An interventional study of Cognitive-motor training and Conventional physiotherapy in Parkinson Disease, sponsored by National Yang Ming Chiao Tung University. Not yet recruiting at 1 site in Taiwan. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-10-30.
Sponsored by National Yang Ming Chiao Tung University · Not applicable, Interventional, and Treatment
Cognitive-motor training combines thinking tasks with physical movements, encouraging participants to choose appropriate actions and adjust their movements according to different task demands. Training that involves stopping or changing a movement may help people with Parkinson's disease respond to changing situations. These abilities may also support walking in challenging environments, such as stepping over obstacles. However, the effects of this type of training on cognitive function, walking performance, and brain activity remain unclear. Therefore, this study aims to compare the effects of cognitive-motor co-dependent training with conventional exercise training on these outcomes in people with Parkinson's disease.
4,573 studies on the registry are indexed under Parkinson Disease; 1,086 are open to participants now.
This study's planned enrollment of 50 is above the median of 40 across 3,353 interventional studies indexed under Parkinson Disease.
Browse Parkinson Disease studies →National Yang Ming Chiao Tung University is the lead sponsor of 208 studies on the registry; 60 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants receive 16 sessions of cognitive-motor training.
Other: Cognitive-motor training
Participants receive 16 sessions of conventional physiotherapy.
Other: Conventional physiotherapy
Cognitive-motor training is that cognitive tasks incorporated into motor tasks.
Conventional physiotherapy includes ROM exercise, stretching, strengthening exercise, and eye-hand coordination.
Gait speed
Gait speed during obstacle crossing was measured using the GAITRite system. Continuous obstacle-crossing walking performance was assessed using the GaitUp system.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Step length
Using GAITRite system to measure step length
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Step width
Using GAITRite system to measure step width
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Single support time
Using GAITRite system to measure single support time
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Gait Variability
Gait variability during continuous obstacle crossing will be assessed using the GaitUp system and expressed as the coefficient of variation (CV = standard deviation / mean × 100%) of step time and stride length.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Stride length
Using the GaitUp system to measure stride length during continuous obstacle-crossing walking.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Swing phase
Using the GaitUp system to measure swing phase during continuous obstacle-crossing walking.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Four Square Step Test
The Four Square Step Test is a test used to assess the ability to step over objects and measures the time in seconds to navigate all four squares.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Event-related potential - N2
Measure event-related potential through electroencephalography during the Go/No-go test
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Event-related potential - P300
Measure event-related potential through electroencephalography during the Go/No-go test
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Stroop color and word test
Record numbers of corrected color words which the subject responds within 45 sec.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Trail making test
Trail making test contain part A and part B. Faster completing the test indicates better executive function.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Part III of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS)
Motor symptoms will be assessed using Part III of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS). Scores range from 0 to 132, with higher scores indicating greater motor impairment.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Single-Leg Standing Balance
Balance will be assessed by measuring the time, in seconds, that participants can stand on one leg. Longer standing times indicate better balance.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
Montreal Cognitive Assessment
Montreal Cognitive Assessment ranges from 0 to 30. Higher scores reflect better cognitive performances.
Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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