Drug
Venlafaxine clinical trials
Also written Effexor.
Includes 9 studies of Venlafaxine Hydrochloride Extended Release.
Keep track of what changes. Save the venlafaxine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
118 studies that test it; most in 2002 (11)
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1996 | 1 |
| 1999 | 2 |
| 2000 | 2 |
| 2001 | 6 |
| 2002 | 11 |
| 2003 | 5 |
| 2004 | 11 |
| 2005 | 7 |
| 2006 | 6 |
| 2007 | 6 |
| 2008 | 6 |
| 2009 | 5 |
| 2010 | 1 |
| 2011 | 5 |
| 2012 | 7 |
| 2013 | 4 |
| 2014 | 2 |
| 2015 | 4 |
| 2016 | 3 |
| 2017 | 1 |
| 2018 | 2 |
| 2019 | 1 |
| 2020 | 3 |
| 2021 | 2 |
| 2022 | 2 |
| 2023 | 3 |
| 2024 | 3 |
| 2025 | 4 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 36 · Other 84
Wyeth is now a wholly owned subsidiary of Pfizer (16) · New York State Psychiatric Institute (6) · University of California, Los Angeles (5) · Teva Pharmaceuticals USA (5) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (4) · Eli Lilly and Company (4) · Massachusetts General Hospital (3) · Mayo Clinic (3)
Often tested with
Tested in the same studies.
Sertraline (14) · Escitalopram (8) · Citalopram (7) · Duloxetine (7) · Paroxetine (6) · Fluoxetine (5) · Bupropion (4) · Aripiprazole (3)
Related medicines
As reviewed, each with the page that says it.
Studies
Open first, then newest update. How each study uses venlafaxine is read from its arms, and is right about nine times in ten.
Testing it · 120
- The Efficacy and Safety of Pregabalin Combined With Venlafaxine in Patients With FibromyalgiaRecruitingNot applicableBeijing Tiantan HospitalNCT07186751Written as Pregabalin with venlafaxine
- Venlafaxine for Non-specific Low Back PainNot yet recruitingNot applicableBeijing Tiantan HospitalNCT07737158Written as Venlafaxine group
- Venlafaxine as Adjunct Therapy in Rheumatoid ArthritisNot yet recruitingPhase 2Ain Shams UniversityNCT07497282Written as venlafaxine extended-release (XR)
- Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment FailureRecruitingPhase 3Dr. Inge WinterNCT05603104Written as Venlafaxine
- The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.RecruitingPhase 3Dr. Inge WinterNCT05973786Written as Venlafaxine
- Effect of Venlafaxine Versus Dosulepin in Pain Predominant Somatic Symptom DisorderRecruitingPhase 4All India Institute of Medical Sciences, BhubaneswarNCT06803485Written as Venlafaxine
- Pragmatic Trial of Obsessive-compulsive DisorderRecruitingPhase 2Shanghai Mental Health CenterNCT04539951Written as Venlafaxine
- REDucing Hot FLASHes in Women Using Endocrine Therapy.RecruitingPhase 3Reinier de Graaf GroepNCT06106529Written as Venlafaxine
- The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN)RecruitingPhase 4Fondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoNCT06131268Written as Venlafaxine
- Venlafaxine for Postoperative Pain of Laparoscopic CholecystectomyNot yet recruitingPhase 1/2Mansoura UniversityNCT05884268Written as Venlafaxine
- Preventive Approach Using VenlafaxineRecruitingPhase 4Mit Ghamr Oncology CenterNCT05875610Written as Venlafaxine 75 MG
- Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRDCompletedPhase 4Massachusetts General HospitalNCT02977299Written as Venlafaxine XR
- Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep ApneaCompletedPhase 4China Medical University HospitalNCT06295562Written as Venlafaxine 37.5mg
- Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation TherapyCompletedPhase 2Roswell Park Cancer InstituteNCT03574792Written as Venlafaxine
- Physiologic Monitoring of Antidepressant ResponseCompletedPhase 4University of California, Los AngelesNCT00792168Written as venlafaxine (Effexor)
- Beta-arrestins and Response to Venlafaxine in Major Depressive Disorder (MDD) (DEPARRESTCLIN)CompletedPhase 4Institut National de la Santé Et de la Recherche Médicale, FranceNCT02051413Written as Venlafaxine extended release
- The Use of Venlafaxine in Reducing Pain in Primary Total Knee ReplacementCompletedPhase 4University of California, San FranciscoNCT05023278Written as Venlafaxine 37.5 MG
- Feasibility Trial of Tele-IPT and Tele-Pharmacotherapy for Patients With Depression and Non-Metastatic Breast CancerSuspendedPhase 3New York State Psychiatric InstituteNCT04973930Written as Venlafaxine HCl ER
- Mood Disorders in Head and Neck Cancer PatientsWithdrawnPhase 4University of Alabama at BirminghamNCT04977271Written as Venlafaxine
- Venlafaxine and Hypnosis or Focused Attention in Treating Patients with Hot FlashesCompletedNot applicableMayo ClinicNCT01000623Written as venlafaxine
See all 120 studies that test venlafaxine →
Given in every arm · 19 — venlafaxine is usual care beside what is tested
- A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant DepressionCompletedPhase 3Janssen Research & Development, LLCNCT02493868Written as Venlafaxine Extended Release (XR) (Oral Antidepressant)
- A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant DepressionCompletedPhase 3Janssen Research & Development, LLCNCT02422186Written as Venlafaxine Extended Release (XR) (New Antidepressant)
- A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionCompletedPhase 3Janssen Research & Development, LLCNCT03434041Written as Venlafaxine Extended Release (XR) (Oral Antidepressant)
- A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionCompletedPhase 3Janssen Research & Development, LLCNCT02417064Written as Venlafaxine Extended Release (XR) (Oral Antidepressant)
- A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant DepressionCompletedPhase 3Janssen Research & Development, LLCNCT02497287Written as Venlafaxine Extended Release (XR) (Oral Antidepressant)
- A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionCompletedPhase 3Janssen Research & Development, LLCNCT02418585Written as Venlafaxine Extended Release (XR) (Oral Antidepressant)
- Accurate Clinical Study of Medication in Patients With Depression Via Pharmacogenomics (PGx) and Therapeutic Drug Monitoring (TDM) of VenlafaxineStatus unknownPhase 4Xijing HospitalNCT04207385Written as Venlafaxine
- Buprenorphine Used With Treatment Resistant Depression in Older AdultsCompletedPhase 1/2Washington University School of MedicineNCT02181231Written as venlafaxine XR
- Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial)CompletedPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT01360866Written as Venlafaxine XR
- Incomplete Response in Late-Life Depression: Getting to Remission With BuprenorphineCompletedPhase 1/2Centre for Addiction and Mental HealthNCT02263248Written as venlafaxine
- A Multi-level Life-span Characterization of Adult-depression and Effects of Medication and ExerciseCompletedPhase 4Kirk Erickson, PhDNCT02407704Written as Venlafaxine XR
- ADAPT: Addressing Depression and Pain TogetherCompletedPhase 4University of PittsburghNCT01124188Written as Higher-dose venlafaxine
- Combined Treatment for Generalized Anxiety Disorder (GAD)CompletedPhase 2University of PennsylvaniaNCT00620776Written as Venlafaxine XR
- Venlafaxine Augmentation in Treatment Resistant DepressionCompletedPhase 4Max-Planck-Institute of PsychiatryNCT00253266Written as Venlafaxine
- Combination of Antidepressants and Fingolimod Relapsing-remitting Multiple Sclerosis (RRMS) Patients With DepressionTerminatedPhase 4Novartis PharmaceuticalsNCT01436643Written as Venlafaxine
- Interpersonal Psychotherapy for Treatment Resistant DepressionStatus unknownNot applicableHospital de Clinicas de Porto AlegreNCT01896349Written as Venlafaxine
- Antidepressant Medication Plus Donepezil for Treating Late-life DepressionCompletedPhase 4University of PittsburghNCT00177671Written as Venlafaxine
- Randomised Controlled Trial of Electroconvulsive Therapy (ECT) in Relapse Prevention of DepressionCompletedPhase 4Örebro County CouncilNCT00627887Written as venlafaxine
- A Study of Eszopiclone Co-administered With Venlafaxine in Subjects With Major Depressive Disorder and InsomniaCompletedPhase 3Sumitomo Pharma America, Inc.NCT00435279Written as Venlafaxine
As the comparator · 16 — what is tested is compared with venlafaxine
- A Safety and Efficacy Study of JNJ26489112 in Patients With Treatment-Resistant Major Depressive DisorderTerminatedPhase 2Janssen Research & Development, LLCNCT01114698Written as Venlafaxine XR
- Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive AbilitiesStatus unknownPhase 3Scotmann PharmaceuticalsNCT05104918Written as Venlafaxine
- A Comparison of Sertraline Versus Venlafaxine XR in the Treatment of Major DepressionCompletedPhase 4Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT00644982Written as venlafaxine XR
- Acupuncture for Prophylaxis of Vestibular MigraineStatus unknownNot applicableAffiliated Hospital of Jiaxing UniversityNCT04664088Written as Venlafaxine
- Bioequivalence Study of Venlafaxine Hydrochloride Sustained-Release Capsules in Chinese Healthy VolunteersStatus unknownNot applicableBeijing Tongren HospitalNCT04229602Written as EFEXOR® XR
- Prolonging Remission in Depressed Elderly (PRIDE)CompletedPhase 4Icahn School of Medicine at Mount SinaiNCT01028508Written as lithium and Venlafaxine
- Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six WeeksCompletedPhase 3University Hospital, GrenobleNCT01557712Written as Venlafaxine
- Trazodone Once a Day in Major Depression DisorderCompletedPhase 3Aziende Chimiche Riunite Angelini Francesco S.p.ANCT02086929Written as Venlafaxine
- Effect of Antidepressants on the Treatment for Korean Major Depressive Disorder PatientsTerminatedPhase 4Ministry of Health & Welfare, KoreaNCT00926835Written as Venlafaxine XR
- Study of Vortioxetine (Lu AA21004) in Major Depressive Disorder in Asian CountriesCompletedPhase 3H. Lundbeck A/SNCT01571453Written as Venlafaxine extended release
- A Study Of New Medicine (GSK 372475) For The Treatment Of DepressionCompletedPhase 2GlaxoSmithKlineNCT00448058Written as venlafaxine
- Randomised Placebo-controlled Venlafaxine-referenced Study of Efficacy and Safety of 5 and 10 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in AdultsCompletedPhase 2H. Lundbeck A/SNCT00839423Written as Venlafaxine XL
- Algorithm Guided Treatment Strategies for Major Depressive DisorderStatus unknownPhase 4Shanghai Mental Health CenterNCT01764867Written as Venlafaxine
- Kava Kava for the Treatment of Generalized Anxiety Disorder (GAD)TerminatedPhase 2National Center for Complementary and Integrative Health (NCCIH)NCT00083980Written as Venlafaxine ER
- A Safety, Efficacy and Tolerability Study of SEP-225289CompletedPhase 2Sumitomo Pharma America, Inc.NCT00584974Written as Venlafaxine
- Efficacy and Safety of Lu AA34893 in Patients With Major Depressive DisorderTerminatedPhase 2H. Lundbeck A/SNCT00766870Written as Venlafaxine extended release
Codes
What other systems call venlafaxine · ClinicalTrials.gg INT006595
- MeSH (NLM) D000069470Venlafaxine HydrochlorideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) GRZ5RCB1QGVENLAFAXINEConfirmed FDA, NLM, Wikidata
- RxNorm 39786Confirmed FDA, Wikidata
- Wikidata Q898407venlafaxineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1278VenlafaxineOne source FDA
- DrugBank DB00285One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069470 | Venlafaxine Hydrochloride | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | GRZ5RCB1QG | VENLAFAXINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 39786 | — | Confirmed FDA, Wikidata |
| Wikidata | Q898407 | venlafaxine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1278 | Venlafaxine | One source FDA |
| DrugBank | DB00285 | — | One source Wikidata |
Also registered as venlafaxine hydrochloride (UNII 7D7RX5A8MO · RxNorm 235988).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.