An interventional study of Parent Coached Exposure Therapy and Family Based, Internet-Based Cognitive Behavioral Therapy in Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence and Social Anxiety Disorder of Childhood, sponsored by Baylor College of Medicine. Active, not recruiting at 1 site in United States. Open to participants aged 7 Years to 17 Years. Per ClinicalTrials.gov, last updated 2026-07-30.
Sponsored by Baylor College of Medicine · Not applicable, Interventional, and Treatment
Among 16 studies in Obsessive-Compulsive Disorder by Baylor College of Medicine — 4 open to participants now, 12 under way, none of them phase 3. Obsessive-Compulsive Disorder · Baylor College of Medicine.
Among the 16 studies in Obsessive-Compulsive Disorder by Baylor College of Medicine, this one is the 2nd largest by planned enrollment of the 13 interventional ones, is one of 2 that started in 2025, is one of 13 with no phase, reaches primary completion later than 9 of the 11 other live ones, and was the 16th registered.
635 studies on the registry are indexed under Obsessive-Compulsive Disorder; 166 are open to participants now.
This study's planned enrollment of 174 is above the median of 45 across 520 interventional studies indexed under Obsessive-Compulsive Disorder.
Browse Obsessive-Compulsive Disorder studies →4 of the 16 studies in Obsessive-Compulsive Disorder by Baylor College of Medicine are open now, in 1 country. Each count lists the studies.
Of the 120 Obsessive-Compulsive Disorder studies recruiting now, 31 (26%) set no upper age limit and 81 (68%) stop at 75 or younger; 28 take children under 18; 18 take healthy volunteers.
This study: 7 Years to 17 Years · all sexes · no healthy volunteers.
The full table on the hub →16 studies; the count open now beside each. This study's row is marked.
First in 2018; this study’s year is marked. 2 started in 2025.
Median enrollment 68 across the 13 interventional studies, 20 across the 3 observational. Of the 4 that completed or were terminated, 3 (75%) have results posted.
Baylor College of Medicine is the lead sponsor of 747 studies on the registry; 110 are open to participants now.
Of its 84 completed or terminated interventional studies of FDA-regulated products, 45 (54%) have results posted.
7 of the studies in Obsessive-Compulsive Disorder by Baylor College of Medicine that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT04281134Baylor College of MedicineDevelopment of Adaptive Deep Brain Stimulation for OCD | 2027-06 |
| NCT03457675Baylor College of MedicineDevelopment of Adaptive Deep Brain Stimulation for OCD (Phase 1a) | 2027-06 |
| NCT05915741Baylor College of MedicineBrain Recordings in Patients Undergoing Deep Brain Stimulation (DBS) for Severe Obsessive-Compulsive Disorder (OCD) | 2027-06-01 |
| NCT03459456Baylor College of MedicineMeasuring Automated Behavioral Observations & Vocal Expressions (ABOVE) | 2027-07 |
| NCT04806516Baylor College of MedicinePhase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder | 2027-07-30 |
Among the 16 studies in Obsessive-Compulsive Disorder by Baylor College of Medicine, from their registry updates:
Nothing recorded among them since 2026-09-25.
Anxiety disorders in children and adolescents are common and confer significant disability. Cognitive behavioral therapy (CBT) is the recommended treatment for youth with anxiety, yet many families cannot access CBT due to cost, practicalities of attending in-person treatment sessions, and a shortage of trained providers, especially in rural areas. To combat these barriers, other treatment methods have been developed.
Previous research has shown that family-based, internet-delivered CBT (iCBT) for anxiety and OCD in youth has shown a significant reduction in anxiety symptoms. Parent-coached exposure therapy (PCET) focuses entirely on teaching parents and youth together how to address anxiety through the completion of in-session parent-coached exposures and assigning parent-coached exposure as homework in between sessions.
Although both iCBT and PCET show positive results in treating pediatric anxiety in comparison to standard-care CBT, little is known about the comparative efficacy of iCBT and PCET.
This research is being done to understand the comparative effectiveness of two different types of cognitive-behavioral therapy (CBT) for treating anxiety or OCD in youth.
Anxiety disorders in children and adolescents are common and confer significant disability. Without treatment, anxiety remains chronic and contributes to increased risk for later suicidality, mood, and substance use disorders. Cognitive behavioral therapy (CBT) is the recommended treatment for youth with anxiety, yet many families cannot access CBT due to cost, practicalities of attending in-person treatment sessions, and a shortage of trained providers, especially in rural areas. To combat these barriers, other treatment methods have been developed.
Low intensity telehealth delivery of services is a promising method to improve access to care for youth with anxiety and their families, given its reachability to a wider range of areas (e.g., rural/underserved) and its ability to minimize practical barriers (e.g., treatment could be delivered to the youth's home without need for travel), and reduce stigma (e.g., parents do not need to visit mental health clinics). Previous research has shown that family-based, internet-delivered CBT (iCBT) for anxiety and OCD in youth has shown a significant reduction in anxiety symptoms.
Parent-coached exposure therapy (PCET) focuses entirely on teaching parents and youth together how to address anxiety through the completion of in-session parent-coached exposures and assigning parent-coached exposure as homework in between sessions. PCET is designed to treat anxiety more effectively and efficiently, allowing for fewer sessions and greater symptom remission than standard-care CBT.
Although both iCBT and PCET show positive results in treating pediatric anxiety in comparison to standard-care CBT, little is known about the comparative efficacy of iCBT and PCET.
This research is being done to understand the comparative effectiveness of two different types of cognitive-behavioral therapy (CBT) for treating anxiety or OCD in youth.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Clinically significant
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Parent Coached Exposure Therapy (PCET) consists of 12 weekly individual sessions that are attended by the therapist, child, and parent. Sessions will follow the cognitive behavioral therapy model of childhood anxiety disorders, wherein safety behaviors and avoidance reinforce anxiety, explains the rationale of exposure, and begins developing an exposure hierarchy with the family. Sessions will include psychoeducation, developing an exposure hierarchy, carrying out in-session exposures, and assigning exposures in between sessions.
Behavioral: Parent Coached Exposure Therapy
One half of participants will be randomized to receive iCBT. Each week of treatment, the parent will be encouraged to read the corresponding materials on the Baylor College of Medicine (BCM) webpage, complete accompanying worksheets, and guide their child through completing activities in the child-facing materials, with support from a therapist (7 45-minute supportive therapy sessions). One core aspect of treatment will be parents leading their child through graduated exposure. Exposures, a hallmark of CBT for anxiety, are used to gradually and repeatedly confront feared stimuli. For example, exposure therapy for a child fearful of dogs may begin with looking at pictures of dogs and standing across the park from a dog on a leash, to eventually petting a dog. All relevant information regarding parent-led exposures will be detailed in the treatment materials, and therapists will review with parents via email and/or video-conferencing sessions.
Behavioral: Family Based, Internet-Based Cognitive Behavioral Therapy
Parent-based cognitive behavioral therapy with guidance from a therapist
Family-based cognitive behavioral therapy employing internet-delivered modules and videos
Change in clinician-rated child anxiety severity (PARS) throughout the past week.
Each item is scored on a 0 to 5 scale (higher scores correspond to greater severity), yielding a total between 0 and 30.
Time frame: baseline (before treatment or week 1), post-treatment (week 14), 1 month follow up (Week 18)
Diagnostic Interview for Anxiety, Mood, and OCD and Related Neuropsychiatric Disorders (DIAMOND) with Clinical Severity Ratings
Clinician-rated diagnostic interview that includes current anxiety disorders, mood disorders, obsessive-compulsive disorder, and related neuropsychiatric disorders. Each diagnostic category is coded as present or absent based on symptom criteria and severity scale. Severity scales are scored on a 1-7 scale (1 = normal; 7 = extreme) and are based on current level of distress and impairment (within the past month).
Time frame: baseline (before treatment or week 1), post-treatment (week 14), 1 month follow up (Week 18)
Clinical Global Impression-Severity
Clinician-rated child psychopathology severity rating. A single item is scored 0-6 (0= no illness; 6= extremely severe symptoms).
Time frame: baseline (before treatment or Week 1), during treatment (on average 14 weeks), post-treatment (Week 14), 1 month follow up (Week 18)
Plan to share: No
This study is active, not recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Obsessive-Compulsive Disorder →