Heroin Dependence clinical trials
The registry lists 90 studies for Heroin Dependence across more than 10 countries. 1 are recruiting or about to start. 71 of them are mainly about Heroin Dependence (how this is decided). Per ClinicalTrials.gov, last updated 2025-10-27.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Institute on Drug Abuse (NIDA) (13) · New York State Psychiatric Institute (10) · Wayne State University (7) · Johns Hopkins University (6) · University of Colorado, Denver (6) · National Health Research Institutes, Taiwan (4) · Universiti Sains Malaysia (3) · Friends Research Institute, Inc. (3)
What is being tested here
Drugs under test in Heroin Dependence studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Buprenorphine | 0 | 7 | 12 |
| Naltrexone | 0 | 3 | 9 |
| Naloxone | 0 | 4 | 6 |
| Methadone | 0 | 0 | 2 |
| Cannabidiol | 0 | 0 | 1 |
| Memantine | 0 | 1 | 1 |
| Clonidine | 0 | 0 | 1 |
| Vivitrol | 0 | 1 | 1 |
| Methadyl Acetate | 0 | 0 | 1 |
| Lofexidine | 0 | 0 | 1 |
Drug classes tested here Opioids 17 · Opioid antagonists 15
Who these studies take
Of the 1 Heroin Dependence studies recruiting now, 0 (0%) set no upper age limit and 1 (100%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 0 (0%) | 0 (0%) |
| 30 | 1 (100%) | 1 (100%) |
| 40 | 1 (100%) | 1 (100%) |
| 50 | 1 (100%) | 1 (100%) |
| 65 | 1 (100%) | 1 (100%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 90 studies, recruiting or not: 74% stop at 75 or younger and 72% at 65; 2% take children; 1% are for women only and 10% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 90. Browse all 90 → or search them.
- Light Needle for Opioid Use DisorderRecruitingNCT05341219Not applicable1 country
- Neuroimaging and CBD for Opioid Use DisorderCompletedNCT04567784Phase 21 country
- Combining Neuro-Imaging and Non-Invasive Brain Stimulation for Clinical Intervention in Opioid Use DisorderTerminatedNCT04495673Not applicable1 country
- Change the Cycle: An RCT to Prevent Injection InitiationCompletedNCT02774954Not applicable1 country
- Biomarkers of Injectable Extended Release Naltrexone TreatmentCompletedNCT02324725Phase 41 country
- Buprenorphine Stabilization and Induction Onto Vivitrol for Heroin-dependent IndividualsTerminatedNCT03711318Phase 31 country
- Repetitive Transcranial Magnetic Stimulation to Reduce Heroin CravingsCompletedNCT05074524Not applicable1 country
- Youth Opioid Recovery Support: Improving Care SystemsCompletedNCT04015115Not applicable1 country
- The Effect of Self-Forgiveness on Self-Stigma in Addiction.CompletedNCT03971097Not applicable1 country
- Extended-Release Naltrexone Opioid Treatment at Jail Re-EntryCompletedNCT01999946Phase 41 country
- Efficacy of Repetitive Transcranial Magnetic Stimulation and Cognitive Behavioral Therapy on Heroin DependenceStatus unknownNCT03922659Not applicable1 country
- PET/MRI Study on the Neurological Mechanism of rTMS Treatment for Heroin AddictionStatus unknownNCT04086459Not applicable1 country
- Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid AbstinenceCompletedNCT03015246Phase 1/21 country
- Repetitive Transcranial Magnetic Stimulation in Patients With Opioid Use DisordersStatus unknownNCT03229642Not applicable1 country
- Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1CompletedNCT00023283Phase 21 country
- Study of Computer-Based Treatment for Drug DependenceCompletedNCT01315184Phase 21 country
- Laser Meridian Massage in Heroin AddictsStatus unknownNCT04003077Not applicable1 country
- Methadone Induced Memory Retrieval-extinction Procedure in Heroin AddictsCompletedNCT04133974Not applicable
- Buprenorphine Maintenance Treatment of Opioid Dependence in Primary Care: A Randomized Clinical TrialCompletedNCT00684554Phase 2/31 country
- Study of Buprenorphine Maintenance Treatment for Opioid Dependence in Primary CareCompletedNCT004710421 country
- An Observational Study of Environmental and SocioEconomic Factors in Opioid RecoveryCompletedNCT036048611 country
- Addiction Treatment in Russia: Oral vs. Naltrexone ImplantCompletedNCT00218426Phase 2/32 countries
- Buprenorphine for PrisonersCompletedNCT00574067Phase 31 country
- University of Houston Drug Abuse Research Development Program IIStatus unknownNCT03557632Not applicable1 country
- Memantine as a Supplement to Naltrexone in Treating Heroin DependenceCompletedNCT00476242Phase 2/31 country
- Studies of Opioid Seeking Behavior: Yohimbine and Hydrocortisone EffectsCompletedNCT015369251 country
- Effect of Clonidine on Responses to Imagery ScriptsCompletedNCT00318760Phase 11 country
- Skills Based Counseling for Adherence and Depression in HIV+ Methadone Patients - 1CompletedNCT00218634Not applicable1 country
- The Therapeutic Workplace Initiation StudyCompletedNCT00249470Not applicable1 country
- Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2CompletedNCT00249457Not applicable1 country
- Employment-based Reinforcement of Naltrexone Ingestion and AbstinenceCompletedNCT00149669Not applicable1 country
- Reinforcing Effects of Intranasal (IN) Buprenorphine Versus Buprenorphine/NaloxoneCompletedNCT01760473Phase 31 country
- Behavioral Naltrexone Therapy for Promoting Adherence to Oral Naltrexone vs Extended Release Injectable Depot NaltrexoneCompletedNCT00577408Phase 31 country
- Pioglitazone for Heroin and for Nicotine DependenceTerminatedNCT01395797Phase 1/21 country
- A Laboratory Model for Heroin Abuse Medications - 8CompletedNCT00000273Phase 21 country
- Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-3 - 6WithdrawnNCT00000331Phase 21 country
- Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4WithdrawnNCT00000329Phase 21 country
- Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment III) - 3WithdrawnNCT00000328Phase 21 country
- Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment I(2) - 2WithdrawnNCT00000327Phase 21 country
- Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-2 - 5WithdrawnNCT00000330Phase 21 country
- Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment 1 - 1WithdrawnNCT00000326Phase 21 country
- Economic Evaluation Comparing CCT With MMT in Hai Phong City, VietnamCompletedNCT030713151 country
- ALK21-013: Efficacy and Safety of Medisorb® Naltrexone (VIVITROL®) in Adults With Opioid DependenceCompletedNCT00678418Phase 31 country
- Buprenorphine and Naloxone for the Treatment of Opiate Dependence - 1CompletedNCT00015171Phase 31 country
- Bridging Active Heroin Users to Hepatitis C Treatment Using Buprenorphine - 1CompletedNCT00249574Not applicable1 country
- Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing RegimensCompletedNCT00218127Phase 21 country
- Treatment Efficacy for Drug Abuse and AIDS Prevention - 2CompletedNCT00000211Phase 21 country
- Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent IndividualsCompletedNCT002183091 country
- The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1CompletedNCT00158288Phase 21 country
- Buprenorphine and Naloxone Combination Study - 10CompletedNCT00015288Phase 11 country