Bone Diseases, Metabolic clinical trials
The registry lists 661 studies for Bone Diseases, Metabolic across more than 10 countries. 93 are recruiting or about to start. 253 of them are mainly about Bone Diseases, Metabolic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 8 narrower conditions too, such as Osteoporosis: 2,371 studies, 325 open.
ClinicalTrials.gov finds 3,288 studies for Bone Diseases, Metabolic. How that becomes 661 here
This page counts the studies the registry files under Bone Diseases, Metabolic, and those it files under no condition that list Bone Diseases, Metabolicthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 3,288Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −1,662Filed under a narrower condition, counted on its own pageOsteoporosis 1,288 · Osteoporosis, Postmenopausal 197 · Chronic Kidney Disease-Mineral and Bone Disorder 65 · Familial Hypophosphatemic Rickets 48 · Rickets 28 · Pseudohypoparathyroidism 22 · 2 more
- −965Match it another way2 name it in the title, 1 in a keyword, and 962 by a synonym or other text the search reads.
- 661The count on this page
Get an email when these change. Save the Bone Diseases, Metabolic studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
Amgen (23) · Cairo University (18) · Massachusetts General Hospital (12) · Novartis Pharmaceuticals (10) · Columbia University (9) · Mansoura University (8) · Menoufia University (8) · University of Nebraska (7)
What is being tested here
Drugs under test in Bone Diseases, Metabolic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cholecalciferol | 2 | 1 | 10 |
| Eldecalcitol | 2 | 0 | 2 |
| Zoledronic Acid | 1 | 9 | 25 |
| Denosumab | 1 | 14 | 25 |
| Risedronic Acid | 1 | 6 | 17 |
| Vitamin D | 1 | 1 | 12 |
| Melatonin | 1 | 0 | 3 |
| Prune | 1 | 0 | 3 |
| Ibandronic Acid | 1 | 1 | 3 |
| Everolimus | 1 | 0 | 2 |
Drug classes tested here Integrase inhibitors 5 · Estrogens 4 · Statins 3 · DPP-4 inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026A Study Evaluating the Performance of Using AI Software and Chest X-rays to Screen for Osteoporosis as Compared to Standard DXA Scans in Patients 50 Years and Older · Promedius Inc
- Dec 2026AI-Supported Mobile High-Impact and Strengthening Exercise Program in Postmenopausal Women With Low Bone Density · Istanbul University
- Dec 2026Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor · University of Alabama at Birmingham
- Dec 2026Minimally Invasive Sinus Lift Through the Interradicular Septum · Universidad de Murcia
- Dec 2026Bone and Muscle Oxygenation in Military Test Pilots · Emine Merve Ersever
- Dec 2026The Use of Bio-Oss Collagen for Sinus Augmentation Using the Transcrestal Approach. · Rambam Health Care Campus
- Dec 2026Peripheral Mononuclear Cells to Screen, Monitor and Stratify the Population at Risk of Osteoporosis and Fractures · Istituto Ortopedico Rizzoli
- Dec 2026Physical Activity Guarantees Bone Density. · Poznan University of Physical Education
- Dec 2026Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Dec 2026Exosome microRNAs as Potential Biomarkers of Metabolic Bone Disease of Prematurity · Hunan Children's Hospital
Who these studies take
Of the 63 Bone Diseases, Metabolic studies recruiting now, 27 (43%) set no upper age limit and 28 (44%) stop at 75 or younger. 12 (19%) take children under 18. 12 (19%) are for women only and 1 (2%) for men only; 22 (35%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 10 (16%) | 8 (13%) |
| 18 | 38 (60%) | 33 (52%) |
| 30 | 40 (63%) | 35 (56%) |
| 40 | 43 (68%) | 40 (63%) |
| 50 | 49 (78%) | 42 (67%) |
| 65 | 47 (75%) | 40 (63%) |
| 75 | 36 (57%) | 31 (49%) |
| 85 | 33 (52%) | 29 (46%) |
Across all 661 studies, recruiting or not: 43% stop at 75 or younger and 29% at 65; 18% take children; 35% are for women only and 5% for men only; 41% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Bone Diseases, Metabolic studies take
Of 30 phase 4 interventional studies under Bone Diseases, Metabolic, half reached primary completion within 47 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 12 mo12–37 · 13 studies | — | — |
| Phase 2 | 31 mo23–34 · 19 studies | — | — |
| Phase 3 | 40 mo21–57 · 26 studies | — | — |
| Phase 4 | 47 mo25–64 · 30 studies | — | — |
| Interventional, no phase | 22 mo10–38 · 177 studies | — | 22 mo10–38 · 161 studies |
| Observational | 60 mo19–… · 52 studies | — | 60 mo19–… · 51 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Results posted1
- Melatonin and Osteogenic Loading on OsteopeniaOct 22, 2026NCT04233112
Stopped1
- Retrospective Observational Study of Implant-supported Restorations With Dental Implants.TerminatedOct 20, 2026NCT06154057
Newly registered3
- Melatonin in Posterior Mandible Extraction SocketNov 6, 2026NCT07921355
- AI-Supported Mobile High-Impact and Strengthening Exercise Program in Postmenopausal Women With Low Bone DensityNov 5, 2026NCT07918716
- Exercise and Fall Prevention for Fracture ReductionOct 27, 2026NCT07897929
Studies
Recruiting first, then most recently updated. Showing 50 of 661. Browse all 661 → or search them.
- Clinical and Molecular Characteristics of Primary Aldosteronism in BlacksRecruitingNCT033742151 country
- Melatonin in Posterior Mandible Extraction SocketNot yet recruitingNCT07921355Phase 2
- Exercise and Fall Prevention for Fracture ReductionNot yet recruitingNCT07897929Not applicable1 country
- Veverimer to Decrease Net Acid Excretion and Bone Resorption in Adults With OsteopeniaRecruitingNCT07473713Phase 11 country
- A Study Evaluating the Performance of Using AI Software and Chest X-rays to Screen for Osteoporosis as Compared to Standard DXA Scans in Patients 50 Years and OlderRecruitingNCT074217132 countries
- Evaluation of Children With Endocrine and Metabolic-Related ConditionsRecruitingNCT027699751 country
- Access to Probing and Peri-implant DiseasesRecruitingNCT075574591 country
- Time-Restricted Eating and Exercise for Bone HealthNot yet recruitingNCT07824375Not applicable1 country
- Comparison of Induced Membrane Technique With Vascularized Fibula Flap for Pediatric Limb ReconstructionNot yet recruitingNCT07825532
- Bone and Muscle Oxygenation in Military Test PilotsNot yet recruitingNCT07787143Not applicable
- The Comparison of Ibandronate and Zoledronic Acid After Denosumab DiscontinuationRecruitingNCT07406685Phase 41 country
- Calcium-Rich Food Versus Calcium Carbonate for Bone HealthNot yet recruitingNCT07763509Not applicable1 country
- High-Intensity Laser Therapy and Physiotherapy for Bone Health in Postmenopausal Women: A Randomized TrialNot yet recruitingNCT07734922Not applicable1 country
- Clinical Outcomes Study of the Nexel Total ElbowRecruitingNCT02469662Not applicable8 countries
- Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal WomenRecruitingNCT06184646Not applicable1 country
- Functional Muscle-Bone Incongruity Index (FKUI): A Prospective Observational StudyRecruitingNCT076770331 country
- Influence of Acetal Resin Versus Nylon Elastic Cap on Crestal Bone Loss in Mandibular Implant-Supported OverdentureNot yet recruitingNCT07666763Not applicable
- Bone, Exercise, Alendronate, and Caloric RestrictionRecruitingNCT05764733Phase 41 country
- Peripheral Mononuclear Cells to Screen, Monitor and Stratify the Population at Risk of Osteoporosis and FracturesRecruitingNCT065511551 country
- Effective Dosing of Burosumab in XLHRecruitingNCT071835791 country
- Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)RecruitingNCT070835571 country
- Food Trial Evaluating Fecal Abundance of SBD111 With Once-Daily Versus Twice-Daily Administration in Healthy AdultsNot yet recruitingNCT07538167Not applicable
- Evaluation of the Safety, Feasibility, and Early Clinical Outcomes of Patient-Specific Bone Defect Implants Fabricated From Titanium Alloy (Ti-6Al-4V) Using 3D Printing TechnologyNot yet recruitingNCT07540156Not applicable1 country
- Serum Myostatin and Irisin Levels in Postmenopausal Women: Association With Bone Mineral Density and Muscle StrengthNot yet recruitingNCT07519551
- Resistance Training and Rapamycin to Enhance Bone Formation in Postmenopausal WomenRecruitingNCT07191353Phase 21 country
- Shoulder Dislocation: Assessment of Lesions, Trajectories and Outcomes (SALTO)Not yet recruitingNCT074864401 country
- Comparison of Bone Microarchitecture Analysed by HRpQCT and pQCT in Pathologies With Bone Loss and/or Muscle LossRecruitingNCT06541548Not applicable1 country
- Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)RecruitingNCT065276641 country
- Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric SurgeryRecruitingNCT04922333Phase 31 country
- Minimally Invasive Sinus Lift Through the Interradicular SeptumRecruitingNCT05237570Not applicable1 country
- REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)RecruitingNCT07412782Not applicable1 country
- Therapeutic Wavelength Nanotechnology Devices in Alveolar PreservationNot yet recruitingNCT07371130Not applicable
- All-on-X Stackable Guides for Maxillary Terminal DentitionRecruitingNCT073536191 country
- Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth FactorRecruitingNCT04954664Not applicable1 country
- Estrogen Supplementation and Bone Health in Women With CFRecruitingNCT05704036Phase 41 country
- Lutein, Zeaxathin, and Fish Oil SupplementationRecruitingNCT06489873Not applicable1 country
- Prospective Outcomes of Guided Equator OverdenturesRecruitingNCT071969431 country
- Profylactic Treatment for Patients in Risk OsteoporosisRecruitingNCT05787808Not applicable1 country
- Crestal Bone Response to Narrow vs. Regular Tie-Base in Subcrestal ImplantsNot yet recruitingNCT07196228Not applicable
- Zoledronic Acid for the Prevention of TDF-sparing ART-induced Bone Mass Density Loss in Treatment-naive HIV Positive IndividualsRecruitingNCT06762730Phase 41 country
- Metabolic Profile of Bone in Professional AthletesRecruitingNCT033869811 country
- Cardiovascular-Kidney-Metabolic Syndrome in Shanghai ZicitizensRecruitingNCT070431661 country
- Prosthetic Modality and MBLRecruitingNCT07156110Not applicable1 country
- An International, Multicenter, Prospective Registry on Post-traumatic Long Bones DefectsRecruitingNCT0411299214 countries
- Mandibular Overdentures Retained by Four Locator Attachments Versus Four-Implant Bar AttachmentsRecruitingNCT070938531 country
- Induced Membrane Properties in Children and AdultsRecruitingNCT04246944Not applicable1 country
- Study on Safety and Performance of AdvanCore Bone Void FillerRecruitingNCT06736457Not applicable1 country
- Brief Title: The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke.Not yet recruitingNCT06961825Not applicable1 country
- Osteogenic Action of a Medical Device Based on Beta-tricalcium Phosphate (BTCP)Not yet recruitingNCT06935747Phase 41 country
- Biomechanical Effects of Digitally Constructed Subperiosteal ImplantsRecruitingNCT063620571 country