An interventional study of Breathing a mixture of O2, N2 and CO2 and monitoring SpO2 on each finger in Hypoxia and Hypercapnia, sponsored by Czech Technical University in Prague. Completed at 1 site in Czechia. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-11.
Sponsored by Czech Technical University in Prague · Not applicable, Interventional, and Basic science
The aim of the project is to experimentally determine the effect of the choice of finger for the placement of a pulse oximeter sensor on the results of measuring peripheral blood oxygen saturation (SpO2) in a healthy person with short-term hypoxia and hypercapnia.
The aim of the project is to experimentally determine the effect of the choice of finger for the placement of a pulse oximeter sensor on the results of measuring peripheral blood oxygen saturation (SpO2) in a healthy person with short-term hypoxia and hypercapnia. This is an intervention prospective study that will take place at the Faculty of Biomedical Engineering, especially on FBMI students. The experiment consists of two phases, in which in the first phase, the volunteers will inhale the hypoxic mixture for five minutes after the stabilization phase. In the second phase, volunteers inhale a hypoxic and hypercapnic mixture. During the experiment, non-invasive SpO2 measurements will be performed continuously on individual fingers of both volunteer hands.
1,076 studies on the registry are indexed under Hypoxia; 213 are open to participants now.
This study's enrollment of 24 is below the median of 45 across 769 interventional studies indexed under Hypoxia.
Browse Hypoxia studies →Czech Technical University in Prague is the lead sponsor of 36 studies on the registry; 6 are open to participants now.
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In this phase, participants inhale the hypoxic mixture for five minutes.
Other: Breathing a mixture of O2, N2 and CO2 and monitoring SpO2 on each finger
In this phase, participants inhale the hypoxic and hypercapnic mixture for five minutes.
Other: Breathing a mixture of O2, N2 and CO2 and monitoring SpO2 on each finger
The experiment consists of two separate phases. In one phase, the volunteers inhale one of the mixtures for five minutes. After enough time of recovery, the volunteers undergo the other phase in which they inhale the other mixture of gases. Both phases of the measurement will begin with a two-minute stabilization phase, during which the physiological values of the volunteer will be checked. During the experiment, non-invasive SpO2 measurements will be performed continuously on the individual fingers of both volunteer hands throughout the experiment.
Does it depend on which finger is the sensor placed for SpO2 values?
The experiment can help determine if it depends on which finger the finger sensor will be placed to measure SpO2. Appropriate finger selection for SpO2 measurements could help to better interpret the measured values and possibly increase the success in diagnosing health events.
Time frame: Up to 12 weeks
Plan to share: No
Ran from Nov 2020 to primary completion in Feb 2021, 3 months.
Of 321 non-industry interventional studies with no phase under Hypoxia, half reached primary completion within 12 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 27. This study's 3 months is below that.
Counting every sponsor, half of 351 studies reached it within 12 months; a quarter within 3 and three quarters within 27.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.
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Czech Technical University in Prague