Polycystic Ovary Syndrome clinical trials
The registry lists 958 studies for Polycystic Ovary Syndrome across more than 10 countries. 176 are recruiting or about to start. 830 of them are mainly about Polycystic Ovary Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.
ClinicalTrials.gov finds 1,078 studies for Polycystic Ovary Syndrome. How that becomes 956 here
This page counts the studies the registry files under Polycystic Ovary Syndrome, and those it files under no condition that list Polycystic Ovary Syndromethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,078Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −4List Polycystic Ovary Syndrome as a condition, but the registry did not file them under itMost often written as “Polycystic Ovarian Syndrome in Adolescent Females” (2), “Anovulatory Infertility Related to Polycystic Ovary Syndrome” (1), and “Polycystic Ovarian Syndrome Females” (1). The registry filed them under other conditions only, most often Anovulation (1) and Infertility (1).
- −118Match it another way112 name it in the title and 6 by a synonym or other text the search reads.
- 956The count on this page2 of them list Polycystic Ovary Syndrome in their own words; the registry filed them under no condition.
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Status
Who runs them
Cairo University (34) · University of Virginia (25) · University Magna Graecia (16) · Assiut University (14) · Peking University Third Hospital (13) · Shanghai 10th People's Hospital (12) · Ain Shams University (12) · Taipei Medical University WanFang Hospital (11)
What is being tested here
Drugs under test in Polycystic Ovary Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Metformin | 9 | 21 | 114 |
| Inositol | 5 | 4 | 33 |
| Spironolactone | 4 | 0 | 7 |
| Progesterone | 3 | 1 | 12 |
| Semaglutide | 3 | 3 | 5 |
| Folic Acid | 2 | 0 | 14 |
| Liraglutide | 2 | 3 | 6 |
| Carnitine | 2 | 0 | 5 |
| GLP-1 Mimetic | 2 | 0 | 2 |
| Dehydroepiandrosterone | 2 | 0 | 2 |
Drug classes tested here GLP-1 receptor agonists 6 open · Mineralocorticoid receptor antagonists (MRAs) 4 open · Progestins 3 open · SGLT2 inhibitors 2 open · Estrogens 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Sep 2027Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome · Phase 3 · University Hospital, Lille
- Nov 2026Evaluation of Fibromyalgia Frequency and Pain Parameters in Women With Polycystic Ovary Syndrome · Ufuk University
- Nov 2026Ovary Syndrome for Efficient Diagnosis and Targeted Therapy · Asian Institute of Gastroenterology, India
- Dec 2026Myo-Inositol for Infertility in PCOS · University of Oklahoma
- Dec 2026Brown Adipose Tissue Modulation in Polycystic Ovary Syndrome Using Infrared Thermography · Istanbul Health and Technology University
- Dec 2026Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot · Ohio State University
- Dec 2026Polycystic Ovarian Syndrome (PCOS) Biomarker Evaluation Study · University Hospital Erlangen
- Dec 2026Clinical Research Cohort for Polycystic Ovary Syndrome · Guangdong Women and Children Hospital
- Dec 2026IVF\ICSI Outcome in Women With Polycystic Ovary Syndrome · Egymedicalpedia
- Dec 2026Inspiratory Muscle Training for the Management of Polyendocrine Metabolic Ovarian Syndrome · British University In Egypt
Who these studies take
Of the 119 Polycystic Ovary Syndrome studies recruiting now, 11 (9%) set no upper age limit and 105 (88%) stop at 75 or younger. 23 (19%) take children under 18. 107 (90%) are for women only and 0 (0%) for men only; 41 (34%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 14 (12%) | 2 (2%) |
| 18 | 94 (79%) | 12 (10%) |
| 30 | 106 (89%) | 12 (10%) |
| 40 | 88 (74%) | 12 (10%) |
| 50 | 23 (19%) | 7 (6%) |
| 65 | 17 (14%) | 6 (5%) |
| 75 | 14 (12%) | 6 (5%) |
| 85 | 12 (10%) | 6 (5%) |
Across all 958 studies, recruiting or not: 94% stop at 75 or younger and 94% at 65; 15% take children; 97% are for women only and <1% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Polycystic Ovary Syndrome studies take
Of 42 phase 4 interventional studies under Polycystic Ovary Syndrome, half reached primary completion within 25 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 52 mo9–147 · 27 studies | — | — |
| Phase 2 | 17 mo10–29 · 23 studies | — | — |
| Phase 2/3 | 12 mo8–26 · 13 studies | — | — |
| Phase 3 | 28 mo11–48 · 26 studies | — | 28 mo11–48 · 26 studies |
| Phase 4 | 25 mo11–45 · 42 studies | — | 25 mo8–45 · 41 studies |
| Interventional, no phase | 18 mo7–37 · 218 studies | — | 18 mo7–37 · 203 studies |
| Observational | 14 mo6–48 · 74 studies | — | 14 mo6–47 · 71 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting2
Results posted1
- Inositol Supplementation to Treat PCOS (INSUPP-PCOS)Oct 28, 2026NCT03864068
Newly registered11
- Effects of Pilates Exercises on Doppler Parameters in Obese Females With Polycystic Ovarian SyndromeNov 13, 2026NCT07937202
- Myo-Inositol and D-Chiro-Inositol Versus Metformin for Treating Anovulation in Women With Polycystic Ovary SyndromeNov 12, 2026NCT07931625
- Efficacy of Ovarian Drilling Via vNOTES Laparoscopy in Patients With PCOSNov 6, 2026NCT07923552
- The Value of LC-MS/MS Detection of Androgen Profiles in the Diagnosis of PCOS: A Prospective, Multicenter Real-world StudyNov 4, 2026NCT07916909
- Effect of Combined Hormonal Contraceptiveson Free Androgen Index (FAI) in Polycystic Ovary Syndrome:Drospirenone-Ethinyl Estradiol (DRSP-EE) Versus Cyproterone Acetate-Ethinyl Estradiol (CPA-EE)Nov 3, 2026NCT07911709
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- Brown Adipose Tissue Modulation in Polycystic Ovary Syndrome Using Infrared ThermographyOct 27, 2026NCT07896642
- Association Between Polycystic Ovary Syndrome and Sleep Quality: A Questionnaire-Based StudyOct 27, 2026NCT07898423
- Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity RisksOct 21, 2026NCT07884903
- The Effect of Lifestyle Program Women With PCOSOct 19, 2026NCT07880366
- Efficacy of Metformin With and Without Probiotics in Women With PCOSOct 15, 2026NCT07874646
- High Intensity Interval Training Versus Mat Pilates in Women With PCOSOct 15, 2026NCT07875400
Studies
Recruiting first, then most recently updated. Showing 50 of 958. Browse all 958 → or search them.
- Effects of Pilates Exercises on Doppler Parameters in Obese Females With Polycystic Ovarian SyndromeNot yet recruitingNCT07937202Not applicable1 country
- Brown Adipose Tissue Modulation in Polycystic Ovary Syndrome Using Infrared ThermographyRecruitingNCT07896642Not applicable1 country
- Investigation of the Effectiveness of Spinal Stabilization Exercises Added to Aerobic Exercise in Women With Polycystic Ovary SyndromeEnrolling by invitationNCT07871851Not applicable1 country
- Fecal Microbiota Transplantation for Obese Women With Polyendocrine Metabolic Ovarian SyndromeRecruitingNCT07746635Not applicable1 country
- Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Women With PCOS Undergoing PGT-ANot yet recruitingNCT05326087Phase 3
- Efficacy of Ovarian Drilling Via vNOTES Laparoscopy in Patients With PCOSRecruitingNCT07923552Not applicable1 country
- The Value of LC-MS/MS Detection of Androgen Profiles in the Diagnosis of PCOS: A Prospective, Multicenter Real-world StudyRecruitingNCT079169091 country
- The Effects of the Mediterranean Diet and Synbiotics in Polycystic Ovary SyndromeRecruitingNCT07342946Not applicable1 country
- Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity RisksNot yet recruitingNCT078849031 country
- Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for PCOSRecruitingNCT06143527Phase 12 countries
- Time-Restricted Eating as a Dietary Intervention for Polyendocrine Metabolic Ovarian Syndrome (PMOS): Protocol for a Randomized Controlled TrialNot yet recruitingNCT06204965Not applicable1 country
- Nutrition Intervention for Women With Polycystic Ovary SyndromeEnrolling by invitationNCT07298603Not applicable1 country
- Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOSRecruitingNCT07770711Not applicable1 country
- High Intensity Interval Training Versus Mat Pilates in Women With PCOSNot yet recruitingNCT07875400Not applicable1 country
- PMOS in OSA Pilot StudyRecruitingNCT07871149Not applicable1 country
- Continuous Glucose Monitoring in Polycystic Ovarian SyndromeRecruitingNCT073924761 country
- Metabolic and Hormonal Parameters in Women With Polyendocrine Metabolic Ovarian SyndromeNot yet recruitingNCT07844785
- Use of tDCS Stimulation in Neurological and Gynaecological ConditionsRecruitingNCT06891690Not applicable1 country
- EHBM-Based Intervention for Polycystic Ovarain Syndrome Among High Female School StudentsNot yet recruitingNCT07780214Not applicable1 country
- Multimodal Ocular Diagnosis-Guided Precision Acupuncture and Lifestyle Intervention for PCOSRecruitingNCT07809503Not applicable1 country
- Acupuncture for Insulin Resistance in Women With Polycystic Ovary SyndromeNot yet recruitingNCT07806656Not applicable1 country
- Polycystic Ovary Syndrome in Type 1 DiabetesRecruitingNCT074909641 country
- Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary SyndromeRecruitingNCT05819853Phase 31 country
- Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)RecruitingNCT07780188Not applicable1 country
- PCOS and Brain HealthRecruitingNCT077275121 country
- This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.RecruitingNCT07764328Not applicable1 country
- Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)RecruitingNCT07412028Not applicable1 country
- Effect of Orlistat on Metabolic and Hormonal Features in Women With Polycystic Ovary Syndrome (PCOS): a Randomized Controlled Clinical TrialRecruitingNCT07747909Not applicable1 country
- Comparison of IVF Outcomes Between PPOS and Antagonist Protocols in Women With PCOSRecruitingNCT07394530Not applicable1 country
- Evaluation of Serum Preptin Levels in Patients With Polycystic Ovary SyndromeNot yet recruitingNCT07736079
- Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS)Not yet recruitingNCT077313731 country
- Construction of a Multi-dimensional Risk Assessment System: a Clinical Study of Polycystic Ovary Syndrome Complicated With ThrombophiliaRecruitingNCT075710961 country
- Effect of High Intensity Interval Training on Insulin Resistance in Polycystic Ovarian SyndromeNot yet recruitingNCT07708766Not applicable1 country
- Diaphragmatic Breathing Exercises on Sleep Disorders un Polycystic Ovarian SyndromeRecruitingNCT07698925Not applicable1 country
- Effects of GLP-1RAs on Fertility Outcomes in Obese Women With PCOSNot yet recruitingNCT07687667Not applicable1 country
- Assessment of Metabolic Changes in Response to Glcuose Intake in Women With Polyendocrine Metabolic Ovarian Syndrome (PMOS)Not yet recruitingNCT07687264Not applicable1 country
- Physical Activity and Cardiometabolic Health in Women With or Without Polycystic Ovary Syndrome (SCOPAP)Not yet recruitingNCT07659392Not applicable1 country
- Exercise Programs in Women With PCOSNot yet recruitingNCT07509762Not applicable1 country
- Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Polycystic Ovarian Syndrome.RecruitingNCT07645014Not applicable1 country
- Fertility and Polycystic Ovary SyndromeNot yet recruitingNCT074995181 country
- Myo-Inositol Alone Versus Myo-Inositol Plus Alpha-Lactalbumin in Women With Polycystic Ovary SyndromeNot yet recruitingNCT07629895Not applicable1 country
- Theta Healing-Based Intervention in Women With Polycystic Ovary SyndromeNot yet recruitingNCT07630441Not applicable1 country
- MeDiApp-PCOS: A Mobile Mediterranean Diet App for Women With Polycystic Ovary SyndromeNot yet recruitingNCT07598344Not applicable
- Observational Study on the Causal Architecture of Polycystic Ovary Syndrome (PCOS)Not yet recruitingNCT07623551
- Combined Oral Contraceptive Pill and Resistance StarchRecruitingNCT06852365Phase 21 country
- Efficacy of a GLP-1/FGF21 Dual Agonist for Treating PCOSRecruitingNCT07616037Phase 21 country
- Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid HypofunctionRecruitingNCT07591246Not applicable1 country
- Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation PilotRecruitingNCT07227363Not applicable1 country
- Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS DiagnosisRecruitingNCT059502821 country
- Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian SyndromeRecruitingNCT03059173Phase 31 country