An interventional study of RehaBEElitation serious game and Home exercise booklet in Parkinson Disease, sponsored by Federal University of Uberlandia. Completed at 1 site in Brazil. Open to participants aged 40 Years to 100 Years. Per ClinicalTrials.gov, last updated 2026-11-10.
Sponsored by Federal University of Uberlandia · Not applicable, Interventional, and Treatment
This is a non-randomized controlled trial with two parallel groups, with the general objective of developing and applying an assessment and intervention protocol based on a serious game for the rehabilitation of hand function in individuals with Parkinson's disease (PD). The experimental group trained with the RehaBEElitation serious game, controlled by hand and wrist movements through a wearable sensor glove; the control group trained the same five movements with a home exercise booklet. Both groups trained twice a week for six weeks (12 sessions of 30 to 45 minutes) and kept their usual physiotherapy. Participants were allocated in sequence: those enrolled first received the serious game and those enrolled later received the booklet. Manual dexterity, motor signs, quality of life, functioning and upper-limb muscle activation (surface electromyography) were assessed before and after the intervention. This trial was registered retrospectively.
4,573 studies on the registry are indexed under Parkinson Disease; 1,086 are open to participants now.
This study's enrollment of 27 is below the median of 40 across 3,353 interventional studies indexed under Parkinson Disease.
Browse Parkinson Disease studies →Federal University of Uberlandia is the lead sponsor of 61 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Group of subjects with Parkinson's disease trained with the RehaBEElitation serious game, twice a week for six weeks (12 sessions of 30 to 45 minutes), in addition to usual physiotherapy.
Device: RehaBEElitation serious game
Group of subjects with Parkinson's disease trained with a home exercise booklet with the same five movements, twice a week for six weeks (12 sessions of 30 to 45 minutes), with remote follow-up, in addition to usual physiotherapy.
Behavioral: Home exercise booklet
3D serious game controlled by hand and wrist movements (open/close the hand, pinch grip, wrist flexion-extension and radial-ulnar deviation, forearm pronation-supination) through a wearable glove with inertial and force sensors and haptic feedback. Twice a week for six weeks (12 sessions of 30 to 45 minutes).
Printed booklet with the same five hand and wrist movements, performed in two sets of 2 minutes with 1 minute of rest, twice a week for six weeks (12 sessions of 30 to 45 minutes), with remote follow-up.
Box and Block Test
Number of blocks transferred in 60 seconds with the most affected hand. Higher scores mean a better outcome.
Time frame: Baseline and 6 weeks
Nine-Hole Peg Test
Time in seconds to place and remove nine pegs. Higher values mean a worse outcome.
Time frame: Baseline and 6 weeks
MDS-Unified Parkinson's Disease Rating Scale Part III (MDS-UPDRS III)
Clinical scale of motor signs. Each item is rated from 0 (normal) to 4 (severe); higher scores mean a worse outcome.
Time frame: Baseline and 6 weeks
Parkinson's Disease Questionnaire (PDQ-39)
Disease-specific quality of life. Summary index from 0 to 100; higher scores mean a worse outcome.
Time frame: Baseline and 6 weeks
International Classification of Functioning, Disability and Health (ICF) checklist
Activity and participation components; functioning and disability in daily life.
Time frame: Baseline and 6 weeks
Muscle activation of the flexor carpi radialis (surface electromyography)
EMG of the flexor carpi radialis, normalised to the maximal voluntary contraction (%MVC), averaged across the reaching task, the Box and Block Test, the Nine-Hole Peg Test and the Trail Making Test.
Time frame: Baseline and 6 weeks
Muscle activation of the extensor carpi ulnaris (surface electromyography)
EMG of the extensor carpi ulnaris, normalised to the maximal voluntary contraction (%MVC), averaged across the reaching task, the Box and Block Test, the Nine-Hole Peg Test and the Trail Making Test.
Time frame: Baseline and 6 weeks
Muscle activation of the biceps brachii (surface electromyography)
EMG of the biceps brachii, normalised to the maximal voluntary contraction (%MVC), averaged across the reaching task, the Box and Block Test, the Nine-Hole Peg Test and the Trail Making Test.
Time frame: Baseline and 6 weeks
Muscle activation of the triceps brachii (surface electromyography)
EMG of the triceps brachii, normalised to the maximal voluntary contraction (%MVC), averaged across the reaching task, the Box and Block Test, the Nine-Hole Peg Test and the Trail Making Test.
Time frame: Baseline and 6 weeks
Muscle activation of the anterior deltoid (surface electromyography)
EMG of the anterior deltoid, normalised to the maximal voluntary contraction (%MVC), averaged across the reaching task, the Box and Block Test, the Nine-Hole Peg Test and the Trail Making Test.
Time frame: Baseline and 6 weeks
Trail Making Test part A
Time in seconds to complete part A. Higher values mean a worse outcome.
Time frame: Baseline and 6 weeks
Trail Making Test part B
Time in seconds to complete part B. Higher values mean a worse outcome.
Time frame: Baseline and 6 weeks
Handwriting movement analysis
Spiral and sinusoid drawings (10 copies of each).
Time frame: Baseline and 6 weeks
Plan to share: Yes — The data will be anonymised and stored in a safe and international platform (Zenodo - https://zenodo.org/communities/niats). Only data that cannot be used to identify the participants will be shared.
Supporting information: Study protocol, Statistical analysis plan, Analytic code
Time frame: Starting 6 months after publication
Access criteria: Researchers that wish to have access to the data can request access at https://zenodo.org/communities/niats. Access will be granted for research purposes under a data sharing agreement.
Data sharing details ↗ · zenodo.org
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Federal University of Uberlandia