ClinicalTrials.gg
Not yet recruitingNCT07928609Updated Nov 10, 2026

Training in Adults With Parkinson's Disease

An interventional study of Exercise in PARKINSON DISEASE (Disorder), sponsored by Universidade do Estado do Pará. Not yet recruiting. Open to participants aged 60 Years and older. Per ClinicalTrials.gov, last updated 2026-11-10.

Sponsored by Universidade do Estado do Pará · Not applicable, Interventional, and Supportive care

Updated Nov 10, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
60 Years and older
Sex
All
01

Study summary

Patients with Parkinson's disease experience progressive deconditioning of the respiratory muscles, leading to weakness and potential ventilatory impairments. Evidence indicates that physical exercise positively affects these muscles in people with various clinical conditions. This study will evaluate the effects of multicomponent and resistance training on respiratory parameters and physical and functional capacities in individuals with Parkinson's disease. A total of 40 patients will be randomly allocated to two groups: 20 individuals in the multicomponent training group and 20 in the resistance training group. Both groups will undergo a three-month intervention with two sessions per week. All participants must continue standard pharmacological treatment for Parkinson's disease. Respiratory parameters will be assessed using respiratory pressure measurement and spirometry. Physical and functional capacities will be assessed using the Rikli and Jones test battery.

02

Conditions studied

  • PARKINSON DISEASE (Disorder)

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Keywords

  • Multicomponent Training
  • Resistance Training
  • Parkinson's Disease
  • Respiratory Parameters
03

In context

Parkinson Disease

4,573 studies on the registry are indexed under Parkinson Disease; 1,086 are open to participants now.

This study's planned enrollment of 20 is below the median of 40 across 3,353 interventional studies indexed under Parkinson Disease.

Browse Parkinson Disease studies →

Lead sponsor

Universidade do Estado do Pará is the lead sponsor of 8 studies on the registry; 5 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
60 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Hoehn and Yahr stages 1-3
  • Physical and mental requirements,
  • No history of exercise training in the preceding three months.
  • Standard pharmacological treatment for PD throughout the 12-week study period.

Exclusion criteria

Exclusion Criteria:

  • score \<24
  • Unstable cardiovascular disease or any other uncontrolled chronic condition
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

MMSE and MoCA

Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.

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Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
20 participants (estimated)

Study arms

  • Experimental
    Aerobic training

    The first group will undergo multicomponent training for three months, with two sessions per week

    Other: Exercise

  • Active comparator
    Resistance training

    The second group will undergo resistance training for the same period

    Other: Exercise

Interventions

  • OtherExercise

    Resistence training

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What researchers measure

Primary outcomes

  1. Inspiratory pressure

    Respiratory muscle strength will be assessed using a manovacuometer with a range of -300 to +300 cmH2O. Respiratory muscle strength during inspiration will be assessed.

    Time frame: three weeks

  2. Forced Vital Capacity

    Forced vital capacity, expressed in liters, will be assessed based on the maximum volume of inspired air, which will be measured in liters using a spirometer

    Time frame: three weeks

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Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • McMahon L, Blake C, Lennon O. A systematic review and meta-analysis of respiratory dysfunction in Parkinson's disease. Eur J Neurol. 2023 May;30(5):1481-1504. doi: 10.1111/ene.15743. Epub 2023 Mar 7. PubMed 36779856 ↗
  • Goetz CG, Tilley BC, Shaftman SR, Stebbins GT, Fahn S, Martinez-Martin P, Poewe W, Sampaio C, Stern MB, Dodel R, Dubois B, Holloway R, Jankovic J, Kulisevsky J, Lang AE, Lees A, Leurgans S, LeWitt PA, Nyenhuis D, Olanow CW, Rascol O, Schrag A, Teresi JA, van Hilten JJ, LaPelle N; Movement Disorder Society UPDRS Revision Task Force. Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results. Mov Disord. 2008 Nov 15;23(15):2129-70. doi: 10.1002/mds.22340. PubMed 19025984 ↗
  • Bouaziz W, Lang PO, Schmitt E, Kaltenbach G, Geny B, Vogel T. Health benefits of multicomponent training programmes in seniors: a systematic review. Int J Clin Pract. 2016 Jul;70(7):520-36. doi: 10.1111/ijcp.12822. Epub 2016 Jun 13. PubMed 27291143 ↗

Individual participant data

Plan to share: No

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Nov 10, 2026
Show all 1 update
  1. Nov 10, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07928609
Lead sponsor
Universidade do Estado do Pará
Responsible party
Rodrigo Santiago Barbosa Rocha (Director, Universidade do Estado do Pará) — Principal investigator
First posted
Nov 10, 2026
Start date
Nov 15, 2026 (estimated)
Primary completion
Dec 20, 2027 (estimated)
Completion
Jan 15, 2028 (estimated)
Last update
Nov 10, 2026

Study contacts

Amanda de Jesus L Researcher
Contact
prof_amandalopes@outlook.com
+55 91 985075007

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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