitingNot applicableBeijing Tiantan HospitalNCT07818577Written as Pregabalin
- Comparison of Two Postoperative Care Strategies After Breast SurgeryRecruitingNot applicableMoumtzidou Maria AikateriniNCT07880223Written as Pregabalin
- A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patients With Refractory or Unexplained Chronic CoughNot yet recruitingPhase 4McMaster UniversityNCT07288528Written as Pregabalin
- Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)RecruitingPhase 2Jules Bordet InstituteNCT06150898Written as Pregabalin 75mg
- SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy.RecruitingPhase 2University of RochesterNCT06614322Written as Pregabalin
- The Efficacy and Safety of Pregabalin Combined With Venlafaxine in Patients With FibromyalgiaRecruitingNot applicableBeijing Tiantan HospitalNCT07186751Written as Pregabalin
- Efficacy and Safety of Pregabalin Combined With Educational and Behavioral Intervention for Bladder Pain Syndrome/Interstitial CystitisNot yet recruitingPhase 1Beijing Tiantan HospitalNCT07752134Written as Pregabalin
- Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic NeuralgiaRecruitingPhase 3Brainfarma Industria Química e Farmacêutica S/ANCT07712913Written as Experimental: Pregabalin XR
- Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in U.S. Healthy ParticipantsNot yet recruitingPhase 1Neurodawn Pharmaceutical Co., Ltd.NCT07618715Written as Pregabalin capsule
- Effectiveness of Opioid vs Pregabalin Plus Naproxen Sodium in Pain Management of Oral Cancer PatientsEnrolling by invitationNot applicableMayo Hospital LahoreNCT07606638Written as Pregabalin + Naproxen Sodium
- Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain SyndromeRecruitingNot applicableCairo UniversityNCT07421427Written as Pregabalin
- Efficacy and Safety of Pregabalin/Tizanidine vs. Pregabalin in Patients With FibromyalgiaNot yet recruitingNot applicableBeijing Tiantan HospitalNCT07382921Written as Pregabalin
- Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine SurgeryRecruitingNot applicableTanta UniversityNCT07344467Written as Pregabalin capsule
- Efficacy of Pregabalin for Diabetic Pruritus - A Randomized Controlled Study.RecruitingPhase 4Post Graduate Institute of Medical Education and Research, ChandigarhNCT06790537Written as Pregabalin 75 mg
- The Efficacy and Safety of Pregabalin Combined With Dexmedetomidine in Patients With FibromyalgiaRecruitingNot applicableBeijing Tiantan HospitalNCT07230197Written as Pregabalin
- The Efficacy and Safety of Pregabalin Combined With Toludesvenlafaxine in Patients With FibromyalgiaRecruitingNot applicableBeijing Tiantan HospitalNCT07208357Written as Pregabalin
- The Efficacy and Safety of Pregabalin Combined With Desvenlafaxine in Patients With FibromyalgiaRecruitingNot applicableBeijing Tiantan HospitalNCT07171320Written as Pregabalin
- Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass GraftingRecruitingPhase 4Tanta UniversityNCT05640453Written as Pregabalin
- Prophylactic Pregabalin Treatment Following Spinal Cord InjuryRecruitingNot applicableLoewenstein HospitalNCT06066918Written as Pregabalin 75mg
See all 390 studies that test Pregabalin →
Given beside what is tested · 10 — Pregabalin is usual care or a partner of the new treatment
- Efficacy of Electroacupuncture for Acute Herpes Zoster-Associated Pain and Biomarker EvaluationRecruitingNot applicableDexiong HanNCT07515885Written as Valacyclovir, pregabalin and mecobalamin
- Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth SyndromeRecruitingPhase 3Federico II UniversityNCT06025474Written as Pregabalin 75mg
- Opioid-Free Pain Protocol After Shoulder ArthroplastyActive, not recruitingPhase 4Henry Ford Health SystemNCT05488847Written as Pregabalin
- Pre vs Post Block in Total Knee Arthroplasty (TKA)CompletedPhase 4University of MiamiNCT05974501Written as Lyrica
- A Study To Compare Pregabalin/PF-00489791 Combination Versus Pregabalin Alone In Post-Herpetic NeuralgiaCompletedPhase 2PfizerNCT00599638Written as pregabalin
- Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting AbilityCompletedPhase 2AstraZenecaNCT01928381Written as AZD5213 + pregabalin
- Effects of Duloxetine on Pain Relief After Total Knee Arthroplasty in Central Sensitization PatientStatus unknownNot applicableThe Catholic University of KoreaNCT02600247Written as celecoxib, Pregabalin, acetaminophen/tramadol, oxycodone
- Magnesium Oral Supplementation to Reduce Pain Inpatients With Severe Peripheral Arterial Occlusive DiseaseStatus unknownNot applicableAzienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaNCT02455726Written as Pregabalin
- Functional Neuroimaging in Fibromyalgia Patients Receiving tDCSStatus unknownPhase 2Hospital de Clinicas de Porto AlegreNCT01904097Written as Pregabalin
- Efficacy and Safety of KW21052 Compared to Lyrica in the Diabetic Patients With Neuropathic PainStatus unknownPhase 3KunWha Pharmaceutical Co., Ltd.NCT01863810Written as Lyrica
As the comparator · 65 — what is tested is compared with Pregabalin
- Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral NeuropathyRecruitingPhase 3Vertex Pharmaceuticals IncorporatedNCT06628908Written as Pregabalin
- A Clinical Trial to Evaluate the Efficacy and Safety of HL-1186 Tablet in the Treatment of Postherpetic NeuralgiaRecruitingPhase 2Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.NCT07758920Written as Pregabalin capsule
- Comparing Efficiency of Mirogabalin and Pregabalin in Primary TKARecruitingNot applicableThammasat University HospitalNCT06328062Written as Pregabalin
- The Efficacy and Safety of Pregabalin and Mirogabalin in Patients With FibromyalgiaRecruitingNot applicableBeijing Tiantan HospitalNCT07157852Written as Pregabalin
- Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral NeuropathyRecruitingPhase 2Vertex Pharmaceuticals IncorporatedNCT06619860Written as Pregabalin
- Y-4 to Treat the Postherpetic NeuralgiaRecruitingPhase 2Neurodawn Pharmaceutical Co., Ltd.NCT07275762Written as Pregabalin
- A Study of HRS-2129 in Patients With Diabetic Peripheral Neuropathic PainRecruitingPhase 1Shandong Suncadia Medicine Co., Ltd.NCT07377721Written as Pregabalin Capsules
- Efficacy and Safety of Mirogabalin in Diabetic Peripheral Neuropathic PainRecruitingPhase 4Bangladesh Medical UniversityNCT07451431Written as Pregabalin
- The Efficacy and Safety of Pregabalin and Crisugabalin in Patients With FibromyalgiaRecruitingNot applicableBeijing Tiantan HospitalNCT07196657Written as Pregabalin
- Crisugabalin for Radiotherapy-Related Neuropathic PainRecruitingPhase 2Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT06766916Written as Pregabalin
- Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic NeuralgiaRecruitingNot applicableCMH Kharian Medical CollegeNCT06969417Written as Pregabalin
- Efficacy and Safety of Praga Formulation in the Treatment of Neuropathic PainRecruitingPhase 3EMSNCT04666714Written as Pregabalin 75mg
- Evaluate the Efficacy and Safety of JMKX000623 in Participants With Diabetic Peripheral Neuropathic PainRecruitingPhase 2JemincareNCT06221241Written as Pregabalin
- Focal Microvibration and Chronic Lumbosacral Radicular PainNot yet recruitingNot applicableFederico II UniversityNCT06301061Written as Gabapentin; Pregabalin; Duloxetine; Amitriptyline
- Study on the Efficacy and Safety of Tongluo Kaibi Tablets in the Treatment of Fibromyalgia SyndromeCompletedPhase 4Guang'anmen Hospital of China Academy of Chinese Medical SciencesNCT07708948Written as Pregabalin capsule
- Tapentadol vs Pregabalin for Postoperative Pain in Lower Limb SurgeryCompletedNot applicableISSSTE Hospital Regional "Gral. Ignacio Zaragoza"NCT07587645Written as Pregabalin
- Evaluation in the Treatment of Neuropathic Pain Post Breast SurgeryCompletedPhase 3Institut Cancerologie de l'OuestNCT03794388Written as Pregabalin
- Efficacy and Safety of the N0750 Compared to Monotherapies in the Treatment of Painful Diabetic Peripheral NeuropathyWithdrawnPhase 3Eurofarma Laboratorios S.A.NCT06715462Written as Lyrica®
- Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN)CompletedPhase 2Vertex Pharmaceuticals IncorporatedNCT05660538Written as Pregabalin
- Comparison of Ba-Duan-Jin and Pregabalin in Patients with FibromyalgiaCompletedNot applicableGuang'anmen Hospital of China Academy of Chinese Medical SciencesNCT03797560Written as Pregabalin capsule
Showing 20 of 65.
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting1
- Comparison of Two Postoperative Care Strategies After Breast SurgeryOct 20, 2026NCT07880223
Newly registered1
- Comparison of Two Postoperative Care Strategies After Breast SurgeryOct 19, 2026NCT07880223
Codes
What other systems call Pregabalin · ClinicalTrials.gg INT006615
- MeSH (NLM) D000069583PregabalinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 55JG375S6MPREGABALINConfirmed FDA, NLM, Wikidata
- RxNorm 187832Confirmed FDA, Wikidata
- Wikidata Q412174pregabalinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C64625PregabalinOne source FDA
- DrugBank DB00230One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069583 | Pregabalin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 55JG375S6M | PREGABALIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 187832 | — | Confirmed FDA, Wikidata |
| Wikidata | Q412174 | pregabalin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C64625 | Pregabalin | One source FDA |
| DrugBank | DB00230 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.