Hypercapnia clinical trials
The registry lists 185 studies for Hypercapnia across more than 10 countries. 34 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-14.
Status
- Completed
- 97
- Status unknown
- 30
- Recruiting
- 21
- Terminated
- 15
- Not yet recruiting
- 12
- Withdrawn
- 6
Phase
- Phase 3
- 8
- Phase 1
- 7
- Phase 4
- 5
- Phase 2
- 4
Where
- United States
- 35
- France
- 23
- Germany
- 15
- Italy
- 13
- Spain
- 12
- China
- 10
Who runs them
Assiut University (5) · Czech Technical University in Prague (5) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (5) · Centro Universitario La Salle (4) · University Hospital, Rouen (4) · Schön Klinik Berchtesgadener Land (3) · Assistance Publique - Hôpitaux de Paris (3) · Guy's and St Thomas' NHS Foundation Trust (3)
Studies
Recruiting first, then most recently updated. Showing 50 of 185 — search for more.
- Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.RecruitingNCT07432191Not applicable1 country
- ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their CaregiversNot yet recruitingNCT07778004Not applicable1 country
- Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory SupportNot yet recruitingNCT07751003Not applicable1 country
- Timing of Opioid Administration and Postoperative Respiratory Depression.RecruitingNCT072273891 country
- Effectiveness and Efficiency of Home Telemonitoring and Non-invasive Ventilation in Patients With COPD and Hypercapnia (EVALECO)Not yet recruitingNCT076796461 country
- End Tidal Carbon Dioxide Concentration and Depth of Anesthesia in ChildrenRecruitingNCT06303518Not applicable1 country
- Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord InjuryRecruitingNCT05536076Not applicable1 country
- How Nocturnal Hypoventilation Predicts Long-term Response to Non-invasive Ventilation in Hypercapnic COPD PatientsRecruitingNCT074141081 country
- The Effect of Respiratory Challenge on the BOLD SignalEnrolling by invitationNCT04258774Not applicable1 country
- Intraperitoneal Gas Drainage to Reduce Postoperative Shoulder Pain After Gynecologic Laparoscopy .Not yet recruitingNCT07262749Not applicable
- Oxygen Toxicity: Mechanisms in HumansRecruitingNCT05761756Not applicable1 country
- Impact of Home Non Invasive Ventilation in Patients With Chronic Obstructive Pulmonary Disease Discharged From Assiut University HospitalNot yet recruitingNCT07198880Not applicable
- DUET Versus Standard Interface for Hypercapnic COPD PatientsRecruitingNCT05829083Not applicable1 country
- Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO ApplicationRecruitingNCT070999631 country
- HVNI vs NIPPV in Type 2 Respiratory FailureNot yet recruitingNCT07065656Not applicable
- Respiratory Strategies in COPD Patients With Persistent Hypercapnia Following ExacerbationRecruitingNCT07065799Not applicable1 country
- Improving Non-invasive VentilationRecruitingNCT015719861 country
- The Simplify ProjectRecruitingNCT050118771 country
- High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary DiseaseRecruitingNCT03033251Not applicable1 country
- To Assess the Types of Mechanical Ventilation in Enabling Therapeutic Bronchofiberoscopy in Patients With Decompensated Respiratory Acidosis (Complete Respiratory Failure).Not yet recruitingNCT06970041Not applicable
- Survey on NIV Settings in the Intensive Care Unit for Acute Exacerbation of COPDNot yet recruitingNCT06888180
- Home High-Flow Nasal Cannula vs. Noninvasive Ventilation for Stable Chronic Respiratory FailureNot yet recruitingNCT06872801Not applicable1 country
- Effects of Walking Apnea At Low Lung Volume on HypoalgesiaRecruitingNCT06638515Not applicable1 country
- Effects of Walking Apnea At High Lung Volume on HypoalgesiaRecruitingNCT06638528Not applicable1 country
- Optimising Ventilatory Strategies by Using Positive Respiratory Integer MeasurementsNot yet recruitingNCT062984351 country
- Treatment of Acute Hypercapnic Respiratory Failure With OptiflowTM or Optiflow+DuetTM Nasal Cannula in COPD-patientsNot yet recruitingNCT06257667Not applicable
- Comfort of Patients Under Non Invasive Ventilation According to the MaskNot yet recruitingNCT062121801 country
- Effects of Walking Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory FunctionRecruitingNCT06158282Phase 31 country
- Effects of Walking Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory FunctionRecruitingNCT06158295Phase 31 country
- Effects of Static Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory FunctionRecruitingNCT06158256Phase 31 country
- Effects of Static Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory FunctionRecruitingNCT06150677Phase 31 country
- Novel ECCO2R Device for Hypercapnic Respiratory FailureRecruitingNCT053165321 country
- NIV for Hypercapnic Respiratory Failure: AVAPS vs S/T BIPAPRecruitingNCT06047405Not applicable1 country
- Home Non Invasive Ventilation for COPD PatientsRecruitingNCT03221101Not applicable1 country
- Combination of High-flow Nasal Oxygen (Optiflow) and Vibrating Membrane Nebuliser (Aerogen) in the Pre-hospital Setting - Before/After StudyWithdrawnNCT077919921 country
- Post-Extubation High-Flow Nasal Cannula Versus Non-Invasive Ventilation in Type II Respiratory FailureCompletedNCT06918288Not applicable1 country
- Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity HypoventilationTerminatedNCT04131660Not applicable1 country
- Effect of FFP2 Masks on Peripheral Oxygen Saturation and Pulse Rate During the COVID-19 PandemicCompletedNCT051886511 country
- The Effect of Hypercapnia on Physiological Parameters During Short-term BreathingCompletedNCT05441007Not applicable1 country
- Variability of SpO2 Measurements Depending on the Choice of Finger for Sensor PlacementCompletedNCT04771663Not applicable1 country
- Contribution of Nasal High Flow in Pneumology Assessed in Acid-Free Hypercapnic Acute Respiratory FailureTerminatedNCT06008587Not applicable2 countries
- Evaluation of Accuracy and Precision of a New Arterial Blood Gas Analysis System Blood in Comparison With the Reference StandardTerminatedNCT02801162Not applicable1 country
- The Efficacy of Laryngeal Mask Airway Gastro (LMA® Gastro™) in Preventing Hypercarbia in ERCP PatientsCompletedNCT07182786Not applicable1 country
- Hypercapnic Acute Respiratory Failure in the ICU : the YETI StudyCompletedNCT043043391 country
- Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord InjuryTerminatedNCT06101199Not applicable1 country
- Early Non-invasive Ventilation Outside the Intensive Care UnitCompletedNCT01572337Phase 43 countries
- Effect of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on VentilationCompletedNCT05470465Phase 11 country
- Listen to a Audio BookCompletedNCT06944093Not applicable1 country
- Safety and Efficacy Evaluation of CO2 Removal in Combination With Continuous Veno-Venous Hemodialysis/Hemodiafiltration TherapyCompletedNCT04871893Not applicable1 country
- Influence of Caffeine on Psychomotor Vigilance and Carbon Dioxide Tolerance During Graded HypercapniaCompletedNCT06636825Not applicable1 country