Neuralgia, Postherpetic clinical trials
The registry lists 196 studies for Neuralgia, Postherpetic across more than 10 countries. 28 are recruiting or about to start. 144 of them are mainly about Neuralgia, Postherpetic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03.
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Who runs them
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (8) · Pfizer (7) · NeurogesX (5) · Merck Sharp & Dohme LLC (5) · Seoul National University (5) · Beijing Tiantan Hospital (4) · University of California, San Francisco (4) · UCB Pharma (4)
What is being tested here
Drugs under test in Neuralgia, Postherpetic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Pregabalin | 3 | 5 | 15 |
| Lacosamide | 1 | 0 | 3 |
| Esketamine | 1 | 0 | 2 |
| Riluzole | 1 | 0 | 1 |
| HL-1186 | 1 | 0 | 1 |
| Platelet rich plasma | 1 | 0 | 1 |
| Capsaicin | 0 | 2 | 7 |
| Lidocaine | 0 | 2 | 5 |
| Gabapentin | 0 | 3 | 5 |
| Botulinum toxin type A | 0 | 0 | 4 |
Drug classes tested here Local anesthetics 6 · Opioids 6 · NSAIDs 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6, phase 3 first
- Jun 2027Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia · Phase 3 · Brainfarma Industria Química e Farmacêutica S/A
- Dec 2026Electroacupuncture for PHN: Efficacy and Biomarker Evaluation in a Multicenter, Randomized, Sham-Controlled Trial Protocol · Dexiong Han
- Dec 2026Transcranial Magnetic Stimulation for Chronic Neuropathic Pain · University of California, San Francisco
- Dec 2026Early Screening Markers of Herpes Zoster Neuralgia · Tongji Hospital
- Jun 2027A Clinical Trial to Evaluate the Efficacy and Safety of HL-1186 Tablet in the Treatment of Postherpetic Neuralgia · Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.
- Sep 2027The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster · Beijing Tiantan Hospital
Who these studies take
Of the 18 Neuralgia, Postherpetic studies recruiting now, 8 (44%) set no upper age limit and 5 (28%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 13 (72%) | 13 (72%) |
| 30 | 16 (89%) | 16 (89%) |
| 40 | 17 (94%) | 17 (94%) |
| 50 | 18 (100%) | 18 (100%) |
| 65 | 17 (94%) | 17 (94%) |
| 75 | 16 (89%) | 16 (89%) |
| 85 | 10 (56%) | 10 (56%) |
Across all 196 studies, recruiting or not: 12% stop at 75 or younger and 4% at 65; 2% take children; 0% are for women only and 2% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Neuralgia, Postherpetic studies take
Of 12 phase 2 interventional studies under Neuralgia, Postherpetic, half reached primary completion within 12 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 12 mo9–17 · 12 studies | — | — |
| Interventional, no phase | 16 mo10–35 · 32 studies | — | 16 mo10–35 · 30 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Results posted1
- Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic NeuralgiaOct 29, 2026NCT07123987
Studies
Recruiting first, then most recently updated. Showing 50 of 196. Browse all 196 → or search them.
- Simultaneous Engagement of Networks for Alleviating Pain (SENAP)Not yet recruitingNCT07057206Phase 11 country
- The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes ZosterRecruitingNCT07361796Not applicable1 country
- A Clinical Trial to Evaluate the Efficacy and Safety of HL-1186 Tablet in the Treatment of Postherpetic NeuralgiaRecruitingNCT07758920Phase 21 country
- Closed-Loop Deep Brain Stimulation for Refractory Chronic PainRecruitingNCT04144972Not applicable1 country
- Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic NeuralgiaRecruitingNCT07712913Phase 31 country
- Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in U.S. Healthy ParticipantsNot yet recruitingNCT07618715Phase 11 country
- Y-4 to Treat the Postherpetic NeuralgiaRecruitingNCT07275762Phase 21 country
- Intradermal Exosomes, Platelet-Rich Plasma, and Steroids for Post-Herpetic NeuralgiaRecruitingNCT07565844Not applicable1 country
- Erector Spinae Plane Block Versus Transcutaneous Radiofrequency in Postherpetic NeuralgiaRecruitingNCT074006401 country
- Efficacy of Transcutaneous Pulsed Radiofrequency in Postherpetic NeuralgiaRecruitingNCT073902791 country
- Brain Stimulation for Postherpetic Neuralgia: A Randomized Sham-Controlled TrialNot yet recruitingNCT07352553Not applicable1 country
- Comparison Between the Efficacy of Ultrasound-guided Erector Spinae Plane Block and Conventional Treatment for Pain Management in Patients With Post-herpetic NeuralgiaRecruitingNCT07256145Not applicable1 country
- Pulsed Radiofrequency in Post Herptic NeuralgiaNot yet recruitingNCT07208032Not applicable1 country
- Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMARecruitingNCT057541901 country
- Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Peripheral Neuropathic Pain.RecruitingNCT06290661Not applicable1 country
- Electroacupuncture for PHN: Efficacy and Biomarker Evaluation in a Multicenter, Randomized, Sham-Controlled Trial ProtocolNot yet recruitingNCT06990854Not applicable1 country
- Early Screening Markers of Herpes Zoster NeuralgiaNot yet recruitingNCT07038707
- The Effectiveness of Ultra-Sound Guided Erector Spinae Block With Betamethasone for Management of Truncal Chronic Post Herpetic Neuralgia.RecruitingNCT07000409Not applicable1 country
- Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic NeuralgiaRecruitingNCT06969417Not applicable1 country
- High-Voltage Long-Duration Pulsed Radiofrequency Combined With Liposomal Bupivacaine Subcutaneous Block for Herpes Zoster-Associated NeuralgiaRecruitingNCT06959147Phase 41 country
- Esketamine Combined Pregabalin and Duloxetine for Postherpetic NeuralgiaRecruitingNCT06896994Not applicable1 country
- Esketamine Combined With PRF of DRG for Postherpetic NeuralgiaNot yet recruitingNCT06914193Not applicable1 country
- The Treatment of Postherpetic Neuralgia in the Head and Face With Superficial Needling Combined With ElectroacupunctureRecruitingNCT06420778Not applicable1 country
- Effectiveness of Warm Acupuncture in Patients with Postherpetic NeuralgiaNot yet recruitingNCT06893172Not applicable
- A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.RecruitingNCT06218784Phase 11 country
- The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Sympathetic Ganglion BlockNot yet recruitingNCT06130514Not applicable
- Predictive Models for the Treatment of Recurrent Herpes Zoster Neuralgia Following Spinal Cord Electrical Stimulation.Enrolling by invitationNCT064102221 country
- Incidence of Intravascular (IV) Injection During Trigeminal Nerve BlocksRecruitingNCT044673981 country
- Postherpetic Neuralgia After Herpes Zoster and Incident Dementia RiskCompletedNCT073992881 country
- Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic NeuralgiaCompletedNCT07123987Not applicable1 country
- Transcranial Magnetic Stimulation for Chronic Neuropathic PainActive, not recruitingNCT05593237Not applicable1 country
- Obesity and Obesity-Related Factors and Risk of Herpes Zoster (Shingles) and Postherpetic NeuralgiaActive, not recruitingNCT06638177
- Efficacy and Safety of High-Concentration 35 kDa Hyaluronan Gel for Herpes Zoster-Associated PainCompletedNCT07569978Not applicable1 country
- The Analgesic Effect of Electroacupuncture on Postherpetic NeuralgiaCompletedNCT04560361Not applicable1 country
- Subcutaneous Lidocaine Injection in Acute Herpes Zoster Neuralgia and Post-herpetic NeuralgiaCompletedNCT06882525Not applicable1 country
- Clinical and Economic Impact of Herpes Zoster in Cancer PatientsCompletedNCT062074871 country
- A Study of ONO-1110 in Patients With Postherpetic NeuralgiaCompletedNCT06708416Phase 21 country
- A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve InjuryCompletedNCT06091020Phase 26 countries
- Dorsal Root Ganglion Stimulation in Postherpetic NeuropathyCompletedNCT062259601 country
- Efficacy and Safety of LX9211 in Participants With Postherpetic NeuralgiaCompletedNCT04662281Phase 23 countries
- Predictors of Success After Intercostal Nerve Radiofrequency Treatment for Intercostal NeuralgiaCompletedNCT073671521 country
- Ultrasound-Guided Thoracic Paravertebral Block With Steroid and Local Anesthetic for Acute Herpes Zoster: Effects on Pain Control and Prevention of Postherpetic NeuralgiaCompletedNCT07349680Phase 31 country
- Effectiveness of Ultrasonography-Guided Serratus Posterior Superior Intercostal Plane Block in Thoracic Postherpetic Neuralgia: A Retrospective Cohort StudyCompletedNCT070678921 country
- Establishment of a Prediction Model for Postherpetic NeuralgiaCompletedNCT072717841 country
- Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic NeuralgiaCompletedNCT01106716Phase 21 country
- Stellate Ganglion Block in Herpes ZosterCompletedNCT04188327Not applicable1 country
- Rhomboid Intercostal and Subserratus Plane Block Versus Paravertebral Block for Thoracic Herpes ZosterCompletedNCT06751680Not applicable1 country
- The Success of Lumbar Sympathetic Ganglion Block Using Lower Extremity Perfusion IndexCompletedNCT06241820Not applicable1 country
- A SAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy VolunteersCompletedNCT05496205Phase 11 country
- A Multi-Centre, Randomized, Double-Blind, Placebo Controlled Pilot Trial to Assess the Efficacy, Safety, and Tolerability of SPM 927 in Subjects With Postherpetic Neuralgia (PHN).CompletedNCT00861068Phase 2