Drug
Paroxetine clinical trials
Also written Paxil and Paxil CR.
Includes 4 studies of Paroxetine mesylate.
- studies test it
- 122
- open now
- 3
- in phase 3
- 23
- first study started
- 1997
Keep track of what changes. Save the Paroxetine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Studies by the year they started
119 studies that test it; most in 2005 (11)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 1998 | 1 |
| 1999 | 2 |
| 2000 | 2 |
| 2001 | 3 |
| 2002 | 10 |
| 2003 | 7 |
| 2004 | 10 |
| 2005 | 11 |
| 2006 | 9 |
| 2007 | 2 |
| 2008 | 9 |
| 2009 | 5 |
| 2010 | 3 |
| 2011 | 4 |
| 2012 | 2 |
| 2013 | 2 |
| 2014 | 3 |
| 2015 | 2 |
| 2016 | 3 |
| 2017 | 2 |
| 2018 | 1 |
| 2019 | 4 |
| 2020 | 4 |
| 2021 | 4 |
| 2022 | 3 |
| 2023 | 3 |
| 2024 | 3 |
| 2025 | 3 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 24
- Phase 2
- 20
- Phase 3
- 23
- Phase 4
- 40
- No phase
- 16
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 49 · Other 73
GlaxoSmithKline (21) · Noven Therapeutics (4) · US Department of Veterans Affairs (4) · Emory University (3) · University of Pittsburgh (3) · Wyeth is now a wholly owned subsidiary of Pfizer (3) · University of California, Irvine (2) · Central South University (2)
Often tested with
Tested in the same studies.
Venlafaxine (6) · Nortriptyline (5) · Duloxetine (5) · Fluvoxamine (4) · Amitriptyline (4) · Sertraline (4) · Citalopram (4) · Mirtazapine (4)
Studies
Open first, then newest update. How each study uses Paroxetine is read from its arms, and is right about nine times in ten.
Testing it · 122
- Antidepressant Therapy for Improved Blood Vessel Health After PreeclampsiaRecruitingEarly Phase 1Anna Stanhewicz, PhDNCT07715669Written as Paroxetine Hydrochloride
- Therapeutic Outcomes of Selective Serotonin Reuptake Inhibitors and Phosphodiesterase-5 Inhibitors Combination Therapy Versus MonotherapyNot yet recruitingNot applicableSouth Valley UniversityNCT07057011Written as Paroxetine 20 Mg Oral Tablet
- The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes MellitusNot yet recruitingPhase 3aya ramadan ashmawy sarhanNCT06203275Written as Paroxetine
- Effects of Paroxetine on Cardiovascular Function in Septic PatientsCompletedPhase 2Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da SaudeNCT05725837Written as Paroxetine
- Concentration-QT Study of Paroxetine in Healthy AdultsCompletedPhase 1GlaxoSmithKlineNCT06065735Written as Paroxetine
- Transcutaneous Posterior Tibial Nerve Stimulation for Premature EjaculationCompletedNot applicableBoston Medical GroupNCT04207723Written as Paroxetine
- Paroxetine Safety and Efficacy in Rheumatoid ArthritisCompletedPhase 3Mostafa BahaaNCT06231745Written as Paroxetine
- Treatment of Tinnitus With Migraine MedicationsCompletedPhase 4University of California, IrvineNCT04404439Written as Verapamil + Paroxetine
- Management of Acute Tinnitus With Migraine MedicationsActive, not recruitingPhase 4University of California, IrvineNCT06799169Written as Paroxetine
- Paroxetine Versus Placebo for Vasomotor Symptom Management in Surgical MenopauseCompletedPhase 2Universidad Nacional Autonoma de HondurasNCT06763484Written as Paroxetine
- The GRK2 Inhibitor Paroxetine as a Novel Adjunct to Conventional Therapy in Rheumatoid Arthritis PatientsWithdrawnPhase 1/2Sadat City UniversityNCT04757571Written as Paroxetine
- Effect of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on VentilationCompletedPhase 1Food and Drug Administration (FDA)NCT05470465Written as Paroxetine and Oxycodone
- Drug-Drug Interaction of ASN51 With Fluvoxamine, Itraconazole and Paroxetine in Healthy SubjectsCompletedPhase 1Asceneuron S.A.NCT06232109Written as Paroxetine
- Definitive Selection of Neuroimaging Biomarkers for the Diagnosis and Treatment to Common Mental DisordersCompletedNot applicableCentral South UniversityNCT04218981Written as Paroxetine
- Definitive Selection of Neuroimaging Biomarkers in Anxiety Disorder and Obsessive-compulsive Disorder: A Longitudinal Functional Magnetic Resonance Imaging （fMRI） Study With Paroxetine TreatmentCompletedNot applicableCentral South UniversityNCT03894085Written as Paroxetine
- Paroxetine Hydrochloride 40 mg Tablets Under Fed ConditionsCompletedPhase 1Teva Pharmaceuticals USANCT00841659Written as Paroxetine HCl
- Paroxetine Hydrochloride 40 mg Tablets Under Fasting ConditionsCompletedPhase 1Teva Pharmaceuticals USANCT00841698Written as Paroxetine HCl
- Food Study of Paroxetine Hydrochloride Tablets 40 mg and Paxil® Tablets 40 mgCompletedPhase 1Mylan Pharmaceuticals IncNCT00650403Written as Paroxetine hydrochloride 40 mg tablet
- Fasting Study of Paroxetine Hydrochloride Tablets 40 mg and Paxil® Tablets 40 mgCompletedEarly Phase 1Mylan Pharmaceuticals IncNCT00648193Written as Paroxetine hydrochloride 40 mg tablet
- Effects of SERT Inhibition on the Subjective Response to LSD in Healthy SubjectsCompletedPhase 1University Hospital, Basel, SwitzerlandNCT05175430Written as Paroxetine
See all 122 studies that test Paroxetine →
Given in every arm · 9 — Paroxetine is usual care beside what is tested
- A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant TumorsRecruitingPhase 1/2BioNTech SENCT07070232Written as Paroxetine
- A Phase I Study of NS-079 in Healthy ParticipantsRecruitingPhase 1NeuShen TherapeuticsNCT07669571Written as Paroxetine
- Quetiapine Augmentation for Treatment-resistant PTSDCompletedPhase 4VA Office of Research and DevelopmentNCT00292370Written as Open Label (OL) Paroxetine
- Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial)CompletedPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT01360866Written as Paroxetine CR
- Adding Cognitive Behavioral Therapy to Drug Treatment for Social Anxiety DisorderCompletedPhase 3Temple UniversityNCT00074802Written as Paroxetine
- Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of ClomipheneCompletedPhase 1Robert Bosch Gesellschaft für Medizinische Forschung mbHNCT01289756Written as clomiphene and paroxetine
- Randomized，Controlled and Open-label Study of Buspirone add-on Treatment in Patients With Major Depression DisorderStatus unknownPhase 4Si TianmeiNCT02273154Written as Paroxetine
- Interpersonal Psychotherapy for Treatment Resistant DepressionStatus unknownNot applicableHospital de Clinicas de Porto AlegreNCT01896349Written as paroxetine
- Lamotrigine Augmentation in Resistant DepressionCompletedNot applicableLouisiana State University Health Sciences Center in New OrleansNCT00901407Written as paroxetine
As the comparator · 24 — what is tested is compared with Paroxetine
- Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth SyndromeRecruitingPhase 3Federico II UniversityNCT06025474Written as Paroxetine 20 Mg Oral Tablet
- Lithium Versus Paroxetine in Major DepressionWithdrawnPhase 4Nova Scotia Health AuthorityNCT01416220Written as Paroxetine
- Fasting Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mgCompletedPhase 1Mylan Pharmaceuticals IncNCT00648427Written as Paxil CR™ Tablets 25 mg
- Food Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mgCompletedPhase 1Mylan Pharmaceuticals IncNCT00647881Written as Paxil CR™ Tablets 25 mg
- Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic AssessmentCompletedPhase 4Azienda Ospedaliera Universitaria Integrata VeronaNCT03779789Written as Paroxetine
- Lithium Versus Paroxetine in Patients With Major Depression Who Have a Family History of Bipolar Disorder or SuicideTerminatedPhase 3Nova Scotia Health AuthorityNCT00400088Written as paroxetine
- A Study Of Sertraline Compared With Paroxetine In The Treatment Of Panic DisorderCompletedPhase 4Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT00677352Written as Paroxetine
- A Placebo- and Paroxetine-controlled Study of the Efficacy, Safety and Tolerability of Agomelatine (25 or 50 mg) in the Treatment of Major Depressive Disorder (MDD)CompletedPhase 3NovartisNCT00463242Written as paroxetine
- Effects of MNTX on CYP450 2D6 in Metabolizers of DextromethorphanCompletedPhase 1Bausch Health Americas, Inc.NCT01367535Written as Oral Paroxetine
- Fixed Dose Study of PD 0332334 and Paroxetine for the Treatment of Generalized Anxiety DisorderTerminatedPhase 3Cedars-Sinai Medical CenterNCT00836069Written as Paroxetine
- Effect of Vortioxetine, Paroxetine, and Placebo on Sexual Functioning in Healthy VolunteersCompletedPhase 4TakedaNCT02932904Written as Paroxetine
- Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep DisturbanceTerminatedNot applicableSeattle Institute for Biomedical and Clinical ResearchNCT00202449Written as paroxetine
- Efficacy of Vortioxetine on Cognitive Dysfunction in Working Patients With Major Depressive DisorderCompletedPhase 3H. Lundbeck A/SNCT02279966Written as Paroxetine 20 mg
- Controlled-release Paroxetine in Major Depressive Disorder (Double-blind, Placebo-controlled Study)CompletedPhase 3GlaxoSmithKlineNCT00866294Written as paroxetine IR 10mg tablet
- An Eight-week Study Evaluating the Efficacy and Tolerability of Two Doses of SSR149415 in Outpatients With Generalized Anxiety DisorderCompletedPhase 2SanofiNCT00374166Written as Paroxetine
- Study to Evaluate the Sexual Functioning of Healthy Adults After Receiving Vilazodone, Paroxetine or PlaceboCompletedPhase 1Forest LaboratoriesNCT02097147Written as Paroxetine 20 mg
- Paroxetine-referenced Study Evaluating Three Doses of DVS SR in Outpatients With MDDCompletedPhase 3Wyeth is now a wholly owned subsidiary of PfizerNCT00445679Written as Paroxetine
- Algorithm Guided Treatment Strategies for Major Depressive DisorderStatus unknownPhase 4Shanghai Mental Health CenterNCT01764867Written as Paroxetine
- A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 for the Treatment of Generalized Anxiety Disorder (3)TerminatedPhase 3PfizerNCT00658762Written as paroxetine
- A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder (2)TerminatedPhase 3PfizerNCT00658372Written as Paroxetine
Showing 20 of 24.
Codes
What other systems call Paroxetine · ClinicalTrials.gg INT008600
- MeSH (NLM) D017374ParoxetineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 41VRH5220HPAROXETINEConfirmed FDA, NLM, Wikidata
- RxNorm 32937Confirmed FDA, Wikidata
- Wikidata Q27257245paroxetine hydrochlorideConfirmed FDA, NLM, Wikidata
- Wikidata Q408471paroxetineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61879ParoxetineOne source FDA
- DrugBank DB00715One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D017374 | Paroxetine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 41VRH5220H | PAROXETINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 32937 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27257245 | paroxetine hydrochloride | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q408471 | paroxetine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61879 | Paroxetine | One source FDA |
| DrugBank | DB00715 | — | One source Wikidata |
Also registered as paroxetine acetate (UNII YPO0NTK49O), paroxetine hydrochloride (UNII X2ELS050D8 · RxNorm 1298842), paroxetine hydrochloride anhydrous (UNII 3I3T11UD2S · RxNorm 1311626) and paroxetine maleate (UNII F726G2563Q).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.