Uterine Prolapse clinical trials
The registry lists 111 studies for Uterine Prolapse across more than 10 countries. 18 are recruiting or about to start. 70 of them are mainly about Uterine Prolapse (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-30.
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Status
Who runs them
Atlantic Health System (6) · Fatih Sultan Mehmet Training and Research Hospital (3) · Zealand University Hospital (3) · Coloplast A/S (3) · The Cleveland Clinic (3) · Centre Hospitalier Universitaire de Nīmes (3) · Karolinska Institutet (2) · University of Texas Southwestern Medical Center (2)
What is being tested here
Drugs under test in Uterine Prolapse studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Conjugated estrogens | 0 | 0 | 1 |
| Lidocaine Topical | 0 | 0 | 1 |
| Dexamethasone | 0 | 0 | 1 |
| Ropivacaine | 0 | 0 | 1 |
| Liposomal Bupivacaine | 0 | 0 | 1 |
| Bupivacaine | 0 | 0 | 1 |
| Cefuroxime | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Jan 2027Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy · Aesculap AG
- Feb 2027Laparoscopic Pectopexy and Laparoscopic Colporrhaphies in Pelvic Organ Prolapse Treatment · Tampere University Hospital
- Jul 2027Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery · Meander Medical Center
- Jul 2027Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy · Fatih Sultan Mehmet Training and Research Hospital
- Oct 2027Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study · University of Sao Paulo General Hospital
Who these studies take
Of the 16 Uterine Prolapse studies recruiting now, 10 (63%) set no upper age limit and 5 (31%) stop at 75 or younger. 1 (6%) take children under 18. 15 (94%) are for women only and 0 (0%) for men only; 2 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (6%) | 0 (0%) |
| 18 | 10 (63%) | 1 (6%) |
| 30 | 12 (75%) | 1 (6%) |
| 40 | 14 (88%) | 1 (6%) |
| 50 | 15 (94%) | 1 (6%) |
| 65 | 15 (94%) | 1 (6%) |
| 75 | 13 (81%) | 1 (6%) |
| 85 | 11 (69%) | 1 (6%) |
Across all 111 studies, recruiting or not: 19% stop at 75 or younger and 10% at 65; 5% take children; 97% are for women only and 1% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Uterine Prolapse studies take
Of 37 interventional studies with no phase under Uterine Prolapse, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 18 mo13–68 · 37 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 111. Browse all 111 → or search them.
- Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES HysterectomyRecruitingNCT07730970Not applicable1 country
- Safety and Performance of a Pelvic Floor Mesh Implant (LatGYNious)RecruitingNCT07066761Not applicable2 countries
- The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.RecruitingNCT07414849Not applicable1 country
- Combined Effects of Pelvic Floor Retraining and Hypopressive Exercises in Uterine Prolapse OutcomesRecruitingNCT07642180Not applicable1 country
- Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total HysterectomyRecruitingNCT060241092 countries
- BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)RecruitingNCT06754046Not applicable1 country
- The Finnish Uterine Prolapse Surgery Trial (The Fin-UP Trial)RecruitingNCT07566949Not applicable1 country
- Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority StudyRecruitingNCT07359755Not applicable1 country
- Biological OviTex Versus Synthetic Graft in Robotic Prolapse SurgeryRecruitingNCT06430931Not applicable1 country
- The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.RecruitingNCT072957821 country
- Transperineal Ultrasound Evaluation of Vesicourethral Angle and de Novo SUI After Colpocleisis SurgeryRecruitingNCT07071818Not applicable1 country
- Post-Hysterectomy Vaginal Length: Horizontal vs. Vertical ClosureRecruitingNCT07067645Not applicable1 country
- Laparoscopic Pectopexy and Laparoscopic Colporrhaphies in Pelvic Organ Prolapse TreatmentEnrolling by invitationNCT069029091 country
- Prospective Observational Prolapse StudyRecruitingNCT047010471 country
- Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium LaserRecruitingNCT05335317Not applicable1 country
- The Impact of Long-term Pessary Use on Pelvic Organ Prolapse oìduring Covid-19 Pandemic in Patients Attending SurgeryNot yet recruitingNCT062344491 country
- Vaginal Native Tissues Repair for Pelvic Organ ProlapseRecruitingNCT03875989Not applicable1 country
- Transvaginal Sacrospinous Hysteropexy Versus Laparoscopic Uterine Lateral SuspensionRecruitingNCT055869841 country
- Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal ProlapseActive, not recruitingNCT05063331Not applicable1 country
- Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial DesignActive, not recruitingNCT02676973Not applicable1 country
- The Effects of Platelet Rich Plasma Adjuvant to Type I/III Collagen Ratio, Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Pelvic Organ Prolapse RepairCompletedNCT07150442Not applicable1 country
- Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)Active, not recruitingNCT07120945Not applicable1 country
- Cross-Shaped Vaginal Pessary for Pelvic Organ ProlapseCompletedNCT07554651Not applicable1 country
- Perineal Massage for Pessary ExaminationsActive, not recruitingNCT06416982Not applicable1 country
- Complications Associated With Promontofixation for Pelvic Organ Prolapse: Comparing Robot Assisted Laparoscopic and Non-robot Assisted Laparoscopic Surgical ProceduresCompletedNCT01320215Not applicable1 country
- Effectiveness of Laparoscopic Lateral Suspension With or Without Hysterectomy in Pelvic Organ ProlapseCompletedNCT070948151 country
- Quality of Life Assessment in Patients With Different Degrees of Pelvic Organ ProlapseCompletedNCT070802031 country
- Effects of Kegel Ball and Pelvic Floor Exercises on Sexual Function, Unrınary Incontinence and Quality of Life in WomenActive, not recruitingNCT07048145Not applicable1 country
- Impact of Defecation Posture on Ease of First Bowel Movement Following Posterior RepairCompletedNCT06253689Not applicable1 country
- Clinical Trial of "Magic Gyno" Laser DeviceCompletedNCT05463081Not applicable1 country
- Sacrocolpopexy With Posterior Repair Obstructed Defecation SymptomsCompletedNCT03658395Not applicable1 country
- Impact of Preop Video on Patient AnxietyActive, not recruitingNCT05633901Not applicable1 country
- A New POP (Pelvic Organ Prolapse) Scoring System: Validity and ReliabilityCompletedNCT065207221 country
- Pectopexy Autologous Vs MeshActive, not recruitingNCT06524700Not applicable2 countries
- Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic SacrocolpopexyCompletedNCT04440475Not applicable1 country
- Surgical Repair of Vaginal Wall Prolapse Using Gamma Irradiated Amniotic Membrane as a ScaffoldCompletedNCT05355623Not applicable1 country
- Investigation to Minimize Prolapse Recurrence of the Vagina Using EstrogenCompletedNCT02431897Phase 41 country
- Lessons on Urethral Lidocaine in UrodynamicsCompletedNCT04038099Phase 41 country
- What Affects Willingness to Self-manage a Pessary?Status unknownNCT057506151 country
- Efficacy Study of Vaginal Mesh for ProlapseCompletedNCT00475540Not applicable1 country
- Continuous Stitches Versus Simple Interrupted Stitches for Anterior ColporrhaphyStatus unknownNCT05449054Not applicable1 country
- Effect of Preoperative Fiber on Postoperative Bowel FunctionCompletedNCT04882995Not applicable1 country
- Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine ProlapseTerminatedNCT01594372Not applicable1 country
- Restorelle® Mesh Versus Native Tissue Repair for ProlapseCompletedNCT021626156 countries
- Assessment of Potential Biomarkers in Women With Symptoms of Overactive Bladder and Pelvic Organ ProlapseStatus unknownNCT035162921 country
- Combination of Laparoskopic Uterosacral Ligament and Round Ligament Plication, A Meshless Method in the Surgical Treatment of Pelvic Organ Prolapse.Status unknownNCT048940321 country
- Pudendal Block Using Liposomal Bupivacaine vs. Standard Treatment During Sacrospinous Ligament FixationStatus unknownNCT03664986Phase 41 country
- Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?CompletedNCT03338400Phase 21 country
- Sacrocolpopexy Versus Vaginal Mesh Procedure for Pelvic ProlapseStatus unknownNCT01097200Not applicable1 country
- 4K Versus 3D Laparoscopic Colporraphy by Surgeons in Training: a Prospective Randomized TrialStatus unknownNCT046370221 country