An interventional study of Contingency management in Behavior, Addictive, Cocaine Abuse and Cocaine Dependence, sponsored by Johns Hopkins University. Completed at 1 site in United States. Open to female participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2017-10-30.
Sponsored by Johns Hopkins University · Not applicable, Interventional, and Treatment
The purpose of this study is to determine whether long-term exposure to the Therapeutic Workplace intervention could sustain drug abstinence over an extended period of time in heroin- and cocaine-dependent, unemployed, treatment-resistant young mothers.
The current study is a continuation of the research into the development and evaluation of a novel treatment designed to address the chronic, persistent nature of drug addiction. This treatment, called the Therapeutic Workplace, integrates abstinence reinforcement contingencies of proven efficacy into a model supported work program. Participants were paid to work or to train in the Therapeutic Workplace but had to provide drug-free urine samples to gain daily access. Forty participants were randomly assigned to a Therapeutic Workplace or usual care control group. Therapeutic Workplace participants could work for about 5 years. This study reports the effects of the intervention over a follow-up period of 8 years after treatment initiation.
416 studies on the registry are indexed under Cocaine-Related Disorders; 12 are open to participants now.
This study's enrollment of 40 is below the median of 60 across 313 interventional studies indexed under Cocaine-Related Disorders.
Browse Cocaine-Related Disorders studies →Johns Hopkins University is the lead sponsor of 1,815 studies on the registry; 315 are open to participants now.
Of its 208 completed or terminated interventional studies of FDA-regulated products, 144 (69%) have results posted.
Compared within Cocaine-Related Disorders, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Behavior, Addictive. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Contingency management. Invited to work in the Therapeutic Workplace. Completed monthly assessments.
Behavioral: Contingency management
No intervention. Not invited to work int the Therapeutic Workplace. Completed monthly assessments.
Invited to attend the Therapeutic Workplace 3 hr per day, Monday through Friday. Each day when a participant reported to the workplace, she was required to provide a urine sample. If the sample tested negative for opiates and cocaine, she was allowed to work that day. Participants who gained entrance to the workplace participated in basic skills education and job skills training throughout each 3-hr work shift.
Percentage of urine samples at the assessments that were negative for cocaine
(total number of monthly urine samples negative for cocaine/total number of possible urine samples) x 100
Time frame: every 30 days throughout fourth year
Percentage of urine samples at the assessments that were negative for opiates
(total number of monthly urine samples negative for opiates/total number of possible urine samples) x 100
Time frame: every 30 days throughout fourth year
Percentage of urine samples at the assessments that were negative for cocaine and opiates
(total number of monthly urine samples negative for cocaine and opiates/total number of possible urine samples) x 100
Time frame: every 30 days throughout fourth year
HIV risk behaviors
Time frame: every 30 days throughout fourth year
Percentage of participants employed each month
Time frame: every 30 days throughout fourth year
Number of days employed each month
Time frame: every 30 days throughout fourth year
Percentage of participants to self-report abstinence at all time points
Time frame: every 30 days throughout fourth year
Plan to share: No — The data for this study have been published in a peer-reviewed journal.
This study is completed, as verified in Oct 2017. You cannot join it, but the record below documents what was studied.
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