AstraZeneca: Metabolic Diseases trials

The registry lists 11 Metabolic Diseases studies with AstraZeneca as lead sponsor. 1 are open to participants now and 8 have results posted.

Phase 1 3Phase 2 2Phase 3 6No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy ParticipantsRecruitingNCT07723833Phase 1
• Study to Evaluate Safety and Efficacy of Dapagliflozin in Patients With Type 2 Diabetes Mellitus Aged 10-24 YearsCompletedNCT02725593Phase 3Results posted
• Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB)CompletedNCT02324049Phase 1/2Results posted
• Safety and Efficacy Study of Sebelipase Alfa in Participants With Lysosomal Acid Lipase DeficiencyCompletedNCT02112994Phase 2Results posted
• A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes With Inadequately Controlled Hypertension on an ACEI or ARB and an Additional Antihypertensive MedicationCompletedNCT01195662Phase 3Results posted
• A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes and Inadequately Controlled Hypertension on an Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor BlockerCompletedNCT01137474Phase 3Results posted
• Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 DiabetesCompletedNCT00859898Phase 3Results posted
• Safety and Efficacy of Dapagliflozin as Monotherapy in Subjects With Type 2 DiabetesCompletedNCT00736879Phase 3Results posted
• A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin AloneCompletedNCT00528879Phase 3Results posted
• A Study to Understand the Safety, Tolerability, and Activity of Drug in Body Over a Period of Time of AZD2693, in Subjects of Non-Childbearing Potential in Overweight But Otherwise Healthy Subjects, and Healthy Chinese and Japanese SubjectsCompletedNCT04142424Phase 1
• Evaluation of Blood Brain Barrier Integrity and Structural Abnormalities in MPS IIIB Patients Using Multimodal Magnetic Resonance ImagingCompletedNCT02090179