Gastrointestinal Diseases clinical trials
The registry lists 548 studies for Gastrointestinal Diseases across more than 10 countries. 101 are recruiting or about to start. 210 of them are mainly about Gastrointestinal Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 101 narrower conditions too, such as Colorectal Neoplasms: 28,303 studies, 6,928 open.
ClinicalTrials.gov finds 47,358 studies for Gastrointestinal Diseases. How that becomes 547 here
This page counts the studies the registry files under Gastrointestinal Diseases, and those it files under no condition that list Gastrointestinal Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 47,358Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −25,711Filed under a narrower condition, counted on its own pageColorectal Neoplasms 6,086 · Stomach Neoplasms 2,802 · Crohn Disease 1,891 · Colonic Neoplasms 1,395 · Rectal Neoplasms 1,288 · Esophageal Neoplasms 1,213 · 91 more
- −27List Gastrointestinal Diseases as a condition, but the registry did not file them under itMost often written as “Cystic Fibrosis Gastrointestinal Disease” (6), “H.Pylori Gastrointestinal Disease” (3), and “Gastrointestinal Disorder Postoperative” (2). The registry filed 17 of them under no condition at all, and the others under other conditions only, most often Cystic Fibrosis (6) and Food Hypersensitivity (1).
- −21,073Match it another way25 name it in the title, 5 in a keyword, and 21,043 by a synonym or other text the search reads.
- 547The count on this page
Get an email when these change. Save the Gastrointestinal Diseases studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Karolinska Institutet (10) · National Center for Research Resources (NCRR) (9) · Boston Children's Hospital (7) · AstraZeneca (7) · Massachusetts General Hospital (6) · Mayo Clinic (6) · Renmin Hospital of Wuhan University (6) · Exact Sciences Corporation (6)
What is being tested here
Drugs under test in Gastrointestinal Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Immune checkpoint inhibitors 3 open · Tyrosine kinase inhibitors (TKIs) 2 open · Corticosteroids 1 open · Antimetabolites 8 · Proton pump inhibitors (PPIs) 8
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Iltamiocel Compared to Placebo for Chronic Fecal Incontinence in Females With Obstetric Injury · Phase 3 · Cook MyoSite
- Nov 2026Butyrate Supplementation in Children With Autism Spectrum Disorder (ASD) and Functional Gastrointestinal Disorders · Istituto Superiore di Sanità
- Nov 2026Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patients · Jiangxi Provincial Cancer Hospital
- Dec 2026NLP to Aid in the Evaluation and Diagnosis of FGIDs · Massachusetts General Hospital
- Dec 2026Adding a Gastrointestinal Subscore to SOFA2 for Mortality Risk Assessment in the ICU: The SOFA2-GIS Study · Ozkul Yilmaz Colak
- Dec 2026The Safety and Efficacy of Robotic Assisted Surgery Using Vessel Sealer Extend in Locally Advanced Gastric Cancer · The First Hospital of Jilin University
- Dec 2026Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered Neonates · Anabio R&D
- Dec 2026Enhanced Ward Rounds and Communication for Pre-procedural Anxiety in GI Endoscopy Patients · LanZhou University
- Dec 2026Exploring Novel Therapeutic Approaches for Disorders of Gut-Liver-Brain Interaction-H1/H2 · Buddhist Tzu Chi General Hospital
- Dec 2026Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome · Medical College of Wisconsin
Who these studies take
Of the 65 Gastrointestinal Diseases studies recruiting now, 30 (46%) set no upper age limit and 22 (34%) stop at 75 or younger. 18 (28%) take children under 18. 1 (2%) are for women only and 1 (2%) for men only; 20 (31%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 10 (15%) | 10 (15%) |
| 18 | 56 (86%) | 56 (86%) |
| 30 | 52 (80%) | 53 (82%) |
| 40 | 51 (78%) | 52 (80%) |
| 50 | 51 (78%) | 52 (80%) |
| 65 | 49 (75%) | 50 (77%) |
| 75 | 46 (71%) | 47 (72%) |
| 85 | 38 (58%) | 39 (60%) |
Across all 548 studies, recruiting or not: 45% stop at 75 or younger and 32% at 65; 29% take children; 2% are for women only and 1% for men only; 24% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Gastrointestinal Diseases studies take
Of 23 phase 2 interventional studies under Gastrointestinal Diseases, half reached primary completion within 31 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 31 mo21–46 · 23 studies | — | — |
| Phase 3 | 34 mo23–48 · 21 studies | — | — |
| Interventional, no phase | 24 mo10–45 · 149 studies | — | 26 mo11–46 · 127 studies |
| Observational | 65 mo24–155 · 65 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting3
- Rural Water Filtration and Health StudyNov 9, 2026NCT07818902
- A Sub Study to Investigate the Safety and Tolerability of Aletekitug in Participants With Moderate To Severe Ulcerative ColitisNov 5, 2026NCT07747480
- A Study to Investigate the Safety and Tolerability of Multiple Study Interventions in Participants With Moderate to Severe Ulcerative ColitisOct 28, 2026NCT07747467
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 548. Browse all 548 → or search them.
- Optical Imaging of Gastrointestinal Biopsy Samples and Their Correlation With HistologyEnrolling by invitationNCT04565704Not applicable1 country
- Rural Water Filtration and Health StudyRecruitingNCT07818902Not applicable1 country
- Study on the Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in the Treatment of Functional Gastrointestinal DisordersNot yet recruitingNCT07925424Not applicable
- A Sub Study to Investigate the Safety and Tolerability of Aletekitug in Participants With Moderate To Severe Ulcerative ColitisRecruitingNCT07747480Phase 11 country
- A Multilevel Approach to Connecting Underrepresented Populations to Clinical TrialsRecruitingNCT056554941 country
- Evaluation of Patients With Gastrointestinal DiseaseRecruitingNCT050413741 country
- A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in GermanyRecruitingNCT071023681 country
- Virtual Reality for Non-cardiac Chest PainRecruitingNCT06262126Not applicable1 country
- A Study to Investigate the Safety and Tolerability of Multiple Study Interventions in Participants With Moderate to Severe Ulcerative ColitisRecruitingNCT07747467Phase 11 country
- Foregut Leaks-Role of MicrobiomeRecruitingNCT07424469Not applicable1 country
- Psychological Prehabilitation for Complex Gastrointestinal SurgeryRecruitingNCT07865052Not applicable1 country
- Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal CancerRecruitingNCT07222800Phase 317 countries
- Subclinical Gastrointestinal Involvement in Juvenile Systemic Lupus ErythematosusNot yet recruitingNCT07858461
- Exploring Novel Therapeutic Approaches for Disorders of Gut-Liver-Brain Interaction-H1/H2RecruitingNCT07857941Phase 21 country
- Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBSRecruitingNCT07197944Phase 314 countries
- Mechanism of FODMAP Restriction on FGID PatientsRecruitingNCT07000227Not applicable1 country
- Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in ChildrenRecruitingNCT07222943Not applicable1 country
- Immune Responses to GlutenEnrolling by invitationNCT05209568Not applicable1 country
- Fecal Calprotectin in Pediatric Gastrointestinal DisordersNot yet recruitingNCT07807527
- Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal ResectionsRecruitingNCT07351071Not applicable1 country
- The Safety and Efficacy of Robotic Assisted Surgery Using Vessel Sealer Extend in Locally Advanced Gastric CancerRecruitingNCT068810431 country
- Effects of Goat Milk Formula on Gastrointestinal Comfort and Growth in InfantsNot yet recruitingNCT07778927Not applicable
- Understanding New Cachexia Subtypes Through Observational Epidemiological ResearchRecruitingNCT077763531 country
- Functional GI Disease RegistryEnrolling by invitationNCT052954461 country
- Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered NeonatesRecruitingNCT07320287Not applicable1 country
- Evaluation of the Effects of Colipral on Microbiota Gut Composition in Patients Presenting With Ulcerative Colitis During Remission Phase and Functional DisordersNot yet recruitingNCT07751081Not applicable1 country
- Effect of Virtual Reality Before Upper Gastrointestinal Endoscopy on Preprocedural Anxiety, Psychological Readiness, and Postprocedural SatisfactionNot yet recruitingNCT07745959Not applicable1 country
- Endoscopists' Perspectives on the Use of Single-Use Gastroscopes in Elective and Subacute Patients in the Endoscopy UnitRecruitingNCT07727226Not applicable1 country
- Efficacy and Mechanistic Evaluation of Hewei Anchang Formula for Overlapping Gastrointestinal Symptoms in Patients With Coexisting Functional Dyspepsia and Diarrhea-Predominant Irritable Bowel SyndromeNot yet recruitingNCT07715760Not applicable1 country
- Performance Characteristics and Technical Outcomes of Single-use Gastroscopes Used Bedside Versus Reusable Gastroscopes Used in the Endoscopy Unit Evaluated in Subacute PatientsRecruitingNCT06771102Not applicable1 country
- Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery.RecruitingNCT07483658Not applicable1 country
- Trans-nasal Endoscopy for Bariatric PatientsRecruitingNCT06200961Not applicable1 country
- Gastro-intestinal Biopotential Recorder by Means of Surface ELEctrodesRecruitingNCT06197334Not applicable1 country
- High Resolution Manometry After Partial Fundoplication for Gastro-oesophageal RefluxRecruitingNCT05132816Not applicable1 country
- Internet-delivered Psychological Treatment of Functional Gastrointestinal DisordersNot yet recruitingNCT07636122Not applicable
- Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC)RecruitingNCT06904872Phase 22 countries
- Functionally Enhanced Limosilactobacillus Reuteri Probiotic Preparation in Elderly Patients With Functional Bowel DisordersNot yet recruitingNCT07624656Not applicable
- A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsRecruitingNCT03093116Phase 1/219 countries
- Adding a Gastrointestinal Subscore to SOFA2 for Mortality Risk Assessment in the ICU: The SOFA2-GIS StudyNot yet recruitingNCT075862541 country
- Exclude or Expose in Irritable Bowel Syndrome: What Works for Whom and How?RecruitingNCT06940596Not applicable1 country
- NLP to Aid in the Evaluation and Diagnosis of FGIDsEnrolling by invitationNCT055010281 country
- Evaluation of Outcomes From Treatment of Benign or Malignant Gastrointestinal DiseasesEnrolling by invitationNCT051158771 country
- GpCRC Pediatric Gastroparesis Registry 2RecruitingNCT059813001 country
- Gastroparesis Registry 4RecruitingNCT058468021 country
- Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.RecruitingNCT06290258Phase 1/21 country
- Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation (The PREDICT Trial)Enrolling by invitationNCT033693531 country
- Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic DiseasesRecruitingNCT06529913Not applicable1 country
- Saudi Emergency Laparotomy AuditNot yet recruitingNCT074299291 country
- Elemental 028 Extra Case StudiesRecruitingNCT06877923Not applicable1 country
- Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos SyndromeRecruitingNCT05212129Not applicable1 country