ClinicalTrials.gg
Sign In

Metabolic Diseases clinical trials

The registry lists 763 studies for Metabolic Diseases across more than 10 countries. 192 are recruiting or about to start. 165 of them are mainly about Metabolic Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 169 narrower conditions too, such as Diabetes Mellitus, Type 2: 45,559 studies, 7,680 open.

ClinicalTrials.gov finds 53,019 studies for Metabolic Diseases. How that becomes 764 here

This page counts the studies the registry files under Metabolic Diseases, and those it files under no condition that list Metabolic Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 53,019Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −36,554Filed under a narrower condition, counted on its own pageDiabetes Mellitus, Type 2 9,918 · Diabetes Mellitus 6,153 · Diabetes Mellitus, Type 1 2,616 · Insulin Resistance 1,885 · Osteoporosis 1,477 · Metabolic Syndrome 1,459 · 151 more
  3. −47List Metabolic Diseases as a condition, but the registry did not file them under itMost often written as “Nutritional and Metabolic Diseases” (31), “MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)” (7), and “Free of Metabolic Disease” (1). The registry filed 9 of them under no condition at all, and the others under other conditions only, most often Nutritional and Metabolic Diseases (31) and Obesity (7).
  4. −15,654Match it another way24 name it in the title, 3 in a keyword, and 15,627 by a synonym or other text the search reads.
  5. 764The count on this page

Get an email when these change. Save the Metabolic Diseases studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

Watch these studies
See an example email

Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Status

Completed
384
Recruiting
133
Status unknown
69
Active, not recruiting
49
Not yet recruiting
47
Terminated
40

Phase

Phase 2
97
Phase 1
79
Phase 3
68
Phase 4
19
Early Phase 1
3

Where

United States
272
Canada
67
United Kingdom
61
China
57
France
55
Denmark
46

Who runs them

Eli Lilly and Company (18) · Pfizer (10) · Massachusetts General Hospital (10) · University of Aarhus (9) · AstraZeneca (8) · KK Women's and Children's Hospital (7) · Singapore Institute of Food and Biotechnology Innovation (7) · University of Copenhagen (6)

What is being tested here

Drugs under test in Metabolic Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Pegozafermin235
Berobenatide233
Nicotinamide-beta-riboside202
Tirzepatide147
Vericiguat101
Puerarin101
Henagliflozin101
Terazosin101
Bicalutamide101
Zodasiran111

Drug classes tested here GLP-1 receptor agonists 3 open · SGLT2 inhibitors 8 · DPP-4 inhibitors 8 · Statins 5

Coming up

18phase 3 studies under way
59studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 133 Metabolic Diseases studies recruiting now, 47 (35%) set no upper age limit and 63 (47%) stop at 75 or younger. 38 (29%) take children under 18. 9 (7%) are for women only and 2 (2%) for men only; 50 (38%) take healthy volunteers.

Recruiting studies that take each age, of 133
AgeWomenMen
1028 (21%)29 (22%)
18109 (82%)106 (80%)
30106 (80%)102 (77%)
40109 (82%)106 (80%)
50106 (80%)102 (77%)
65100 (75%)96 (72%)
7581 (61%)77 (58%)
8561 (46%)58 (44%)

Across all 763 studies, recruiting or not: 58% stop at 75 or younger and 44% at 65; 23% take children; 8% are for women only and 7% for men only; 39% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Metabolic Diseases studies take

Of 34 phase 3 interventional studies under Metabolic Diseases, half reached primary completion within 28 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 17 mo5–12 · 27 studies——
Phase 227 mo19–58 · 27 studies——
Phase 328 mo22–38 · 34 studies28 mo21–38 · 32 studies—
Interventional, no phase22 mo10–43 · 201 studies—22 mo10–44 · 182 studies
Observational135 mo23–339 · 101 studies—135 mo24–339 · 89 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting4

Newly registered4

Studies

Recruiting first, then most recently updated. Showing 50 of 763. Browse all 763 → or search them.