Drug
Chlorthalidone clinical trials
Also written Thalitone and Chlortalidone.
- studies test it
- 45
- open now
- 6
- in phase 3
- 17
- first study started
- 2007
Keep track of what changes. Save the Chlorthalidone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Studies by the year they started
45 studies that test it; most in 2014 (8)
| Year | Studies |
|---|---|
| 2007 | 1 |
| 2009 | 4 |
| 2010 | 3 |
| 2011 | 2 |
| 2012 | 2 |
| 2013 | 4 |
| 2014 | 8 |
| 2015 | 1 |
| 2016 | 5 |
| 2019 | 3 |
| 2020 | 1 |
| 2022 | 3 |
| 2023 | 4 |
| 2024 | 2 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 4
- Phase 2
- 7
- Phase 3
- 17
- Phase 4
- 11
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 14 · Other 31
Takeda (7) · Hospital de Clinicas de Porto Alegre (3) · Indiana University (2) · Creighton University (2) · EMS (2) · University of Texas Southwestern Medical Center (1) · Hospital Israelita Albert Einstein (1) · Eurofarma Laboratorios S.A. (1)
Often tested with
Tested in the same studies.
Azilsartan medoxomil (7) · Amlodipine (6) · Hydrochlorothiazide (6) · Losartan (3) · Amiloride (3) · Spironolactone (2) · Telmisartan (2) · Eplerenone (2)
Studies
Open first, then newest update. How each study uses Chlorthalidone is read from its arms, and is right about nine times in ten.
Testing it · 45
- Cardiac Effects of Mineralocorticoid Receptor Antagonism After Hypertensive Disorders of PregnancyRecruitingPhase 2Massachusetts General HospitalNCT07238400Written as Chlorthalidone 25 mg daily
- CaOx Stone PreventionRecruitingPhase 4Icahn School of Medicine at Mount SinaiNCT07225764Written as Chlorthalidone
- Indapamide and Chlorthalidone to Reduce Urine Supersaturation for Kidney Stone PreventionRecruitingPhase 2Insel Gruppe AG, University Hospital BernNCT06111885Written as Chlorthalidone 25mg
- Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in HypertensionRecruitingPhase 4Brigham and Women's HospitalNCT05593055Written as Chlorthalidone
- Spironolactone in CKD Enabled by Chlorthalidone: PILOTRecruitingPhase 2Indiana Institute for Medical ResearchNCT05222191Written as Chlorthalidone
- Skin Sodium and Salt Sensitivity of Blood PressureNot yet recruitingNot applicableCambridge University Hospitals NHS Foundation TrustNCT05976438Written as Chlortalidone
- Diuretic Use in Hemodialysis Patients With Residual Renal FunctionTerminatedPhase 4University of AlbertaNCT05915286Written as Chlorthalidone
- Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.CompletedEarly Phase 1University of Texas Southwestern Medical CenterNCT06287580Written as chlorthalidone
- Hypertension in Young Adults TrialTerminatedPhase 2University of California, San FranciscoNCT05370599Written as Anti-hypertensive agent: Chlorthalidone
- Candesartan Cilexetil + Chlorthalidone + Amlodipine Versus Exforge HCT®️ for Systemic Arterial HypertensionCompletedPhase 3Hospital Israelita Albert EinsteinNCT05920005Written as candesartan cilexetil + chlorthalidone + amlodipine
- Safety and Efficacy of Chlorthalidone + Amiloride to Elderly Patients Treatment With Arterial HypertensionCompletedPhase 3Eurofarma Laboratorios S.A.NCT01191450Written as Chlorthalidone 25 mg + amiloride hydrochloride 5 mg
- Diuretic Comparison ProjectCompletedPhase 3VA Office of Research and DevelopmentNCT02185417Written as Chlorthalidone (CTD)
- Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)WithdrawnPhase 4Northwestern UniversityNCT05275907Written as Chlorthalidone
- Chlorthalidone in Chronic Kidney DiseaseCompletedPhase 2Indiana UniversityNCT02841280Written as Chlorthalidone
- Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine CalciumCompletedNot applicableVA New York Harbor Healthcare SystemNCT02711670Written as chlorthalidone
- Non-interaction Study of Chlorthalidone and Losartan in Fixed Combination, in Healthy Subjects, Under Fasting ConditionsCompletedPhase 1Laboratorios Silanes S.A. de C.V.NCT05090449Written as Chlorthalidone (HIGROTON® 50)
- Study of Exposure to Substances Prohibited by the World Anti-Doping Agency in Healthy Volunteers.CompletedPhase 1Parc de Salut MarNCT04757532Written as Chlorthalidone
- Safety and Efficacy of Chlorthalidone in Type 1 DiabetesTerminatedPhase 2University of RochesterNCT03325114Written as Chlorthalidone
- Mechanisms of Refractory Hypertension (Carvedilol)WithdrawnNot applicableUniversity of Alabama at BirminghamNCT02357004Written as Chlorthalidone
- Efficacy of Chlorthalidone and Hydrochlorothiazide Combined With Amiloride on Blood Pressure in Primary Hypertension.Status unknownPhase 3Hospital de Clinicas de Porto AlegreNCT03928145Written as Chlorthalidone 25 mg
See all 45 studies that test Chlorthalidone →
Given in every arm · 6 — Chlorthalidone is usual care beside what is tested
- Comparison of Optimal Hypertension RegimensCompletedPhase 4Cambridge University Hospitals NHS Foundation TrustNCT02847338Written as Chlortalidone
- Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrateCompletedNot applicableUniversity of Texas Southwestern Medical CenterNCT02665117Written as Chlorthalidone
- Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV DiseaseCompletedPhase 4Hanmi Pharmaceutical Company LimitedNCT03666351Written as Amlodipine/Losartan/Chlorthalidone
- Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD TrialCompletedPhase 2Hospital General de México Dr. Eduardo LiceagaNCT03923933Written as Chlorthalidone
- The Effect in Renal Function on Patients With Type 1 Cardiorenal Syndrome Treated With Two Strategies of Furosemide.CompletedPhase 2Hospital Civil de GuadalajaraNCT04393493Written as Chlortalidone
- Uric Acid and Hypertension in African AmericansCompletedPhase 3University of FloridaNCT00241839Written as Chlorthalidone
As the comparator · 4 — what is tested is compared with Chlorthalidone
- Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in ObesityCompletedPhase 4Brigham and Women's HospitalNCT04519164Written as Chlorthalidone with potassium chloride
- PK Study of YH22162 FDC Compared to Combination of Twynsta and HygrotonCompletedPhase 1Yuhan CorporationNCT02496910Written as Chlorthalidone 25mg
- Diuretics and Angiotensin-Receptor Blocker Agents in Patients With Stage I HypertensionCompletedPhase 3Hospital de Clinicas de Porto AlegreNCT00971165Written as Chlorthalidone plus amiloride
- Study to Evaluate the Efficacy and Safety of the Combination of Valturna and Amlodipine or Valturna and Chlorthalidone Versus Valturna Alone in Patients With Stage 2 Hypertension and DiabetesTerminatedPhase 4Novartis PharmaceuticalsNCT01368536Written as Chlorthalidone
Codes
What other systems call Chlorthalidone · ClinicalTrials.gg INT007207
- MeSH (NLM) D002752ChlorthalidoneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) Q0MQD1073QCHLORTHALIDONEConfirmed FDA, NLM, Wikidata
- RxNorm 2409Confirmed FDA, Wikidata
- Wikidata Q425289chlorthalidoneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47449ChlorthalidoneOne source FDA
- DrugBank DB00310One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D002752 | Chlorthalidone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | Q0MQD1073Q | CHLORTHALIDONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2409 | — | Confirmed FDA, Wikidata |
| Wikidata | Q425289 | chlorthalidone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47449 | Chlorthalidone | One source FDA |
| DrugBank | DB00310 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.