Drug
Drospirenone clinical trials
- studies test it
- 37
- open now
- 5
- in phase 3
- 9
- first study started
- 2005
Keep track of what changes. Save the drospirenone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Studies by the year they started
37 studies that test it; most in 2007 (4)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2006 | 1 |
| 2007 | 4 |
| 2008 | 4 |
| 2009 | 2 |
| 2010 | 1 |
| 2012 | 1 |
| 2013 | 1 |
| 2014 | 1 |
| 2015 | 2 |
| 2016 | 4 |
| 2017 | 2 |
| 2018 | 1 |
| 2021 | 1 |
| 2022 | 2 |
| 2023 | 3 |
| 2024 | 4 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 11
- Phase 2
- 6
- Phase 3
- 9
- Phase 4
- 10
- No phase
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 23 · Other 14
Estetra (6) · Bayer (6) · Massachusetts General Hospital (3) · Insud Pharma (2) · Janssen Research & Development, LLC (2) · Chulalongkorn University (2) · Janssen Pharmaceutica N.V., Belgium (1) · NewAmsterdam Pharma (1)
Often tested with
Tested in the same studies.
Ethinyl Estradiol (16) · Estetrol (8) · Estradiol (8) · Midazolam (4) · Dienogest (2) · Milvexian (1) · TA-8995 (1) · Retatrutide (1)
Studies
Open first, then newest update. How each study uses drospirenone is read from its arms, and is right about nine times in ten.
Testing it · 37
- A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced MalignanciesRecruitingPhase 1Novartis PharmaceuticalsNCT07340190Written as drospirenone
- Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery StudyRecruitingPhase 1/2Chulalongkorn UniversityNCT06345560Written as Drospirenone
- Drospirenone Only Pills and Cervical Mucus Changes: A Pre- and Post-Bariatric Surgery StudyRecruitingNot applicableChulalongkorn UniversityNCT06345586Written as Drospirenone
- A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in PreeclampsiaNot yet recruitingPhase 4Oregon Health and Science UniversityNCT07293728Written as Drospirenone
- Estetrol/Drospirenone to Reduce the Average Size of EndometriomasRecruitingPhase 4Andrew ZakhariNCT05837624Written as Estetrol/Drospirenone
- LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult WomenActive, not recruitingPhase 4Insud PharmaNCT05303636Written as drospirenone 4 mg oral tablet or drospirenone 3.5 mg chewable tablet
- Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in FemalesCompletedPhase 3Insud PharmaNCT05461573Written as Drospirenone
- A Study of Milvexian in Healthy Adult FemalesCompletedPhase 1Janssen Pharmaceutica N.V., BelgiumNCT05706753Written as Drospirenone
- Evaluate the Pharmacokinetics of a Combined Oral Contraceptive (COC) With and Without ObicetrapibCompletedPhase 1NewAmsterdam PharmaNCT06250205Written as Obicetrapib + Drospirenone / Ethinyl Estradiol (COC)
- A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or ObeseCompletedPhase 1Eli Lilly and CompanyNCT06039826Written as Drospirenone
- The Use of Drospirenone/Estetrol, Nomegestrol Acetate/Estradiol and Ethinylestradiol/Dienogest in Random Start Rapid Endometrial PreparationCompletedPhase 4University of PalermoNCT06324851Written as Drospirenone / Estetrol
- E4/DRSP Ovarian Function Inhibition StudyCompletedPhase 2EstetraNCT03091595Written as 15 mg E4/3 mg DRSP
- Study in Women on the Effect of JNJ-64530440 on Oral Contraceptive and Midazolam, and the Effect of a High-fat Meal on JNJ-64530440WithdrawnPhase 1Janssen Research & Development, LLCNCT03890341Written as Drospirenone/Ethinylestradiol
- Effect of Two Different Dosages of Ethinyl-estradiol in Association With Drospirenone in Women With Polycystic Ovary Syndrome.CompletedNot applicableCatholic University of the Sacred HeartNCT01519401Written as 3 mg drospirenone and 20 µg ethinyl-estradiol
- E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - United States/Canada StudyCompletedPhase 3EstetraNCT02817841Written as 15 mg E4/3 mg DRSP
- E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - EU/Russia StudyCompletedPhase 3EstetraNCT02817828Written as 15 mg E4/3 mg DRSP
- Safety, Efficacy, Tolerability and Pharmacokinetics of LF111 (Drospirenone 4.0 mg) During 13 CyclesCompletedPhase 3Laboratories Leon Farma, S.A.NCT02269241Written as LF111 (drospirenone)
- Study to Evaluate Cycle Control With Norgestimate/Ethinyl Estradiol and Drospirenone/Ethinyl Estradiol in Healthy Sexually Active FemalesCompletedPhase 4Ortho-McNeil Janssen Scientific Affairs, LLCNCT00745901Written as Norgestimate/ethinyl estradiol; Drospirenone/ethinyl estradiol
- Estetrol (E4)/Drospirenone (DRSP) Drug-drug Interaction (DDI) StudyCompletedPhase 1EstetraNCT03512860Written as E4/DRSP
- "E4/DRSP Endocrine Function, Metabolic Control and Hemostasis Study"CompletedPhase 1/2EstetraNCT02957630Written as 15 mg E4/3 mg DRSP
See all 37 studies that test drospirenone →
Given in every arm · 4 — drospirenone is usual care beside what is tested
- A Drug-Drug Interaction Study Between HS-10374 Tablets and Drospirenone and Ethinyl Estradiol Tablets(Yasmin®)CompletedPhase 1Hansoh BioMedical R&D CompanyNCT07181343Written as Drospirenone and Ethinyl Estradiol tablets
- Efficacy and Safety of Dingkundan Combined With Combination Oral Contraceptives in the Treatment of PCOSCompletedNot applicableGuangdong Women and Children HospitalNCT05872425Written as Drospirenone and Ethinylestradiol Tablets (Ⅱ)
- Drug-drug Interaction Between Rifampicin and Progestins/Ethinylestradiol and MidazolamCompletedPhase 1BayerNCT03353857Written as Drospirenone, Ethinylestradiol/ Yasmin
- Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral ContraceptivesTerminatedPhase 2National Institute of Mental Health (NIMH)NCT00089414Written as Ethinyl Estradiol/Drospirenone
As the comparator · 4 — what is tested is compared with drospirenone
- A Study to Evaluate the Effectiveness of NuvaRing® to Prevent Pregnancies in Chinese Women (P06450)CompletedPhase 3Organon and CoNCT01277211Written as DRSP 3 mg + EE 30 µg
- LCS16 vs. COC User Satisfaction and Tolerability StudyCompletedPhase 3BayerNCT03074045Written as Ethinyl estradiol and drospirenone (Yarina, BAY86-5131)
- E4/DRSP Single and Multiple Dose PK and Early QT StudyCompletedPhase 1EstetraNCT02874248Written as 15 mg E4/3 mg DRSP
- Efficacy and Safety Study for an Oral Contraceptive Containing FolateCompletedPhase 3BayerNCT00468481Written as Drospirenone/Ethinylestradiol (Yaz)
Codes
What other systems call drospirenone · ClinicalTrials.gg INT003045
- MeSH (NLM) C035144drospirenoneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) N295J34A25DROSPIRENONEConfirmed FDA, NLM, Wikidata
- RxNorm 11636Confirmed FDA, Wikidata
- Wikidata Q419646drospirenoneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47502DrospirenoneOne source FDA
- DrugBank DB01395One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C035144 | drospirenone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | N295J34A25 | DROSPIRENONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 11636 | — | Confirmed FDA, Wikidata |
| Wikidata | Q419646 | drospirenone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47502 | Drospirenone | One source FDA |
| DrugBank | DB01395 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.