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Crohn Disease clinical trials

The registry lists 1,992 studies for Crohn Disease across more than 10 countries. 477 are recruiting or about to start. 1,399 of them are mainly about Crohn Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

ClinicalTrials.gov finds 2,118 studies for Crohn Disease. How that becomes 1,990 here

This page counts the studies the registry files under Crohn Disease, and those it files under no condition that list Crohn Diseasethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 2,118Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −19List Crohn Disease as a condition, but the registry did not file them under itMost often written as “Pediatric Crohn's Disease” (5), “Pediatric Crohns Disease” (4), and “Perianal Crohn Disease” (2). The registry filed them under other conditions only, most often Pediatric Crohn's disease (5) and Inflammatory Bowel Diseases (4).
  3. −109Match it another way74 name it in the title, 3 in a keyword, and 32 by a synonym or other text the search reads.
  4. 1,990The count on this page41 of them list Crohn Disease in their own words; the registry filed them under no condition.

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Status

Completed
894
Recruiting
353
Status unknown
233
Terminated
212
Not yet recruiting
101
Active, not recruiting
91

Phase

Phase 2
325
Phase 3
243
Phase 1
172
Phase 4
153
Early Phase 1
20

Where

United States
660
France
316
Canada
286
Germany
217
United Kingdom
216
Italy
205

Who runs them

Takeda (69) · AbbVie (46) · Sixth Affiliated Hospital, Sun Yat-sen University (34) · Janssen Research & Development, LLC (25) · Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives (22) · Mayo Clinic (21) · Assistance Publique - Hôpitaux de Paris (19) · Jinling Hospital, China (17)

What is being tested here

Drugs under test in Crohn Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Infliximab101241
Vedolizumab101639
Risankizumab7816
Mirikizumab7410
Guselkumab6812
Adalimumab32441
Ustekinumab3921
Duvakitug325
Zasocitinib303
Upadacitinib248

Drug classes tested here Antimetabolites 5 open · JAK inhibitors 5 open · Tyrosine kinase inhibitors (TKIs) 5 open · Corticosteroids 4 open · Alkylating agents 4 open

Coming up

49phase 3 studies under way
171studies finish main data collection within a year12 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 353 Crohn Disease studies recruiting now, 154 (44%) set no upper age limit and 144 (41%) stop at 75 or younger. 95 (27%) take children under 18. 9 (3%) are for women only and 3 (1%) for men only; 56 (16%) take healthy volunteers.

Recruiting studies that take each age, of 353
AgeWomenMen
1061 (17%)59 (17%)
18328 (93%)322 (91%)
30312 (88%)306 (87%)
40311 (88%)306 (87%)
50308 (87%)302 (86%)
65295 (84%)291 (82%)
75249 (71%)244 (69%)
85173 (49%)168 (48%)

Across all 1,992 studies, recruiting or not: 43% stop at 75 or younger and 24% at 65; 24% take children; 2% are for women only and 1% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Crohn Disease studies take

Of 88 phase 3 interventional studies under Crohn Disease, half reached primary completion within 49 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 122 mo10–41 · 61 studies16 mo5–28 · 33 studies—
Phase 234 mo23–51 · 83 studies33 mo20–45 · 56 studies—
Phase 349 mo36–69 · 88 studies46 mo35–69 · 70 studies—
Phase 456 mo35–68 · 70 studies—56 mo44–71 · 54 studies
Interventional, no phase45 mo21–65 · 300 studies—46 mo22–67 · 288 studies
Observational41 mo29–88 · 304 studies36 mo28–60 · 73 studies47 mo32–101 · 231 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting6

Show 1 more

Stopped3

Newly registered11

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Studies

Recruiting first, then most recently updated. Showing 50 of 1,992. Browse all 1,992 → or search them.