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RecruitingNCT07104292Updated Nov 28, 2025

Pelvic Floor Muscle Training During Pregnancy

An interventional study of PFMT and Standard care in Pelvic Floor, Urinary Incontinence and Anal Incontinence, sponsored by University of Southern Denmark. Recruiting at 1 site in Denmark. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-11-28.

Sponsored by University of Southern Denmark · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
734
Allocation
Randomized
Ages
18 Years and older
Sex
Female
01

Study summary

The project seeks to investigate effectiveness of PFMT during pregnancy.

Read the detailed description

First-time pregnant women will be recruited through visitations received from family doctors in all obstetrics departments of the Southern Denmark Region. Women will be randomised into two groups: ( Pelvic Floor Muscle Training) PFMT and a control group (standard care). The motivation-informed intervention will tackle both exercise engagement and exercise adherence. The women will receive an easily accessible, home-based PFMT program electronically in which they will be motivated to start and engage during pregnancy with continuity after birth. The data regarding pelvic floor disorders will be obtained at baseline, follow-ups once every trimester of pregnancy, as well as six weeks, three months, and six months postpartum with further follow-up after the study. The data regarding obstetric outcomes will be collected from electronic patient records. For evaluation of implementation process, data regarding motivation and training acceptability will be obtained via questionnaire at the baseline and at follow-up together with telephonically interviews during pregnancy and postpartum.

02

Conditions studied

  • Pelvic Floor
  • Urinary Incontinence
  • Anal Incontinence
  • Pelvic Organ Prolapse
  • Sexual Dysfunction
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Woman in the 1st trimester of pregnancy (up to 12+6 weeks of gestation)
  • Para 0 (no previous birth or pregnancy > 16 weeks of gestation)
  • Understands, writes, and reads fluently in Danish or English
  • Has a smart phone or computer/tablet to reach the training program

Exclusion criteria

Exclusion Criteria:

  • Severe psychiatric illness (e.g. schizophrenia, bipolar disorder, severe depression or anxiety)
  • Active substance abuse
  • Acute social crises (e.g. homelessness, ongoing domestic violence, severe financial instability, lack of social support)
  • Women with limited capacity to provide informed consent (due to cognitive impairment or language barriers)
  • Previous pregnancy of > 16 weeks of gestation
04

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
734 participants (estimated)

Study arms

  • Experimental
    Pelvic Floor Muscle Training (PFMT)

    A Danish professional pelvic floor physiotherapist together with a midwife and an urogynecologist have created a free of charge training program, which is easily accessible via a danish website "www.kvindekrop.dk" or via the app "Pelvic FloorTrainer". The women will receive an easily accessible, home-based PFMT program electronically in which they will be motivated to start and engage during pregnancy with continuity after birth.

    Behavioral: PFMT

  • Placebo comparator
    Standard care

    The control group will receive routine care - recommendation to do the training without any further instructions.

    Behavioral: Standard care

Interventions

  • BehavioralPFMT

    The motivation-informed intervention will tackle both exercise engagement and exercise adherence. Participating women will be introduced to the app and its videos following training. The participants will be introduced not only to muscle training, but also to muscle relaxation. The training will be recommended three to four times a week during pregnancy with further continuity after giving birth.

  • BehavioralStandard care

    Standard care

05

What researchers measure

Primary outcomes

  1. Urinary incontinence (UI) incidence at 3 months postpartum

    International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) score between 0 (perfect continence) and 21 (total incontinence).

    Time frame: At 3 months follow-up after giving birth

Secondary outcomes

  1. Urinary incontinence at the 1st trimester of pregnancy

    ICIQ-UI SF score between 0-21

    Time frame: At baseline, during the 1st trimester of pregnancy (gestational age (GA) up to 12 weeks +6 days)

  2. Urinary incontinence at the 2nd trimester of pregnancy

    ICIQ-UI SF score between 0-21

    Time frame: At the follow-up at Gestational age 26 weeks and 0 days

  3. Urinary incontinence incidence at the 3rd trimester of pregnancy

    ICIQ-UI SF score between 0-21

    Time frame: At the follow-up at Gestational Age 36 weeks and 0 days

  4. Urinary incontinence incidence at 6 weeks postpartum

    ICIQ-UI SF score between 0-21

    Time frame: At the follow-up at 6 weeks postpartum

  5. Anal incontinence (AI) incidence at inclusion, during the 1st trimester of pregnancy

    Colorectal-anal distress inventory 8 (CRAD-8), a part of Pelvic Floor Disability Index (PFDI-20) questionnaire: score calculated by the mean value of all item scores (possible 0-4) multiplied by 25 to obtain the score (range 0 to 100). Answer yes to one of the three questions about anal incontinence will be considered as AI.

    Time frame: At baseline, during the 1st trimester of pregnancy (gestational age (GA) up to 12 weeks +6 days)

  6. Anal incontinence (AI) in the 2nd trimester of pregnancy

    Colorectal-anal distress inventory 8 (CRAD-8), score 0-100. Answer yes to one of the three questions about anal incontinence will be considered as AI.

    Time frame: At the follow-up at Gestational Age 26 weeks and 0 days

  7. Anal incontinence (AI) incidence in the 3rd trimester of pregnancy

    Colorectal-anal distress inventory 8 (CRAD-8), score 0-100. Answer yes to one of the three questions about anal incontinence will be considered as AI.

    Time frame: At the follow-up at Gestational Age 36 weeks and 0 days

  8. Anal incontinence (AI) incidence at 6 weeks postpartum

    Colorectal-anal distress inventory 8 (CRAD-8), score 0-100. Answer yes to one of the three questions about anal incontinence will be considered as AI.

    Time frame: At the follow-up at 6 weeks postpartum

  9. Anal incontinence (AI) incidence at 3 months postpartum

    Colorectal-anal distress inventory 8 (CRAD-8), score 0-100. Answer yes to one of the three questions about anal incontinence will be considered as AI.

    Time frame: At the follow-up at 3 months postpartum

  10. Anal incontinence (AI) incidence at 6 months postpartum

    Colorectal-anal distress inventory 8 (CRAD-8), score 0-100. Answer yes to one of the three questions about anal incontinence will be considered as AI.

    Time frame: At the follow-up at 6 months postpartum

  11. Sexual dysfunction incidence at inclusion, during the 1st trimester of pregnancy

    Female Sexual Function Index-6 (FSFI-6) score between 2 to 30

    Time frame: At baseline, during the 1st trimester of pregnancy (gestational age (GA) up to 12 weeks +6 days)

  12. Sexual dysfunction incidence at inclusion, during the 2nd trimester of pregnancy

    Female Sexual Function Index-6 (FSFI-6) score between 2 to 30

    Time frame: At the follow-up at Gestational Age 26weeks and 0 days

  13. Sexual dysfunction incidence at inclusion, during the 3rd trimester of pregnancy

    Female Sexual Function Index-6 (FSFI-6) score between 2 to 30

    Time frame: At the follow-up at Gestational Age 36 weeks and 0 days

  14. Sexual dysfunction incidence at 6 weeks postpartum

    Female Sexual Function Index-6 (FSFI-6) score between 2 to 30

    Time frame: At the follow-up at 6 weeks postpartum

  15. Sexual dysfunction incidence at 3 month postpartum

    Female Sexual Function Index-6 (FSFI-6) score between 2 to 30

    Time frame: At the follow-up at 3 month postpartum

  16. Sexual dysfunction incidence at 6month postpartum

    Female Sexual Function Index-6 (FSFI-6) score between 2 to 30

    Time frame: At the follow-up at 6 month postpartum

  17. Pelvic organ prolapse (POP) incidence at inclusion, during the 1st trimester of pregnancy

    Pelvic Organ Prolapse Distress Inventory 6 (POPDI-6), a part of Pelvic Floor Disability Index (PFDI-20) questionnaire: score calculated by the mean value of all item scores (possible 0-4) multiplied by 25 to obtain the score (range 0 to 100).

    Time frame: At baseline, during the 1st trimester of pregnancy (gestational age (GA) up to 12 weeks and 6 days)

  18. Pelvic organ prolapse (POP) incidence, in the 2nd trimester of pregnancy

    Pelvic Organ Prolapse Distress Inventory 6 (POPDI-6), a part of Pelvic Floor Disability Index (PFDI-20) questionnaire: score calculated by the mean value of all item scores (possible 0-4) multiplied by 25 to obtain the score (range 0 to 100).

    Time frame: At the follow-up at gestational age 26 weeks and 0 days

  19. Pelvic organ prolapse (POP) incidence, in the 3rd trimester of pregnancy

    Pelvic Organ Prolapse Distress Inventory 6 (POPDI-6), a part of Pelvic Floor Disability Index (PFDI-20) questionnaire: score calculated by the mean value of all item scores (possible 0-4) multiplied by 25 to obtain the score (range 0 to 100).

    Time frame: At the follow-up at gestational age 36 weeks and 0 days

  20. Pelvic organ prolapse (POP) incidence at 6 weeks postpartum

    Pelvic Organ Prolapse Distress Inventory 6 (POPDI-6), a part of Pelvic Floor Disability Index (PFDI-20) questionnaire: score calculated by the mean value of all item scores (possible 0-4) multiplied by 25 to obtain the score (range 0 to 100).

    Time frame: At the follow-up at 6 weeks postpartum

  21. Pelvic organ prolapse (POP) incidence at 3 months postpartum

    Pelvic Organ Prolapse Distress Inventory 6 (POPDI-6), a part of Pelvic Floor Disability Index (PFDI-20) questionnaire: score calculated by the mean value of all item scores (possible 0-4) multiplied by 25 to obtain the score (range 0 to 100).

    Time frame: At the follow-up at 3 months postpartum

  22. Pelvic organ prolapse (POP) incidence at 6 months postpartum

    Pelvic Organ Prolapse Distress Inventory 6 (POPDI-6), a part of Pelvic Floor Disability Index (PFDI-20) questionnaire: score calculated by the mean value of all item scores (possible 0-4) multiplied by 25 to obtain the score (range 0 to 100).

    Time frame: At the follow-up at 6 months postpartum

  23. Length of the second stage of delivery

    Length in minutes (minimum 0 - maximum 300 minutes).

    Time frame: The outcome is registered in electronic patient journal during delivery, but the outcome will be collected during the first 3 months postpartum.

  24. Delivery mode

    Vaginal, planned or unplanned Caesarean.

    Time frame: The outcome is registered in electronic patient journal during delivery, but the outcome will be collected during the first 3 months postpartum.

  25. Foetal position

    Cephalic regular (occiput anterior), cephalic occiput posterior or breech

    Time frame: The outcome is registered in electronic patient journal during delivery, but the outcome will be collected during the first 3 months postpartum.

  26. Episiotomy

    Yes or no

    Time frame: The outcome is registered in electronic patient journal during delivery, but the outcome will be collected during the first 3 months postpartum

  27. Perineal tear

    Yes or no; if yes - tear degree (1st, 2nd, 3rd (3a, 3b, 3c), 4th)

    Time frame: The outcome is registered in electronic patient journal during delivery, but the outcome will be collected during the first 3 months postpartum.

  28. Instrumental delivery

    Yes or no; if yes - type (vacuum assisted or forceps)

    Time frame: The outcome is registered in electronic patient journal during delivery, but the outcome will be collected during the first 3 months postpartum.

  29. Length of the first stage of delivery

    Length in minutes (minimum 0 - no maximum)

    Time frame: The outcome is registered in electronic patient journal during delivery, but the outcome will be collected during the first 3 months postpartum.

  30. Fidelity of PFMT

    Self-reported training frequency (from 0 to 4 times a week)

    Time frame: The questionnaire is filled every week from baseline to 6 months postpartum

  31. Other implementation outcomes: acceptability, feasibility, appropriateness

    Will be collected through short interviews

    Time frame: At study completion

06

Study locations

1 of 1 sites recruiting
  • Sygehus Sønderjylland
    Aabenraa, Southern Denmark 6200, Denmark
    Recruiting
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07104292
Lead sponsor
University of Southern Denmark
Responsible party
Sponsor
First posted
Aug 5, 2025
Start date
Oct 27, 2025
Primary completion
Aug 1, 2027 (estimated)
Completion
Aug 1, 2028 (estimated)
Last update
Nov 28, 2025

Study contacts

Greta Puriene
Contact
greta.puriene@rsyd.dk
+4571638335
Christina Prinds
Contact
cprinds@health.sdu.dk
+4565504953
Jan Stener Jørgensen
study chair · Esbjerg Hospital - University Hospital of Southern Denmark

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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