Pelvic Organ Prolapse clinical trials
The registry lists 521 studies for Pelvic Organ Prolapse across more than 10 countries. 80 are recruiting or about to start. 403 of them are mainly about Pelvic Organ Prolapse (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 3 narrower conditions too, such as Uterine Prolapse: 664 studies, 101 open.
ClinicalTrials.gov finds 690 studies for Pelvic Organ Prolapse. How that becomes 520 here
This page counts the studies the registry files under Pelvic Organ Prolapse, and those it files under no condition that list Pelvic Organ Prolapsethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 690Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −139Filed under a narrower condition, counted on its own pageUterine Prolapse 66 · Rectal Prolapse 46 · Cystocele 26
- −2List Pelvic Organ Prolapse as a condition, but the registry did not file them under itMost often written as “Pelvic Organ Prolapse Vaginal Surgery” (1) and “Voiding Dysfunction After Pelvic Organ Prolapse Surgery” (1). The registry filed them under other conditions only, most often Prolapse (1) and Patient Satisfaction (1).
- −29Match it another way24 name it in the title, 1 in a keyword, and 4 by a synonym or other text the search reads.
- 520The count on this page7 of them list Pelvic Organ Prolapse in their own words; the registry filed them under no condition.
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Status
Who runs them
TriHealth Inc. (15) · Peking Union Medical College Hospital (12) · Atlantic Health System (11) · National Taiwan University Hospital (10) · The Cleveland Clinic (9) · Centre Hospitalier Universitaire de Nīmes (8) · Gaziosmanpasa Research and Education Hospital (8) · University of North Carolina, Chapel Hill (6)
What is being tested here
Drugs under test in Pelvic Organ Prolapse studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Suzetrigine | 2 | 0 | 2 |
| Bupivacaine | 1 | 0 | 7 |
| Gabapentin | 0 | 1 | 3 |
| Conjugated estrogens | 0 | 1 | 3 |
| Dexamethasone | 0 | 1 | 3 |
| Nitrofurantoin | 0 | 0 | 2 |
| Estradiol | 0 | 0 | 2 |
| Tranexamic Acid | 0 | 1 | 2 |
| Cranberry | 0 | 0 | 1 |
| Estriol | 0 | 1 | 1 |
Drug classes tested here Local anesthetics 1 open · Estrogens 6 · Corticosteroids 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Sep 2027Vaginal Estrogen for Improvement of Outcomes Following Pelvic Organ Prolapse Surgery · Phase 3 · Sarah Wozney
- Nov 2026Composite Outcomes of Mesh vs Suture Techniques for Prolapse Repair: A Randomized Controlled Multicentre Trial · University of British Columbia
- Nov 2026Safety and Efficacy of Different Procedures of Colpocleisis: a Randomized Controlled Trial · Lan Zhu
- Nov 2026Patient Education in the Clinical Management of Pessary · Peking Union Medical College Hospital
- Nov 2026A Randomized Controlled Trail of Uterosacral Ligament Suspension in the Treatment of Pelvic Organ Prolapse · Lan Zhu
- Nov 2026A Randomized Controlled Trial of Modified Ischial Spinous Fascia Fixation and Sacrospinous Ligament Fixation in the Treatment of Pelvic Organ Prolapse · Lan Zhu
- Nov 2026Barriers and Enablers to Accessing Medical Care for Urinary Incontinence and Prolapse in GLobal Majority Women · Manchester University NHS Foundation Trust
- Nov 2026Pelvic Floor Rehabilitation of Female Pelvic Floor Dysfunction · Mingfu Wu
- Dec 2026Intraoperative Costs and Patient Perceptions in Sacrocolpopexy for Prolapse · Mayo Clinic
- Dec 2026LAparoscopic Preventive PRErectal Mesh · University Hospital, Lille
Who these studies take
Of the 53 Pelvic Organ Prolapse studies recruiting now, 31 (58%) set no upper age limit and 10 (19%) stop at 75 or younger. 2 (4%) take children under 18. 49 (92%) are for women only and 0 (0%) for men only; 14 (26%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (4%) | 0 (0%) |
| 18 | 36 (68%) | 4 (8%) |
| 30 | 44 (83%) | 4 (8%) |
| 40 | 47 (89%) | 4 (8%) |
| 50 | 49 (92%) | 4 (8%) |
| 65 | 50 (94%) | 4 (8%) |
| 75 | 48 (91%) | 4 (8%) |
| 85 | 37 (70%) | 4 (8%) |
Across all 521 studies, recruiting or not: 13% stop at 75 or younger and 6% at 65; 8% take children; 98% are for women only and <1% for men only; 24% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Pelvic Organ Prolapse studies take
Of 179 interventional studies with no phase under Pelvic Organ Prolapse, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 23 mo12–48 · 179 studies | — | 22 mo12–43 · 162 studies |
| Observational | 31 mo16–63 · 61 studies | — | 26 mo15–51 · 55 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
Stopped1
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 521. Browse all 521 → or search them.
- The Preventive Efficacy of ULP for Stress Urinary Incontinence After Pelvic Organ Prolapse SurgeryNot yet recruitingNCT07923968Not applicable1 country
- Safety and Performance of a Pelvic Floor Mesh Implant for Laparoscopic Sacrocolpopexy (ProGYNious)RecruitingNCT07497321Not applicable2 countries
- Pelvic Floor Muscle Training During PregnancyRecruitingNCT07104292Not applicable1 country
- Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled TrialNot yet recruitingNCT07862660Not applicable1 country
- Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain ManagementNot yet recruitingNCT07856654Phase 41 country
- Improving Uroflowmetry Interpretability: Evaluating the Impact of Patient Reminder SystemsRecruitingNCT07692789Not applicable1 country
- Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive SurgeryNot yet recruitingNCT07600697Phase 41 country
- Pelvic Floor Rehabilitation of Female Pelvic Floor DysfunctionRecruitingNCT064612341 country
- How Low Can You GoNot yet recruitingNCT07786337Not applicable
- Poly-L-Lactic Acid for Vulvovaginal Tissue RegenerationRecruitingNCT07544667Not applicable1 country
- Vaginal Estrogen for Improvement of Outcomes Following Pelvic Organ Prolapse SurgeryRecruitingNCT07030426Phase 31 country
- Centered Surgery - Preoperative Counseling and Patient SatisfactionRecruitingNCT074714641 country
- Safety and Performance of a Pelvic Floor Mesh Implant (LatGYNious)RecruitingNCT07066761Not applicable2 countries
- Ethicon Pelvic Mesh Post Market Clinical Follow-up RegistryRecruitingNCT048291757 countries
- The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.RecruitingNCT07414849Not applicable1 country
- Evaluation of a Personalizable Pessary for Pelvic Organ ProlapseRecruitingNCT06954701Not applicable1 country
- Vaginal Vault Native Tissue SuspensionRecruitingNCT07517965Not applicable1 country
- Urinary Continence After Vaginal Surgery for Genital Prolapse in the Spanish Population.Not yet recruitingNCT076280361 country
- The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early RehabilitationRecruitingNCT07430865Not applicable1 country
- LAparoscopic Preventive PRErectal MeshRecruitingNCT03766048Not applicable1 country
- Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction SurgeryRecruitingNCT076012821 country
- The Finnish Uterine Prolapse Surgery Trial (The Fin-UP Trial)RecruitingNCT07566949Not applicable1 country
- Accelerometer Measured Early Recovery After Prolapse SurgeryRecruitingNCT07218016Not applicable1 country
- Central Sensitization Inventory and Symptoms of Pelvic Floor DysfunctionsEnrolling by invitationNCT071545761 country
- Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairSRecruitingNCT05602246Not applicable2 countries
- Effect of Paracervical Block on Postoperative Pain After vNOTES Uterosacral Ligament SuspensionRecruitingNCT07440576Not applicable1 country
- Effects of Pelvic Floor Muscle Training With & Without Hypopressive ExercisesRecruitingNCT07440875Not applicable1 country
- Comparison of Outpatient Rehabilitation Versus Self-training for the Treatment and Prevention of Postpartum Pelvic Floor DysfunctionRecruitingNCT07426770Not applicable1 country
- Sequence of Midurethral Sling Placement During Robotic SacrocolpopexyRecruitingNCT07008898Not applicable1 country
- Are There Benefits of Using Energy-based Devices for Opportunistic Salpingo-oophorectomy During Vaginal Hysterectomy Compared to a Standard Cold Approach?RecruitingNCT07379411Not applicable1 country
- Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority StudyRecruitingNCT07359755Not applicable1 country
- Barriers and Enablers to Accessing Medical Care for Urinary Incontinence and Prolapse in GLobal Majority WomenNot yet recruitingNCT073101211 country
- Enabling Self-Care for Pessary Users in Rural SettingEnrolling by invitationNCT07084818Not applicable1 country
- Pragmatic Evaluation of Performance and Safety of the Anchorsure® Transvaginal Device for Surgical Treatment of Apical Prolapse in WomenRecruitingNCT058368441 country
- Transvaginal Mesh vs. Laparoscopic Colposacropexy- StudyRecruitingNCT04478747Not applicable1 country
- Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss TherapyNot yet recruitingNCT071758051 country
- POPQ Associated With Total Laparoscopic HysterectomyNot yet recruitingNCT071372991 country
- VNOTES Approach in Mesh Free Sacrocolpopexy: A Functional and Anatomic EvaluationRecruitingNCT07114029Not applicable1 country
- Comparison of V-NOTES and Laparoscopic Mesh-Free Sacrocolpopexy TechniquesRecruitingNCT07082023Not applicable1 country
- Post-Hysterectomy Vaginal Length: Horizontal vs. Vertical ClosureRecruitingNCT07067645Not applicable1 country
- Laparoscopic Pectopexy and Laparoscopic Colporrhaphies in Pelvic Organ Prolapse TreatmentEnrolling by invitationNCT069029091 country
- Impact of Equestrian Sports, CrossFit, and Gym Training on Pelvic Floor Health (PELFISPORT )Not yet recruitingNCT06848634
- An Institutional Audit of the Short Term Complications and Long Term Outcomes of Patients Undergoing Laparoscopic Sacrocolpopexy for Vault/cervical Prolapse.Enrolling by invitationNCT043784001 country
- Urinary Catheter Self-Discontinuation After Urogynecology SurgeryRecruitingNCT05860634Not applicable1 country
- Digital Care Programs for Female Pelvic HealthEnrolling by invitationNCT055134171 country
- Long-term Evaluation of the Efficacy and Safety of Splentis for the Treatment of Primary Apical Pelvic Organ ProlapseRecruitingNCT050424531 country
- Vaginal Prolapse Pessary Material Trial PVC vs SiliconNot yet recruitingNCT06641804Not applicable
- Fat Injection for Rectocele Treatment: A Novel ApproachNot yet recruitingNCT06604702Not applicable
- Quality of Life After Conservative and Surgical Treatment of Pelvic Organ ProlapseRecruitingNCT041108211 country
- The Influence of Using Vascularized Vaginal Flap on the Efficacy of Mesh-augmented Sacrospinous HysteropexyRecruitingNCT06494982Not applicable1 country