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Essential Hypertension clinical trials

The registry lists 478 studies for Essential Hypertension across more than 10 countries. 74 are recruiting or about to start. 411 of them are mainly about Essential Hypertension (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Isolated Systolic Hypertension too: 510 studies, 80 open.

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Status

Completed
321
Status unknown
62
Recruiting
43
Not yet recruiting
27
Active, not recruiting
12
Terminated
8

Phase

Phase 3
126
Phase 4
64
Phase 1
55
Phase 2
50
Early Phase 1
3

Where

Korea, Republic of
98
China
75
United States
53
Germany
35
Japan
27
Italy
23

Who runs them

Boryung Pharmaceutical Co., Ltd (44) · Chong Kun Dang Pharmaceutical (18) · Takeda (15) · Novartis Pharmaceuticals (15) · Novartis (12) · Bayer (9) · Daiichi Sankyo (9) · Addpharma Inc. (8)

What is being tested here

Drugs under test in Essential Hypertension studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
BR1015408
Valsartan2510
Amlodipine11933
Hydrochlorothiazide11117
Olmesartan11215
Telmisartan116
Sacubitril123
AD-209113
Irbesartan113
Eplerenone113

Drug classes tested here Angiotensin receptor blockers (ARBs) 5 open · Calcium channel blockers 1 open · Diuretics 1 open · Thiazide diuretics 1 open · Mineralocorticoid receptor antagonists (MRAs) 1 open

Coming up

9phase 3 studies under way
18studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 43 Essential Hypertension studies recruiting now, 15 (35%) set no upper age limit and 20 (47%) stop at 75 or younger. 4 (9%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 11 (26%) take healthy volunteers.

Recruiting studies that take each age, of 43
AgeWomenMen
104 (9%)4 (9%)
1825 (58%)25 (58%)
3037 (86%)37 (86%)
4038 (88%)38 (88%)
5039 (91%)39 (91%)
6539 (91%)39 (91%)
7531 (72%)31 (72%)
8519 (44%)19 (44%)

Across all 478 studies, recruiting or not: 45% stop at 75 or younger and 23% at 65; 5% take children; 1% are for women only and 5% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Essential Hypertension studies take

Of 47 phase 3 interventional studies under Essential Hypertension, half reached primary completion within 17 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 12 mo1–8 · 18 studies——
Phase 217 mo9–40 · 15 studies——
Phase 317 mo11–24 · 47 studies16 mo11–24 · 45 studies—
Phase 424 mo18–36 · 22 studies——
Interventional, no phase20 mo8–48 · 80 studies—16 mo7–47 · 70 studies
Observational44 mo27–52 · 26 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting1

Newly registered3

Studies

Recruiting first, then most recently updated. Showing 50 of 478. Browse all 478 → or search them.