Glucose Metabolism Disorders clinical trials
The registry lists 361 studies for Glucose Metabolism Disorders across more than 10 countries. 38 are recruiting or about to start. 89 of them are mainly about Glucose Metabolism Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 23 narrower conditions too, such as Diabetes Mellitus, Type 2: 27,265 studies, 4,062 open.
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Status
Who runs them
Takeda (41) · Eli Lilly and Company (12) · University Hospital, Gentofte, Copenhagen (9) · Pfizer (7) · AstraZeneca (6) · Hvidovre University Hospital (6) · Ultragenyx Pharmaceutical Inc (5) · Maastricht University Medical Center (5)
What is being tested here
Drugs under test in Glucose Metabolism Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Metformin | 1 | 5 | 13 |
| Tirzepatide | 1 | 4 | 6 |
| Diazoxide | 1 | 0 | 4 |
| Liraglutide | 1 | 1 | 3 |
| Berobenatide | 1 | 2 | 2 |
| Interleukin 1 Receptor Antagonist Protein | 1 | 0 | 2 |
| Niacin | 1 | 0 | 2 |
| Semaglutide | 1 | 0 | 2 |
| Henagliflozin | 1 | 0 | 1 |
| Orforglipron | 1 | 1 | 1 |
Drug classes tested here GLP-1 receptor agonists 3 open · DPP-4 inhibitors 18 · SGLT2 inhibitors 9
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- May 2027A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting · Phase 3 · Eli Lilly and Company
- Oct 2027A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D) · Phase 3 · Pfizer
- Nov 2026Use of Continuous Glucose Monitoring in Non-Diabetic Population to Compliment Signos Mobile Health Platform · Signos Inc
- Nov 2026A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants · AstraZeneca
- Nov 2026Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers · Tides Medical
- Nov 2026Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs · C5 Biomedical
- Nov 2026A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease Type 1a (GSD1a) · ModernaTX, Inc.
- Dec 2026Evaluating a Digital Intervention for Alleviating Diabetes-specific Emotional Distress in Adults Living With T2DM · Gaia AG
- Dec 2026Henagliflozin's Impact on Prediabetes Remission · Shandong Provincial Hospital
- Dec 2026Continuous Glucose Monitoring Glycemic cHAracterization During Pregnancy · KK Women's and Children's Hospital
Who these studies take
Of the 29 Glucose Metabolism Disorders studies recruiting now, 9 (31%) set no upper age limit and 18 (62%) stop at 75 or younger. 7 (24%) take children under 18. 3 (10%) are for women only and 1 (3%) for men only; 11 (38%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (14%) | 4 (14%) |
| 18 | 21 (72%) | 20 (69%) |
| 30 | 24 (83%) | 24 (83%) |
| 40 | 24 (83%) | 24 (83%) |
| 50 | 23 (79%) | 24 (83%) |
| 65 | 20 (69%) | 20 (69%) |
| 75 | 12 (41%) | 12 (41%) |
| 85 | 9 (31%) | 9 (31%) |
Across all 361 studies, recruiting or not: 62% stop at 75 or younger and 36% at 65; 12% take children; 7% are for women only and 6% for men only; 37% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Glucose Metabolism Disorders studies take
Of 17 phase 3 interventional studies under Glucose Metabolism Disorders, half reached primary completion within 22 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 46 mo27–74 · 15 studies | — | — |
| Phase 3 | 22 mo17–28 · 17 studies | — | — |
| Interventional, no phase | 19 mo7–40 · 119 studies | — | 18 mo6–40 · 106 studies |
| Observational | 31 mo12–67 · 23 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
- Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary BypassNov 9, 2026NCT06861881
Results posted2
Studies
Recruiting first, then most recently updated. Showing 50 of 361. Browse all 361 → or search them.
- Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary BypassRecruitingNCT06861881Not applicable1 country
- A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or ObesityRecruitingNCT07595549Phase 311 countries
- Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring ProgramRecruitingNCT066363839 countries
- A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan FastingRecruitingNCT07613307Phase 34 countries
- Glycemic Control and Quality of Life Evolution for Patients With T1D Using the myLoop Powered by CamAPS FX System in Combination With FreeStyle Libre 3 / 3 Plus Sensors in FranceNot yet recruitingNCT07835685
- Reproducibility of Continuous Glucose Monitoring (CGM) in the Assessment of Glucose Metabolism Disorders in Children With Cystic FibrosisNot yet recruitingNCT07851831Not applicable1 country
- Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 DiabetesRecruitingNCT04874012Phase 21 country
- Acute Metabolic Effects of Tirzepatide in Type 1 DiabetesRecruitingNCT06820281Phase 21 country
- A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy ParticipantsRecruitingNCT07723833Phase 11 country
- METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)RecruitingNCT07699380Phase 22 countries
- A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes MellitusRecruitingNCT06575426Phase 1/21 country
- Bao Yuan Tang Extract and Galactooligosaccharides for Sleep RegulationNot yet recruitingNCT07774897Not applicable1 country
- Continuous Glucose Monitoring Glycemic cHAracterization During PregnancyRecruitingNCT06357728Not applicable1 country
- Brain Metabolism Observed at 3 Tesla or 7 Tesla in Health and Metabolic DiseaseRecruitingNCT050857041 country
- Anakinra for the Treatment of Postprandial Hypoglycemia in a Patient With Total Gastrectomy and End-Stage Renal DiseaseNot yet recruitingNCT07580079Phase 21 country
- Animal and Plant Proteins and Glucose MetabolismRecruitingNCT03994367Not applicable1 country
- Specificities of Atypical Non AutoImmune Diabetes (ANAID) in the French West IndiesNot yet recruitingNCT075763741 country
- Regulation of Endogenous Glucose Production by Central KATP ChannelsRecruitingNCT03540758Phase 21 country
- Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 DiabetesRecruitingNCT05543083Not applicable1 country
- The CGM-OGTT Glycemic Homeostasis StudyNot yet recruitingNCT07288372
- Utility of 18FDOPA PET/MRI for Focal HyperinsulinismRecruitingNCT05088798Phase 21 country
- The Effect of Chlorhexidine Mouthwash on Postprandial Glucose Response in Healthy IndividualsRecruitingNCT07172009Not applicable1 country
- Rare and Atypical Diabetes NetworkRecruitingNCT055442661 country
- Metabolic Effects of Endogenous Bile Acids After Gastric Bypass SurgeryRecruitingNCT06925997Early Phase 11 country
- Postprandial Metabolome and Metabolic FlexibilityRecruitingNCT06878781Not applicable1 country
- Impact of Chromium Supplementation on Glucido-lipidic Metabolism, Oxidative Stress and Inflammatory State in Patients with Gestational DiabetesNot yet recruitingNCT06860087Phase 1/21 country
- Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot UlcersRecruitingNCT06681428Not applicable1 country
- Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUsRecruitingNCT06674980Not applicable1 country
- Study of Time-restricted Eating (TRE) to Clinical Pregnancy Rate in PCOS Women With Glucose Metabolism Disorder Via IVF/ICSIEnrolling by invitationNCT06666933Not applicable1 country
- Relationship Between Individual Effect of Diet on Postprandial Glycemia and Gut Microbiome Profile in Healthy SubjectsRecruitingNCT06051318Not applicable1 country
- In-Person Lifestyle Program for Black Adolescent Girls at Risk for Type 2 DiabetesRecruitingNCT06557317Not applicable1 country
- Multidisciplinary Care for Lifestyle Change for Metabolic Control and Quality of Life in Prediabetes (PreCPro)RecruitingNCT06468553Not applicable1 country
- Henagliflozin's Impact on Prediabetes RemissionNot yet recruitingNCT06448130Phase 41 country
- Glycaemic Index Determination in Oral Nutrition SupplementsRecruitingNCT06358716Not applicable1 country
- The Role of Oxytocin in Regulating Blood GlucoseRecruitingNCT06334172Not applicable1 country
- Efficacy and Safety of Android Artificial Pancreas System in Adult Patients With Type 1 Diabetes Mellitus in ChinaRecruitingNCT05726461Not applicable1 country
- The Relationship Between Diet and Glycemic Response and Inflammatory Markers in Children With Cystic FibrosisRecruitingNCT057484441 country
- Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes MellitusRecruitingNCT05779644Not applicable1 country
- OsteoPreP: Food Supplements for Postmenopausal Bone HealthCompletedNCT05348694Phase 41 country
- Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational DiabetesCompletedNCT06535789Phase 2/31 country
- Food Orders on Blood Glucose and Fuel Use at RestCompletedNCT06763562Not applicable1 country
- Day and Night Closed-loop in Young People With Type 1 DiabetesCompletedNCT02925299Not applicable2 countries
- Glucose Variability and Cognition in PrediabetesCompletedNCT042016001 country
- A Study of Adeno-Associated Virus Serotype 8-Mediated Gene Transfer of Glucose-6-Phosphatase in Patients With Glycogen Storage Disease Type Ia (GSDIa)CompletedNCT05139316Phase 39 countries
- A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)Active, not recruitingNCT07400653Phase 311 countries
- Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult CareActive, not recruitingNCT05910840Not applicable1 country
- Group Education Trial to Improve Transition for Parents of Adolescents With T1DCompletedNCT05445284Not applicable1 country
- Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)Active, not recruitingNCT06260722Phase 35 countries
- The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune ResponseCompletedNCT05558488Not applicable1 country
- Effect of NMN Supplementation on Organ System BiologyCompletedNCT04571008Not applicable1 country