Panic Disorder clinical trials
The registry lists 270 studies for Panic Disorder across more than 10 countries. 37 are recruiting or about to start. 132 of them are mainly about Panic Disorder (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
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· Enrollment: 300 → 450 participants
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Status
Who runs them
National Institute of Mental Health (NIMH) (9) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (7) · Karolinska Institutet (6) · Massachusetts General Hospital (6) · VA Office of Research and Development (5) · Universidade Federal do Rio de Janeiro (5) · Boston University Charles River Campus (4) · Laureate Institute for Brain Research, Inc. (4)
What is being tested here
Drugs under test in Panic Disorder studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Hydroxyzine | 1 | 0 | 1 |
| Paroxetine | 0 | 1 | 9 |
| Alprazolam | 0 | 0 | 7 |
| Cycloserine | 0 | 1 | 5 |
| Sertraline | 0 | 0 | 4 |
| Escitalopram | 0 | 0 | 4 |
| Quetiapine | 0 | 0 | 3 |
| Risperidone | 0 | 0 | 3 |
| Venlafaxine | 0 | 3 | 3 |
| Caffeine | 0 | 0 | 2 |
Drug classes tested here SSRIs 17 · Antipsychotics 8 · Anxiolytics 8 · SNRIs 4 · Stimulants 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Brief-intensive CBT Versus Once-weekly CBT in Anxiety-related Disorders · Amsterdam UMC, location VUmc
- Nov 2026Testing a Precision Psychotherapy System for Low-income Patients · National Council of Scientific and Technical Research, Argentina
- Dec 2026CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy · Jasper A. Smits
- Dec 2026Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method · Georgetown University
- Dec 2026Efficacy of Hydroxyzine for Patients With Panic Disorder · Sultan Qaboos University
- Jan 2027Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals · Massachusetts General Hospital
- Mar 2027A Clinical Trial to Evaluate the Efficacy and Safety of Meltz, a Digital Therapeutic Device, for Improving Panic Symptoms in Patients With Panic Disorder · AIMNEXT
- Mar 2027Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders · Lund University
- Mar 2027Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity · University of Minnesota
- Mar 2027A Novel Blood Test as a Biomarker in Mental Health · Fraser Health
Who these studies take
Of the 24 Panic Disorder studies recruiting now, 8 (33%) set no upper age limit and 15 (63%) stop at 75 or younger. 6 (25%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (21%) | 5 (21%) |
| 18 | 18 (75%) | 18 (75%) |
| 30 | 18 (75%) | 18 (75%) |
| 40 | 18 (75%) | 18 (75%) |
| 50 | 18 (75%) | 18 (75%) |
| 65 | 17 (71%) | 17 (71%) |
| 75 | 10 (42%) | 10 (42%) |
| 85 | 8 (33%) | 8 (33%) |
Across all 270 studies, recruiting or not: 70% stop at 75 or younger and 62% at 65; 16% take children; 1% are for women only and 0% for men only; 22% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Panic Disorder studies take
Of 87 interventional studies with no phase under Panic Disorder, half reached primary completion within 38 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 38 mo21–63 · 87 studies | — | 38 mo21–63 · 87 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered3
- Effectiveness of Internet-based Unified Protocol (iUP) for Emotional Problems: A Randomized Controlled TrialNov 2, 2026NCT07908628
- A Clinical Trial to Evaluate the Efficacy and Safety of Meltz, a Digital Therapeutic Device, for Improving Panic Symptoms in Patients With Panic DisorderOct 23, 2026NCT07892885
- Feasibility and Preliminary Outcomes of Compassion-Focused Group Therapy for Depression and AnxietyOct 15, 2026NCT07876453
Studies
Recruiting first, then most recently updated. Showing 50 of 270. Browse all 270 → or search them.
- Effectiveness of Internet-based Unified Protocol (iUP) for Emotional Problems: A Randomized Controlled TrialNot yet recruitingNCT07908628Not applicable1 country
- A Clinical Trial to Evaluate the Efficacy and Safety of Meltz, a Digital Therapeutic Device, for Improving Panic Symptoms in Patients With Panic DisorderNot yet recruitingNCT07892885Not applicable
- Qigong and Multicomponent Exercise in Panic DisorderRecruitingNCT07439224Not applicable1 country
- Anxiety Skills StudyRecruitingNCT07774481Not applicable1 country
- Efficacy of Expectancy Focused Exposure Therapy for Anxiety DisordersRecruitingNCT07753330Not applicable1 country
- Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.RecruitingNCT06934525Not applicable1 country
- Mindful Self-Compassion for Anxiety Disorders and DepressionRecruitingNCT05671419Not applicable1 country
- Non-Coding RNAs Gene Expression in Psychiatric DisordersNot yet recruitingNCT076499931 country
- CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based TherapyRecruitingNCT05467683Not applicable1 country
- Serotonin Variants & Gut Microbiota in Mental HealthNot yet recruitingNCT07634458
- Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4RecruitingNCT06563310Not applicable1 country
- A Transdiagnostic, Self-guided Internet Intervention ("Velibra") for Waitlist Patients With Anxiety DisordersRecruitingNCT04793828Not applicable1 country
- Mindful Self-compassion for Anxiety and Depression: Impact of Delivery MethodRecruitingNCT07028216Not applicable1 country
- LHC-CIDI-5 in Hong KongRecruitingNCT068045251 country
- A Novel Blood Test as a Biomarker in Mental HealthRecruitingNCT068561611 country
- Stepped Care Treatment for Anxiety ResilienceRecruitingNCT07228143Not applicable1 country
- Stepped Versus Stratified Care for Anxiety Disorders in YouthRecruitingNCT06942429Not applicable1 country
- Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety DisordersRecruitingNCT06661460Not applicable1 country
- Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for ComorbidityRecruitingNCT05117255Not applicable1 country
- Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track SubgroupsRecruitingNCT072120751 country
- Respiratory Training in the Treatment of Transdiagnostic Pathological AnxietyRecruitingNCT05427708Not applicable1 country
- Preoperative Pregabalin vs Gabapentin in Elderly Undergoing Surgry,Controlled TrialNot yet recruitingNCT07000201Not applicable1 country
- Analyzing the Benefits of Using SYMPTOMS-JIT for in Vivo Exposure in Anxiety DisordersRecruitingNCT06788119Not applicable1 country
- Metacognitive Therapy vs Unified Protocol for Patients With Comorbid Anxiety DisordersNot yet recruitingNCT06971692Not applicable1 country
- Investigations of Factors Associated With Treatment Response and Prognosis in Anxiety DisordersNot yet recruitingNCT067735851 country
- Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter TrialRecruitingNCT04900064Not applicable1 country
- Investigating the Impacts of Early Life Experience on the Brain & BehaviourRecruitingNCT068234921 country
- Multiple-Family Group Intervention Programming to Improve Mental Health of Adolescents Living With HIV in Ghana: An Implementation Science ApproachNot yet recruitingNCT06701942Not applicable
- Anxiety is One of the Most Frequent Disorders During the Perinatal Stage Which is Associated with Adverse Health Effects for Women and Their Babies. This Study Will Be to Evaluate the Effectiveness of a Telematic Cognitive-behavioral Preventive Intervention to Manage Anxiety During Pregnancy.Not yet recruitingNCT06609291Not applicable1 country
- The Effectiveness of Transdiagnostic CBT Protocol on Anxiety DisordersRecruitingNCT06422728Not applicable1 country
- Schema Therapy for Treatment-resistant Anxiety DisordersNot yet recruitingNCT06298695Not applicable
- Risk and Resiliency Factors in the RCMP: A Prospective InvestigationRecruitingNCT05527509Not applicable1 country
- Essential Hypotension and Allostasis RegistryRecruitingNCT020184971 country
- Development of Online EMDR Therapy System and Its Comparative Testing With Face-to-Face EMDR Therapy for Treatment of Anxiety and Depressive Disorders in PakistanNot yet recruitingNCT05785312Not applicable1 country
- Efficacy of Hydroxyzine for Patients With Panic DisorderNot yet recruitingNCT05737511Phase 4
- Neurobiological Markers of Treatment Response for Anxiety and OCDRecruitingNCT056634891 country
- Testing a Precision Psychotherapy System for Low-income PatientsNot yet recruitingNCT05118594Not applicable
- IL-33, sST2, and CRP in Panic DisorderCompletedNCT074448791 country
- Effects and Cost-effectiveness of e-Meistring - a Guided Internet-delivered Psychological TreatmentCompletedNCT058681351 country
- Feasibility and Preliminary Outcomes of Compassion-Focused Group Therapy for Depression and AnxietyCompletedNCT07876453Not applicable1 country
- Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBTCompletedNCT04029740Not applicable1 country
- Dexmedetomidine Nasal Spray for the Treatment of Panic Attacks in AdultsCompletedNCT07162649Not applicable1 country
- Psychoeducation Based on Acceptance and Commitment TherapyCompletedNCT06704399Not applicable1 country
- Evaluation of the Genetics of Bipolar DisorderCompletedNCT000011741 country
- Efficacy and Safety of HB-1 for Panic DisorderTerminatedNCT06483789Phase 21 country
- The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and TeensTerminatedNCT02998502Not applicable1 country
- Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive DisorderActive, not recruitingNCT05967468Not applicable1 country
- Imagery Rescripting for Traumatic Panic Attack MemoriesCompletedNCT07769996Not applicable1 country
- Evaluating Clinical Routines for ICBTCompletedNCT05321628Not applicable1 country
- Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCDActive, not recruitingNCT07024758Not applicable1 country