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Amyloidosis clinical trials

The registry lists 290 studies for Amyloidosis across more than 10 countries. 92 are recruiting or about to start. 145 of them are mainly about Amyloidosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 7 narrower conditions too, such as Immunoglobulin Light-chain Amyloidosis: 689 studies, 228 open.

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
131
Recruiting
70
Not yet recruiting
18
Status unknown
17
Terminated
17
Active, not recruiting
15

Phase

Phase 2
82
Phase 1
54
Phase 3
43
Phase 4
5
Early Phase 1
5

Where

United States
141
France
56
Italy
52
United Kingdom
49
Spain
48
Germany
44

Who runs them

Alnylam Pharmaceuticals (22) · Mayo Clinic (11) · GlaxoSmithKline (9) · Eidos Therapeutics, a BridgeBio company (8) · Fondazione IRCCS Policlinico San Matteo di Pavia (8) · Brigham and Women's Hospital (8) · Pfizer (8) · Ionis Pharmaceuticals, Inc. (8)

What is being tested here

Drugs under test in Amyloidosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Acoramidis358
Etentamig212
Autologous Bispecific BCMA/CD19-targeted CAR-T Cells GC012F202
Belantamab mafodotin202
Nucresiran222
Dexamethasone1117
Daratumumab117
Bortezomib106
Eplontersen134
Cyclophosphamide104

Drug classes tested here Alkylating agents 1 open · Proteasome inhibitors 1 open

Coming up

16phase 3 studies under way
28studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 70 Amyloidosis studies recruiting now, 43 (61%) set no upper age limit and 3 (4%) stop at 75 or younger. 7 (10%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 9 (13%) take healthy volunteers.

Recruiting studies that take each age, of 70
AgeWomenMen
107 (10%)6 (9%)
1861 (87%)60 (86%)
3064 (91%)63 (90%)
4066 (94%)65 (93%)
5067 (96%)66 (94%)
6570 (100%)69 (99%)
7569 (99%)68 (97%)
8556 (80%)55 (79%)

Across all 290 studies, recruiting or not: 14% stop at 75 or younger and 7% at 65; 7% take children; <1% are for women only and <1% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Amyloidosis studies take

Of 25 phase 3 interventional studies under Amyloidosis, half reached primary completion within 53 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 131 mo6–58 · 18 studies——
Phase 247 mo33–64 · 24 studies——
Phase 353 mo40–74 · 25 studies——
Interventional, no phase35 mo25–75 · 26 studies——
Observational97 mo29–183 · 52 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Results posted1

Stopped1

Newly registered2

Studies

Recruiting first, then most recently updated. Showing 50 of 290. Browse all 290 → or search them.