Atrial Fibrillation clinical trials
The registry lists 4,009 studies for Atrial Fibrillation across more than 10 countries. 960 are recruiting or about to start. 3,430 of them are mainly about Atrial Fibrillation (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 4,220 studies for Atrial Fibrillation. How that becomes 4,001 here
This page counts the studies the registry files under Atrial Fibrillation, and those it files under no condition that list Atrial Fibrillationthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 4,220Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −67List Atrial Fibrillation as a condition, but the registry did not file them under itMost often written as “Atrial Fibrillation Rapid” (11), “Non-valvular Atrial Fibrillation (NVAF)” (10), and “Non-valvular Atrial Fibrillation” (8). The registry filed them under other conditions only, most often Stroke (12) and Heart Failure (11).
- −152Match it another way140 name it in the title, 8 in a keyword, and 4 by a synonym or other text the search reads.
- 4,001The count on this page165 of them list Atrial Fibrillation in their own words; the registry filed them under no condition.
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Status
Who runs them
Abbott Medical Devices (66) · Bayer (64) · Boston Scientific Corporation (61) · Yonsei University (52) · Biosense Webster, Inc. (52) · Boehringer Ingelheim (45) · Beijing Anzhen Hospital (36) · Medtronic Cardiac Ablation Solutions (33)
What is being tested here
Drugs under test in Atrial Fibrillation studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Amiodarone | 10 | 10 | 41 |
| Apixaban | 10 | 12 | 29 |
| Rivaroxaban | 8 | 17 | 44 |
| Edoxaban | 5 | 11 | 27 |
| Dapagliflozin | 5 | 3 | 8 |
| Tirzepatide | 4 | 0 | 4 |
| Colchicine | 3 | 12 | 18 |
| Aspirin | 3 | 6 | 17 |
| Flecainide | 3 | 3 | 13 |
| Semaglutide | 3 | 2 | 6 |
Drug classes tested here Factor Xa inhibitors 21 open · Potassium channel blockers 10 open · SGLT2 inhibitors 8 open · GLP-1 receptor agonists 7 open · Beta blockers 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Effect of Dapagliflozin on the Recurrence of Atrial Tachyarrhythmia in Patients Undergoing Catheter Ablation of Atrial Fibrillation · Phase 3 · Chang Gung Memorial Hospital
- Dec 2026Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR · Phase 3 · Wake Forest University Health Sciences
- Dec 2026A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation · Phase 3 · Janssen Research & Development, LLC
- Jan 2027BiodEgradable Soaked Amiodarone paTch Use for the Prevention of Atrial Fibrillation After Cardiac Surgery · Phase 3 · Jilin Heart Hospital
- Mar 2027Colchicine After Electrocardioversion for Atrial Fibrillation · Phase 3 · University Hospital, Basel, Switzerland
- Apr 2027Anticoagulation in ICH Survivors for Stroke Prevention and Recovery · Phase 3 · Yale University
- Apr 2027Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF) · Phase 3 · University of Oklahoma
- Apr 2027Amiodarone and N-Acetylcysteine or Amiodarone Alone for Preventing Atrial Fibrillation After Thoracic Surgery · Phase 3 · Memorial Sloan Kettering Cancer Center
- Oct 2027SGB for Prevention of Postop A-Fib After Cardiac SurgeryTrial · Phase 3 · The Cleveland Clinic
- Oct 2027Safety and Efficacy of Apixaban Versus Warfarin in Peritoneal Dialysis Patients With Non Valvular Atrial Fibrillation: a Prospective, Randomised, Open-label, Blinded End-point Trial (APIDP2) · Phase 3 · University Hospital, Caen
Who these studies take
Of the 611 Atrial Fibrillation studies recruiting now, 407 (67%) set no upper age limit and 43 (7%) stop at 75 or younger. 21 (3%) take children under 18. 1 (<1%) are for women only and 2 (<1%) for men only; 43 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 16 (3%) | 16 (3%) |
| 18 | 500 (82%) | 500 (82%) |
| 30 | 561 (92%) | 561 (92%) |
| 40 | 568 (93%) | 569 (93%) |
| 50 | 571 (93%) | 573 (94%) |
| 65 | 596 (98%) | 596 (98%) |
| 75 | 592 (97%) | 591 (97%) |
| 85 | 486 (80%) | 485 (79%) |
Across all 4,009 studies, recruiting or not: 10% stop at 75 or younger and 2% at 65; 5% take children; <1% are for women only and <1% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Atrial Fibrillation studies take
Of 141 phase 4 interventional studies under Atrial Fibrillation, half reached primary completion within 48 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 11 mo3–20 · 20 studies | — | — |
| Phase 2 | 32 mo18–39 · 41 studies | — | — |
| Phase 3 | 42 mo32–63 · 83 studies | — | 56 mo32–73 · 62 studies |
| Phase 4 | 48 mo27–81 · 141 studies | — | 53 mo28–81 · 129 studies |
| Interventional, no phase | 33 mo18–54 · 1,050 studies | 22 mo12–36 · 255 studies | 39 mo21–59 · 795 studies |
| Observational | 38 mo22–76 · 698 studies | 26 mo14–42 · 148 studies | 46 mo25–91 · 550 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting12
- A Study of Varipulse Catheter in Participants With Paroxysmal Atrial Fibrillation Under Optimized SedationNov 4, 2026NCT07511166
- A Study of Dual Energy THERMOCOOL SMARTTOUCH™ SF Catheter With TRUPULSE™ Generator in Persistent Atrial FibrillationNov 4, 2026NCT07845682
- AI-Based Cardiac Analysis Using 12-Lead and 1-Lead ECGOct 30, 2026NCT07844434
- Posterior Mitral Isthmus Line With Vein of Marshall Ethanolisation Compared With Anterior Mitral Lines in Patients With Persistent Atrial FibrillationOct 26, 2026NCT06962176
- Association Between Circulating BDNF Levels and Atrial Cardiomyopathy in Patients Undergoing Ablation for Persistent Atrial FibrillationOct 26, 2026NCT07648329
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- Globe Registry: Globe® Pulsed Field System Registry Study for Treating Patients With Symptomatic Atrial FibrillationOct 26, 2026NCT07651852
- Reliability of Multiple-Repetition-Maximum Tests in Patients With Cardiovascular Disease or Risk FactorsOct 22, 2026NCT06796582
- Bundle Branch Pacing to Preserve Ejection Fraction in Atrial Fibrillation TrialOct 19, 2026NCT07759700
- Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)Oct 16, 2026NCT07095634
- BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial Fibrillation and Cerebral AtherosclerosisOct 16, 2026NCT07237308
- Elite AF IDE Trial (Elite AF)Oct 16, 2026NCT07287436
- Optimal Shock Energy for Electrical Cardioversion of Atrial FibrillationOct 13, 2026NCT07610980
Results posted3
- Long-term Outcomes After Percutaneous Closure of PFOOct 29, 2026NCT05558774
- Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)Oct 16, 2026NCT03310125
- Data-driven SDM to Reduce Symptom Burden in AFOct 15, 2026NCT04993807
Stopped3
- Bariatric Surgery Evaluation and Assessment of Treatment Efficacy - Intervention TrialTerminatedNov 12, 2026NCT06065124
- Post Intensive Care Unit Atrial FibrillationTerminatedOct 22, 2026NCT05860894
- Peripheral Nerve Stimulation Therapy for Atrial FibrillationTerminatedOct 21, 2026NCT05653583
Newly registered35
- Pulsed Field Ablation for Atrial Fibrillation Under General Anesthesia Versus Remimazolam-based Deep SedationNov 10, 2026NCT07927582
- A Nurse-led Structured Risk Factor Management Programme to Improve Quality of Life for Patients With Atrial FibrillationNov 10, 2026NCT07929259
- LATAM AF Ablation RegistryNov 9, 2026NCT07924202
- AI-Based Tools for Stroke Diagnosis, Treatment and Outcome Prediction: a Multicentre Prospective Observational StudyNov 9, 2026NCT07924371
- The Evaluation of User Experience With FARAVIEW™ Technology of the OPAL HDx™ Mapping System When Used With the FARAWAVE NAV™ ULTRA Pulsed Field Ablation Catheter in the Treatment of Atrial FibrillationNov 9, 2026NCT07925359
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- Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After Electrophysiology Procedures (GLUE-EP)Nov 9, 2026NCT07926191
- Unipolar Voltage-Guided Substrate Modification Plus Pulsed Field Ablation Pulmonary Vein Isolation Versus Pulmonary Vein Isolation Alone in Persistent Atrial FibrillationNov 9, 2026NCT07926854
- From Skull Base to Atrial Fibrillation: Reduced Jugular Foramen Volume as a Structural Correlate of Atrial FibrillationNov 6, 2026NCT07922655
- Sacubitril/Valsartan vs Standard Treatment for Preventing Atrial Fibrillation Recurrence After Catheter Ablation in Persistent Atrial Fibrillation Patients With Without HypertensionNov 2, 2026NCT07910058
- Structured Treatment and Resource Efficiency Assessment With Lean Six Sigma Integration for Pulmonary Vein IsolationNov 2, 2026NCT07910370
- Paroxysmal Atrial Fibrillation Repeat Ablation Strategies With Durably Isolated Pulmonary VeinsNov 2, 2026NCT07910825
- Pulsed Field Ablation of Atrial Fibrillation: CENTAURI Versus FARAPULSEOct 29, 2026NCT07902739
- A Comparison of Beta-blockers and Calcium Channel Blockers in Atrial FibrillationOct 29, 2026NCT07904507
- CATCH AF - Atrial Fibrillation Detection in Cryptogenic StrokeOct 28, 2026NCT07899788
- Dual-Energy Lattice-Tip Assisted Marshall-Plan Strategy in Redo Persistent Atrial Fibrillation AblationOct 28, 2026NCT07899918
- A Comparison of Pulsed Field Ablation (PFA) vs Cryoablation for Atrial Fibrillation Under Deep SedationOct 28, 2026NCT07900685
- Resumption of Anticoagulation After Major Gastrointestinal Bleeding in Patients With Atrial FibrillationOct 28, 2026NCT07901699
- Mobile Clinic-Supported, Village Doctor-Led Screening and Integrated Care for Atrial Fibrillation and Heart Failure Comorbidity in Rural China (MOVE-AF HF)Oct 27, 2026NCT07896863
- Mazdutide for Reducing Atrial Fibrillation Recurrence After Catheter Ablation in Obese PatientsOct 27, 2026NCT07897305
- Renal Denervation in Patients With Atrial Fibrillation and HypertensionOct 26, 2026NCT07893821
- Pilot Study to Determine the Optimal Protocol for Preoperative Transcutaneous Vagal NeurostimulationOct 23, 2026NCT07891390
- SGB for Prevention of Postop A-Fib After Cardiac SurgeryTrialOct 23, 2026NCT07893275
- Conduction Breakthrough in the Coronary Sinus Post Endocardial Mitral Isthmus AblationOct 22, 2026NCT07889440
- Randomized Interventional Clinical Trial on the Prevention of Atrial Fibrillation Using Colchicine, Amiodarone And a Posterior Pericardiotomy.Oct 21, 2026NCT07887022
- Comparison of Two Pulse Field Ablation Systems for AF AblationOct 20, 2026NCT07883629
- Energy Dose and Cardioversion Outcomes in AFOct 20, 2026NCT07884253
- Efficacy and Safety of Individualized Pulsed Field Ablation Guided by Pulmonary Vein Antral Substrate Mapping for Atrial FibrillationOct 19, 2026NCT07880262
- Sevoflurane Versus Propofol Anesthesia in Intracardiac Echocardiography-Guided Atrial Fibrillation AblationOct 16, 2026NCT07877116
- Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial FibrillationOct 16, 2026NCT07877519
- A Real World Evidence Retrospective Data Collection Study of Edoxaban and RivaroxabanOct 15, 2026NCT07874555
- Bachmann's Bundle Versus Right Atrial Appendage PacingOct 15, 2026NCT07874763
- CENTAURI Post-Market Clinical RegistryOct 14, 2026NCT07874048
- Cardiovascular Risk in Patients With Primary HyperparathyroidismOct 13, 2026NCT07870369
- Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in JapanOct 13, 2026NCT07870837
- Vortosiran in Atrial FibrillationOct 13, 2026NCT07870889
Studies
Recruiting first, then most recently updated. Showing 50 of 4,009. Browse all 4,009 → or search them.
- ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3RecruitingNCT06716021Phase 33 countries
- PULSED AF Post-Approval StudyRecruitingNCT065781043 countries
- A Nurse-led Structured Risk Factor Management Programme to Improve Quality of Life for Patients With Atrial FibrillationNot yet recruitingNCT07929259Not applicable1 country
- Inhaled Hydrogen Therapy's Effect on Early Recurrences of Atrial Fibrillation Post-ablation.Not yet recruitingNCT07928622Phase 21 country
- Pulsed Field Ablation for Atrial Fibrillation Under General Anesthesia Versus Remimazolam-based Deep SedationNot yet recruitingNCT07927582Not applicable
- Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is UnsuitableRecruitingNCT07430956Phase 32 countries
- Alert-HF: Early Detection and Intervention on Atrial Fibrillation in Heart Failure PatientsNot yet recruitingNCT07816458Not applicable1 country
- Intracardiac Echocardiography Guided Watchman Device ImplantRecruitingNCT06007872Not applicable1 country
- Evaluation of the Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal Atrial FibrillationNot yet recruitingNCT07714876Not applicable1 country
- Ablation of Focal Activation in Atrial FibrillationRecruitingNCT06402617Not applicable1 country
- AI-Based Tools for Stroke Diagnosis, Treatment and Outcome Prediction: a Multicentre Prospective Observational StudyRecruitingNCT079243716 countries
- Tissue Adhesive Versus Figure-of-Eight Suture for Femoral Venous Closure After Electrophysiology Procedures (GLUE-EP)Not yet recruitingNCT079261911 country
- Regulation of Platelet Function in Older Patients With Atrial FibrillationNot yet recruitingNCT07724301
- The Evaluation of User Experience With FARAVIEW™ Technology of the OPAL HDx™ Mapping System When Used With the FARAWAVE NAV™ ULTRA Pulsed Field Ablation Catheter in the Treatment of Atrial FibrillationNot yet recruitingNCT07925359Not applicable3 countries
- Unipolar Voltage-Guided Substrate Modification Plus Pulsed Field Ablation Pulmonary Vein Isolation Versus Pulmonary Vein Isolation Alone in Persistent Atrial FibrillationNot yet recruitingNCT07926854Not applicable1 country
- LATAM AF Ablation RegistryNot yet recruitingNCT07924202
- Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation TherapyRecruitingNCT05976685Not applicable6 countries
- Peer-Mentor Support for Vulnerable Patients With Atrial FibrillationRecruitingNCT07498283Not applicable1 country
- Stroke and Systemic Embolism Prevention in Adult Participants With Atrial FibrillationRecruitingNCT07626411Phase 33 countries
- Hummingbird ICE StudyNot yet recruitingNCT075522721 country
- Safety in Adult Participants With Atrial Fibrillation Who Are Treated With AnticoagulationRecruitingNCT07175428Phase 24 countries
- A Study of Dual Energy THERMOCOOL SMARTTOUCH™ SF Catheter With TRUPULSE™ Generator in Persistent Atrial FibrillationRecruitingNCT07845682Not applicable1 country
- A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter SystemRecruitingNCT07227532Not applicable1 country
- A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping CatheterRecruitingNCT07116525Not applicable3 countries
- Sacubitril/Valsartan vs Standard Treatment for Preventing Atrial Fibrillation Recurrence After Catheter Ablation in Persistent Atrial Fibrillation Patients With Without HypertensionNot yet recruitingNCT07910058Phase 4
- A Study of Varipulse Catheter in Participants With Paroxysmal Atrial Fibrillation Under Optimized SedationRecruitingNCT075111661 country
- Atrial Fibrillation Patients Treated With Catheter AblationRecruitingNCT052661441 country
- A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava IsolationRecruitingNCT07527299Not applicable1 country
- A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial FibrillationRecruitingNCT07523750Not applicable1 country
- Anatomical Navigation for Guided Electrophysiology in AFL and AFibRecruitingNCT07210151Not applicable3 countries
- Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation ProceduresRecruitingNCT07271238Not applicable1 country
- Registry on Luma Vision's VERAFEYE System (ENLIgHT)Not yet recruitingNCT06293430
- Paroxysmal Atrial Fibrillation Repeat Ablation Strategies With Durably Isolated Pulmonary VeinsNot yet recruitingNCT07910825Not applicable1 country
- The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial FibrillationRecruitingNCT05836987Phase 31 country
- A Study to Predict Atrial Fibrillation (AF) Burden in Participants With PAF and PsAF Treated With the VARIPULSE™ PFA CatheterNot yet recruitingNCT07788989Not applicable
- Catheter Ablation Using a Novel Navigation and Imaging SystemNot yet recruitingNCT06895187
- Structured Treatment and Resource Efficiency Assessment With Lean Six Sigma Integration for Pulmonary Vein IsolationRecruitingNCT07910370Not applicable1 country
- AI-Based Cardiac Analysis Using 12-Lead and 1-Lead ECGRecruitingNCT078444341 country
- Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or VenetoclaxRecruitingNCT057241211 country
- A Comparison of Beta-blockers and Calcium Channel Blockers in Atrial FibrillationNot yet recruitingNCT07904507Phase 41 country
- CATCH AF - Atrial Fibrillation Detection in Cryptogenic StrokeNot yet recruitingNCT07899788Not applicable1 country
- A Comparison of Pulsed Field Ablation (PFA) vs Cryoablation for Atrial Fibrillation Under Deep SedationRecruitingNCT07900685Not applicable1 country
- Dual-Energy Lattice-Tip Assisted Marshall-Plan Strategy in Redo Persistent Atrial Fibrillation AblationNot yet recruitingNCT07899918Not applicable1 country
- A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial FibrillationRecruitingNCT07217067Phase 27 countries
- BOdygUardian MOnitoriNg for ReCurrencE of AFRecruitingNCT076716771 country
- Mazdutide for Reducing Atrial Fibrillation Recurrence After Catheter Ablation in Obese PatientsNot yet recruitingNCT07897305Not applicable1 country
- SGB for Prevention of Postop A-Fib After Cardiac SurgeryTrialNot yet recruitingNCT07893275Phase 3
- OPTION-EMEA Clinical TrialRecruitingNCT07349121Not applicable5 countries
- Mobile Clinic-Supported, Village Doctor-Led Screening and Integrated Care for Atrial Fibrillation and Heart Failure Comorbidity in Rural China (MOVE-AF HF)Not yet recruitingNCT07896863Not applicable1 country
- Intracardiac Echocardiography Catheter Supply-Chain Reliability and Clinical Access StudyEnrolling by invitationNCT077880401 country