Central Serous Chorioretinopathy clinical trials
The registry lists 84 studies for Central Serous Chorioretinopathy across more than 10 countries. 14 are recruiting or about to start. 71 of them are mainly about Central Serous Chorioretinopathy (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Eye Institute (NEI) (5) · Manhattan Eye, Ear & Throat Hospital (3) · Peking University People's Hospital (3) · Samsung Medical Center (2) · Radboud University Medical Center (2) · Tel-Aviv Sourasky Medical Center (2) · Beijing Hospital (2) · Benha University (2)
What is being tested here
Drugs under test in Central Serous Chorioretinopathy studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Faricimab | 1 | 0 | 1 |
| Melatonin | 1 | 1 | 1 |
| Eplerenone | 0 | 1 | 4 |
| Finasteride | 0 | 0 | 3 |
| Aflibercept | 0 | 0 | 3 |
| Bevacizumab | 0 | 1 | 3 |
| Sildenafil | 0 | 0 | 1 |
| Interferon gamma-1b | 0 | 0 | 1 |
| Mifepristone | 0 | 0 | 1 |
| Verteporfin | 0 | 0 | 1 |
Drug classes tested here Angiogenesis inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Jan 2027Biomarkers and Choroidal Neovascularization · Institut National de la Santé Et de la Recherche Médicale, France
- May 2027Central Serous Chorioretinopathy and Micropulse Laser Treatment · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Jun 2027Prospective Geometric Analysis of Ultra-Widefield OCTA Characteristics in Central Serous Chorioretinopathy Patients · Sun Yat-sen University
- Jul 2027the Study of the Association Between the Gut Microbiota and Central Serous Chorioretinopathy · Second Affiliated Hospital, School of Medicine, Zhejiang University
Who these studies take
Of the 7 Central Serous Chorioretinopathy studies recruiting now, 2 (29%) set no upper age limit and 3 (43%) stop at 75 or younger. 2 (29%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (29%) | 2 (29%) |
| 18 | 7 (100%) | 7 (100%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 4 (57%) | 4 (57%) |
| 85 | 4 (57%) | 4 (57%) |
Across all 84 studies, recruiting or not: 45% stop at 75 or younger and 32% at 65; 11% take children; 0% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 84. Browse all 84 → or search them.
- A Case-Control Study Revealing Intraocular Microenvironment Characteristics in Patients With Ocular Diseases Based on Multi-Omics AnalysisNot yet recruitingNCT07897513
- Mindfulness for Central Serous ChorioretinopathyNot yet recruitingNCT07767058Not applicable1 country
- Biomarkers and Choroidal NeovascularizationRecruitingNCT044397081 country
- Faricimab for Chronic Central Serous Chorioretinopathy: A Randomized Sham-Controlled TrialNot yet recruitingNCT07681167Phase 2
- the Study of the Association Between the Gut Microbiota and Central Serous ChorioretinopathyRecruitingNCT06527326Not applicable1 country
- Prospective Geometric Analysis of Ultra-Widefield OCTA Characteristics in Central Serous Chorioretinopathy PatientsNot yet recruitingNCT073471191 country
- Wide Field OCTA in Ocular DiseasesNot yet recruitingNCT07298174
- Central Serous Chorioretinopathy and Micropulse Laser TreatmentRecruitingNCT063464051 country
- Evaluating Efficacy and Safety of Oral Melatonin in Acute Central Serous ChorioretinopathyNot yet recruitingNCT06809751Phase 2/3
- Subthreshold Nanosecond Laser for Non-resolving Central Serous ChorioretinopathyRecruitingNCT05570591Not applicable1 country
- Combination of Micropulse Laser With or Without Photodynamic Therapy for Chronic Central Serous ChorioretinopathyNot yet recruitingNCT06468540
- Steroid Eye Drops in Chronic Central Serous ChorioretinopathyRecruitingNCT05633576Phase 31 country
- Choroidal Blood Flow in Acute and Chronic Central Serous ChorioretinopathyRecruitingNCT055899741 country
- OCT in Rare Chorioretinal DiseasesRecruitingNCT021413081 country
- Treatment of Recurrent and Multifocal Central Serous ChorioretinopathyCompletedNCT07889518Not applicable1 country
- Sildenafil for Treatment of Choroidal IschemiaCompletedNCT04356716Phase 21 country
- Comfortable and Stabilizing Chin & Forehead Rest Attachment for Slit Lamp ConfigurationsTerminatedNCT05686421Not applicable1 country
- Intravitreal Bevacizumab for the Treatment of Central Serous ChorioretinopathyWithdrawnNCT00418431Phase 2/31 country
- Topical Interferon Gamma-1b for Central Serous ChorioretinopathyCompletedNCT01468337Phase 1/21 country
- Extension Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous ChorioretinopathyCompletedNCT01227993Phase 1/21 country
- Central Serous Chorioretinopathy Registry and Pachychoroid Observation and Natural History StudyActive, not recruitingNCT052781691 country
- Navigated Microsecond Laser for Chronic Central Serous Chorioretinopathy: MICROPULSEWithdrawnNCT05679180Not applicable
- Eplerenone, Aflibercept and Topical Nepafenac Serous Foveal Deta Chment in Central Serous ChorioretinopathyCompletedNCT058470491 country
- Selective Retinal Pigment Epithelium Laser Therapy for Macular Disease of the RetinaTerminatedNCT02088151Not applicable1 country
- Two Patterns of Micropulse Laser in the Treatment of Chronic Central Serous ChorioretinopathyStatus unknownNCT05687422Not applicable
- Subthreshold Micropulse Laser Treatment of Acute Central Serous ChorioretinopathyCompletedNCT05447117Not applicable1 country
- Different Doses of vPDT in the Treatment of cCSCStatus unknownNCT05390619Not applicable1 country
- Results of Suprachoroidal Steroids Injections in Two Chorioretinal DiseasesStatus unknownNCT05337332Phase 2/31 country
- 577nm Micropulse Laser vs Half-dose Photodynamic Therapy on Acute Central Serous ChorioretinopathyCompletedNCT02587767Not applicable1 country
- Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus PhotographCompletedNCT047231601 country
- Eplerenone Versus PDT: Comparative Study by OCTACompletedNCT05104138
- Crocin Supplementation in CSCRStatus unknownNCT04936490Phase 11 country
- PRedictive Factors and Changes From Treatment in iPCV Versus CSR Versus nAMD With afLiberceptStatus unknownNCT02681783Phase 41 country
- Pilot Study on Deep Learning in the EyeStatus unknownNCT04665102
- Panmacular Versus Minimal Micropulse Laser Therapy in Central Serous ChorioretinopathyStatus unknownNCT04410861Not applicable1 country
- Treatment of Chronic Central Serous Chorioretinopathy Via Electromagnetic Stimulation and Platelet- Rich PlasmaCompletedNCT04224831Not applicable1 country
- Photodynamic Therapy Versus Eplerenone: Treatment Trial for Chronic Central Serous ChorioretinopathyStatus unknownNCT03079141Phase 41 country
- Multimodal Imaging in Central Serous ChorioretinopathyTerminatedNCT02889185Not applicable1 country
- Micropulse 577nm Laser vs Traditional Laser Treatment in Central Serous ChorioretinopathyCompletedNCT02735213Phase 2/31 country
- Optical Coherence Tomography Angiography (OCT-A) and Central Serous Chorioretinopathy (CSC)CompletedNCT03950089
- Selective Retina Therapy With Real-Time Feedback-Controlled Dosimetry for Treating Acute Idiopathic Central Serous Chorioretinopathy in Korean PatientsCompletedNCT03339856Not applicable
- Selective Retina Therapy With 'R:GEN' in Patients With Central Serous ChorioretinopathyCompletedNCT03758963Not applicable1 country
- Eplerenone for the Treatment of Central Serous ChorioretinopathyCompletedNCT01990677Not applicable1 country
- The Changes of Retinal Capillaries After Half-dose PDT Measured by OCTA in Eyes With CSCStatus unknownNCT036921691 country
- Treatment Trial for Acute Central Serous ChorioretinopathyCompletedNCT02784665Not applicable1 country
- Brinzolamide for the Treatment of Chronic Central Serous ChorioretinopathyStatus unknownNCT03542006Phase 22 countries
- Eplerenone for Central Serous ChorioretinopathyCompletedNCT01822561Phase 21 country
- Effects of OCTA-guided PDT in Acute CSCCompletedNCT03497000Not applicable1 country
- Study on the Use of Micropulse Laser to Treat Central Serous ChorioretinopathyTerminatedNCT01982383Not applicable1 country
- Prospective Randomized Controlled Treatment Trial for Chronic Central Serous ChorioretinopathyCompletedNCT01797861Phase 44 countries