Supplement
Probiotic clinical trials
Also written Bio 25.
- studies test it
- 436
- open now
- 79
- in phase 3
- 31
- first study started
- 2003
Keep track of what changes. Save the Probiotic studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Studies by the year they started
433 studies that test it; most in 2024 (55); 2 more planned to start later
| Year | Studies |
|---|---|
| 2003 | 1 |
| 2005 | 1 |
| 2006 | 2 |
| 2007 | 5 |
| 2008 | 2 |
| 2009 | 7 |
| 2010 | 5 |
| 2011 | 8 |
| 2012 | 19 |
| 2013 | 15 |
| 2014 | 9 |
| 2015 | 18 |
| 2016 | 22 |
| 2017 | 25 |
| 2018 | 21 |
| 2019 | 16 |
| 2020 | 23 |
| 2021 | 34 |
| 2022 | 29 |
| 2023 | 39 |
| 2024 | 55 |
| 2025 | 49 |
| 2026 | 28 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 9
- Phase 1
- 22
- Phase 2
- 65
- Phase 3
- 31
- Phase 4
- 20
- No phase
- 311
What it is tested for
Each study’s main condition, where its own words name it.
- Obesity
- 17
Who runs them
Industry 157 · Other 279
Wecare Probiotics Co., Ltd. (47) · Min-Tze LIONG (12) · The Archer-Daniels-Midland Company (9) · Lallemand Health Solutions (9) · University of Copenhagen (9) · Danisco (8) · AB Biotics, SA (7) · Probi AB (7)
Often tested with
Tested in the same studies.
Prebiotics (9) · Rifaximin (2) · Zinc (2) · Omega-3 fatty acid (2) · Vitamin D (2) · Amoxicillin (2) · Fish Oils (2) · Zinc Acetate (1)
Studies
Open first, then newest update. How each study uses Probiotic is read from its arms, and is right about nine times in ten.
Testing it · 436
- Early Probiotic Research: Open-label Functional Intervention and Longitudinal Evaluation in Healthy AdultsNot yet recruitingNot applicableOneCarbonNCT07841457Written as Probiotic Supplement (1C-01)
- Probiotic Mixture (L. Rhamnosus GG and L. Plantarum 299V) In Pediatric Irritable Bowel SyndromeRecruitingNot applicableUniversity of BariNCT07125625Written as Experimental arm: probiotic
- A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)RecruitingNot applicableMemorial Sloan Kettering Cancer CenterNCT06055894Written as Probiotic
- A Real-world Study of Gastrointestinal Health and Mental Wellness in U.S. Adults Following 12 Weeks of Probiotic Supplementation.Not yet recruitingNot applicableNovonesisNCT07849036Written as Probiotic
- The Gut - PRO StudyRecruitingPhase 1University of Wisconsin, MadisonNCT07413744Written as Probiotic
- R-2487 in Patients With Sjogren's Syndrome (SS)Not yet recruitingPhase 1Rise Therapeutics LLCNCT06297213Written as R-2487
- Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) PatientsRecruitingNot applicableCentre hospitalier de l'Université de Montréal (CHUM)NCT06051123Written as Probiotic
- CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer TrialRecruitingPhase 2University of California, San FranciscoNCT06949800Written as EXE-346 Probiotic
- Development of Smart Food /Nutraceutical Solutions Dedicated to Cardiometabolic Disorders in AgeingRecruitingNot applicableAzienda Ospedaliero Universitaria Maggiore della CaritaNCT07817290Written as Probiotic
- Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Pylori InfectionRecruitingPhase 2Tanta UniversityNCT07293910Written as Probiotic
- Therapeutic Potential of a Synbiotic to Improve Mental Health in Subjects With Obesity.RecruitingNot applicableCelia BañulsNCT06901739Written as Synbiotic
- Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCTRecruitingPhase 2Vanderbilt University Medical CenterNCT05288790Written as Probiotic
- Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and KneeEnrolling by invitationPhase 4Boston Medical CenterNCT06636669Written as Probiotic
- Effects of Probiotic Supplementation on Gut Health, Immune Response, and Well-BeingRecruitingNot applicableOrthomol Pharmazeutische Vertiebs GmbHNCT07779265Written as Probiotic capsules
- Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum ChemotherapyRecruitingEarly Phase 1Ohio State University Comprehensive Cancer CenterNCT07144826Written as Probiotic
- Probiotic Research for Mental Health in Adult VolunteersNot yet recruitingNot applicableMental Health Centre Copenhagen, Bispebjerg and Frederiksberg HospitalNCT07751614Written as Probiotic
- The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV StudyRecruitingNot applicableUniversity of FloridaNCT05090267Written as Probiotic Supplement
- Effect of a Probiotic Formula in Mild Cognitive ImpairementRecruitingNot applicableUniversidad Complutense de MadridNCT06670807Written as Probiotic Arm
- Stress-buffering and Sleep Disturbance-resilient Effects of a Dual Bifidobacterium Longum Combination Under Short-term TravelNot yet recruitingPhase 2Min-Tze LIONGNCT07511855Written as Probiotic
- Efficacy and Safety of Probiotics for Anxiety DepressionRecruitingNot applicableMoon (Guangzhou) Biotechnology Co., Ltd.NCT07331987Written as Probiotic
See all 436 studies that test Probiotic →
Given in every arm · 4 — Probiotic is usual care beside what is tested
- Probiotics Combined With Targeted Therapy Plus Immunotherapy in Bladder-Preserving Setting for Patients With MIBCNot yet recruitingPhase 2chenxuNCT07474064Written as Probiotic
- Low-FODMAP Diet and Probiotics: Effects on Gut, Behavior, and Microbiota in Children With Autism Spectrum DisorderCompletedNot applicableMarmara University Pendik Training and Research HospitalNCT07086157Written as Probiotic
- National Multicenter Interventional Study Aimed at Evaluating the Effect on the Intestinal Microbiota in Chronically Frail Patients Who Share Alterations in Intestinal Function.CompletedNot applicableInstitute of Biomedical Technologies-National Research Council, ItalyNCT06005506Written as Probiotic
- Study Of Dacomitinib (PF-00299804) In Advanced NSCLC Patients (Post Chemo Or Select First Line) To Evaluate Prophylactic Intervention On Derm And GI AEs And PROCompletedPhase 2PfizerNCT01465802Written as Probiotic
As the comparator · 7 — what is tested is compared with Probiotic
- Gfree - For Improved Blood Sugar and Reduced Inflammation.RecruitingNot applicableGöteborg UniversityNCT05894746Written as probiotic
- Fecal Microbiota Transplantation in the Treatment of Major LARSNot yet recruitingNot applicablePeking University People's HospitalNCT06475430Written as Formulated probiotic supplements
- The Impact of Probiotics on Bariatric Treatment OutcomesActive, not recruitingNot applicableUniversity of Warmia and Mazury in OlsztynNCT07258732Written as Probiotic
- ZOE BIOME Study: Biotics Influence on Microbiome EcosystemCompletedNot applicableKing's College LondonNCT06231706Written as Probiotic capsule
- Effects of Triphala and VSL#3 Probiotic Supplementation on Stool Microbiome Profiles and InflammationTerminatedNot applicableUniversity of California, San DiegoNCT03907501Written as Probiotic
- Effect of Prebiotics and/or Probiotics on Uremic Toxins and Inflammation Markers in Peritoneal Dialysis PatientsStatus unknownNot applicableUnidad de Investigacion Medica en Enfermedades RenalesNCT03770611Written as Probiotic
- Effects of Probiotics and/or Prebiotics on the Duration of Diarrhea and Hospitalization in ChildrenCompletedPhase 4Eskisehir Osmangazi UniversityNCT01927094Written as Probiotic