Diabetic Nephropathies clinical trials
The registry lists 543 studies for Diabetic Nephropathies across more than 10 countries. 110 are recruiting or about to start. 383 of them are mainly about Diabetic Nephropathies (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 761 studies for Diabetic Nephropathies. How that becomes 543 here
This page counts the studies the registry files under Diabetic Nephropathies, and those it files under no condition that list Diabetic Nephropathiesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 761Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −13List Diabetic Nephropathies as a condition, but the registry did not file them under itMost often written as “Diabetic Nephropathy Type 2” (6), “Macroalbuminuric Diabetic Nephropathy” (1), and “Type 2 Diabetes Mellitus With Established Diabetic Nephropathy” (1). The registry filed them under other conditions only, most often Diabetes Mellitus, Type 2 (6) and Renal Insufficiency, Chronic (4).
- −205Match it another way52 name it in the title, 2 in a keyword, and 151 by a synonym or other text the search reads.
- 543The count on this page26 of them list Diabetic Nephropathies in their own words; the registry filed them under no condition.
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Status
Who runs them
Assiut University (25) · University of Colorado, Denver (11) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (10) · Steno Diabetes Center Copenhagen (9) · Tanta University (8) · Bayer (8) · Mitsubishi Tanabe Pharma Corporation (6) · Boehringer Ingelheim (6)
What is being tested here
Drugs under test in Diabetic Nephropathies studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Finerenone | 4 | 3 | 9 |
| Empagliflozin | 2 | 4 | 10 |
| Dapagliflozin | 2 | 1 | 6 |
| Sotagliflozin | 2 | 1 | 2 |
| Lisinopril | 1 | 1 | 6 |
| Telmisartan | 1 | 1 | 5 |
| Enalapril | 1 | 0 | 3 |
| Diosuxentan | 1 | 0 | 2 |
| Isuzinaxib | 1 | 0 | 2 |
| Semaglutide | 1 | 1 | 2 |
Drug classes tested here SGLT2 inhibitors 6 open · Mineralocorticoid receptor antagonists (MRAs) 4 open · Angiotensin receptor blockers (ARBs) 1 open · ACE inhibitors 1 open · Endothelin receptor antagonists 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jan 2027Study of the Protective Effect of Low-dose Aspirin on Renal Function in Patients With Early Diabetic Nephropathy · Phase 3 · Second Affiliated Hospital, School of Medicine, Zhejiang University
- May 2027"Dapagliflozin vs Dapagliflozin-Finerenone for Albuminuria in CKD With Type 2 Diabetes" · Phase 3 · Chittagong Medical College
- Oct 2027Vitamin D in Diabetic Neuropathy · Phase 3 · Tanta University
- Nov 2026Diabetic Nephropathy, Glycemic Control and Pseudophakic Macular Edema After Cataract Surgery · Thammasat University Hospital
- Nov 2026Decision Impact Trial of KidneyIntelX · Renalytix AI, Inc.
- Nov 2026Multidimensional Accurate Diagnosis and Treatment Technology and Clinical Transformation of Type 2 Diabetes Nephropathy · Chinese PLA General Hospital
- Nov 2026NAD Augmentation in Diabetes Kidney Disease · Brigham and Women's Hospital
- Nov 2026Effects and Safety of Diabetic GUideline Algorithm Implementation Performed by Primary Care Physicians in the Community · Shanghai Zhongshan Hospital
- Dec 2026Formoterol in Diabetes · Medical University of South Carolina
- Dec 2026The Intelligent Prevention And Control System And Strategy For The Whole Disease Cycle Of Diabetic Nephropathy · Chinese PLA General Hospital
Who these studies take
Of the 50 Diabetic Nephropathies studies recruiting now, 23 (46%) set no upper age limit and 16 (32%) stop at 75 or younger. 5 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 8 (16%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (6%) | 3 (6%) |
| 18 | 38 (76%) | 38 (76%) |
| 30 | 45 (90%) | 45 (90%) |
| 40 | 46 (92%) | 46 (92%) |
| 50 | 46 (92%) | 46 (92%) |
| 65 | 47 (94%) | 47 (94%) |
| 75 | 42 (84%) | 42 (84%) |
| 85 | 26 (52%) | 26 (52%) |
Across all 543 studies, recruiting or not: 43% stop at 75 or younger and 15% at 65; 6% take children; <1% are for women only and 1% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Diabetic Nephropathies studies take
Of 52 phase 2 interventional studies under Diabetic Nephropathies, half reached primary completion within 21 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 19 mo11–37 · 20 studies | — | — |
| Phase 2 | 21 mo13–31 · 52 studies | 20 mo14–28 · 32 studies | — |
| Phase 3 | 54 mo25–65 · 16 studies | — | — |
| Phase 4 | 33 mo21–42 · 21 studies | — | — |
| Interventional, no phase | 23 mo11–37 · 50 studies | — | 23 mo10–37 · 49 studies |
| Observational | 67 mo25–… · 38 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Results posted1
- A Pilot Study of Fenofibrate to Prevent Kidney Function Loss in Type 1 DiabetesNov 10, 2026NCT04929379
Newly registered5
- Beta-2-Trace Protein in Diabetic NephropathyNov 5, 2026NCT07919795
- A Study on the Safety and Clinical Efficacy of Guominkang in the Treatment of Diabetic Kidney DiseaseOct 30, 2026NCT07907965
- Modulatory Effects of Resveratrol Supplement Along With and Without Low Glycemic Index Diet Among Obese Patients With Diabetic NephropathyOct 23, 2026NCT07891975
- Impact of AI-Based Breath Ammonia Kidney Function Results on Clinical Pharmacist Medication RecommendationsOct 22, 2026NCT07888855
- Wearable NH₃ Sensor for Remote Non-invasive Monitoring and Diagnosis of Diabetic Kidney DiseaseOct 15, 2026NCT07875010
Studies
Recruiting first, then most recently updated. Showing 50 of 543. Browse all 543 → or search them.
- A Study to Investigate Safety, Tolerability, PK, and PD of AZD4248 in Healthy Participants, Participants With CKD and Type 2 Diabetes, Assess Home Measurements of Creatinine in a Non-Interventional Cohort, and Assess the Effect of AZD4248 on the PK of Midazolam and Metformin in Healthy ParticipantsRecruitingNCT07024823Phase 11 country
- QUARTET-DKD: Quadruple Therapy for Type 2 Diabetic NephropathyRecruitingNCT07775846Phase 41 country
- Beta-2-Trace Protein in Diabetic NephropathyNot yet recruitingNCT07919795
- Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney DiseaseRecruitingNCT07271186Phase 21 country
- Impact of AI-Based Breath Ammonia Kidney Function Results on Clinical Pharmacist Medication RecommendationsNot yet recruitingNCT078888551 country
- Modality Choice Before and After Failure for the Treatment of Painful Diabetic NeuropathyNot yet recruitingNCT07795593Phase 41 country
- dApagliflozin SC0062 and Prevention of Renal Injury; a Randomized EvaluationNot yet recruitingNCT06072326Phase 22 countries
- Clinical Predictors and Therapeutic Gaps in CKM Syndrome Among Adults With Type 2 DiabetesNot yet recruitingNCT078549901 country
- The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Disease.RecruitingNCT06600412Phase 21 country
- A Multicenter Randomized Double-Blind Trial of Chrocare CDSS for Integrated Management of Type 2 DiabetesNot yet recruitingNCT07833228Not applicable1 country
- Long-Term Follow-up Study of Participants Exposed to Renal Autologous Cell Therapy Frozen ProductEnrolling by invitationNCT067904981 country
- Human Umbilical Cord Mesenchymal Stem Cell Injection for Diabetic NephropathyRecruitingNCT07822152Phase 11 country
- Patients With Type 2 DiabetesRecruitingNCT072450821 country
- Role of Triglyceride-Glucose Index and Inflammatory Biomarkers as Prognostic Tools for Progression of Diabetic NephropathyNot yet recruitingNCT07813793
- Vitamin D in Diabetic NeuropathyNot yet recruitingNCT07644520Phase 2/3
- Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD)RecruitingNCT07434791Not applicable1 country
- A Long-Term Follow-Up Study of Participants Exposed to REACTRecruitingNCT059185231 country
- Role of Finerenone in African American Veterans With Diabetic Kidney DiseaseNot yet recruitingNCT07155694Phase 41 country
- Systemic Immune-Inflammation Index and Platelet Parameters in Diabetic Kidney DiseaseNot yet recruitingNCT07773467
- Human Umbilical Cord Mesenchymal Stem Cell Infusion for Type 2 Diabetic NephropathyNot yet recruitingNCT07769671Phase 1/21 country
- Lactoferrin Supplementation in Diabetic NephropathyRecruitingNCT07764991Phase 21 country
- Real World Evidence Clinical Utility Study of KidneyIntelXRecruitingNCT048023951 country
- DEL-1 and Thromboxane A2 in Diabetic Nephropathy PatientsNot yet recruitingNCT07749664
- Study of WAL0921 in Patients With Glomerular Kidney DiseasesRecruitingNCT06466135Phase 27 countries
- The Relationship Between Psychological Well-being, Social Support, and Disease Self-management in Patients With Diabetic NephropathyNot yet recruitingNCT077265891 country
- Finerenone for the Treatment of Type 2 Diabetes-Related Kidney Disease: Efficacy Observation and Related Factor AnalysisNot yet recruitingNCT07717697
- A Prospective Trial Of Oral Lead Chelation To Slow Renal Function Decline In Lead-Loaded Type 2 Diabetic Nephropathy PatientsNot yet recruitingNCT07709871Not applicable
- Intravenous Chelators in Lead-Burdened Type 2 Diabetic NephropathyNot yet recruitingNCT07706946Not applicable
- Evaluating the Effectiveness of a Smart Screening and Tiered Management Tool for Diabetic Kidney Disease in Primary Care: A Cluster Randomized TrialNot yet recruitingNCT07707518Not applicable1 country
- Safety and Efficacy of Mesenchymal Stromal Cells (Amimestrocel ) in Diabetic Kidney DiseaseRecruitingNCT06969807Phase 21 country
- Naoxintong Capsule for Diabetic Nephropathy With Dampness Retention Pattern: A Multicenter, Randomized, Double-Blind, Placebo-Controlled TrialAcronymNXT-DKDNot yet recruitingNCT07698223Phase 41 country
- Epithelial Dysmetabolism and Renal Fibrosis in ANCA VasculitisRecruitingNCT070102501 country
- Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney DiseaseRecruitingNCT07473323Phase 11 country
- Effect of Chinese Herbal Medicine on Renal Function in Diabetic Kidney DiseaseNot yet recruitingNCT07657351Not applicable1 country
- Mechanism of SGLT2 Inhibition in the KidneyRecruitingNCT06291155Phase 41 country
- Trial of Semaglutide for Diabetic Kidney Disease in Type 1 DiabetesRecruitingNCT05822609Phase 22 countries
- "Dapagliflozin vs Dapagliflozin-Finerenone for Albuminuria in CKD With Type 2 Diabetes"Not yet recruitingNCT07598864Phase 31 country
- Spironolactone Alternate Dosing vs Finerenone in Elevated Potassium - K Safety StudyNot yet recruitingNCT07523867Phase 4
- Multimodal Magnetic Resonance Imaging in Evaluation of Diabetic Kidney DiseaseRecruitingNCT064528621 country
- NAD Augmentation in Diabetes Kidney DiseaseRecruitingNCT05759468Phase 21 country
- Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney DiseaseRecruitingNCT06217302Phase 32 countries
- Improving Kidney Care in Type 2 Diabetes: A Study of Pharmacist Prescribing Versus Usual CareRecruitingNCT07169422Not applicable1 country
- The Non-high-density Lipoprotein Cholesterol (Non-HDL-C) to High-density Lipoprotein Cholesterol (HDL-C) Ratio (NHHR) and Its Association With Occurrence of Diabetic Nephropathy in Patients With Diabetes MellitusNot yet recruitingNCT07476248
- Research on Innovative Traditional Chinese Medicine Diagnosis and Treatment Technologies for Diabetic Nephropathy Driven by Multi-Omics and Artificial IntelligenceNot yet recruitingNCT07459946Not applicable
- Irisin Hormone as a Novel Diagnostic Marker for Detection and Progression of Diabetic Nephrophathy PatientsNot yet recruitingNCT07435480
- Transformative Research in Diabetic Nephropathy 2.0RecruitingNCT074442031 country
- Transformative Research in Diabetic NephropathyRecruitingNCT029869841 country
- Immune System in Diabetic Kidney DiseaseEnrolling by invitationNCT072924931 country
- Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cell Therapy in Diabetic Nephropathy Patients: A Clinical TrialRecruitingNCT07396155Phase 1/21 country
- Formoterol in DiabetesRecruitingNCT07022418Phase 21 country