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Esophageal Neoplasms clinical trials

The registry lists 1,873 studies for Esophageal Neoplasms across more than 10 countries. 501 are recruiting or about to start. 1,148 of them are mainly about Esophageal Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 2 narrower conditions too, such as Esophageal Squamous Cell Carcinoma: 2,546 studies, 783 open.

ClinicalTrials.gov finds 3,136 studies for Esophageal Neoplasms. How that becomes 1,874 here

This page counts the studies the registry files under Esophageal Neoplasms, and those it files under no condition that list Esophageal Neoplasmsthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 3,136Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −594Filed under a narrower condition, counted on its own pageEsophageal Squamous Cell Carcinoma 473 · Adenocarcinoma Of Esophagus 114
  3. −8List Esophageal Neoplasms as a condition, but the registry did not file them under itMost often written as “Gastro-esophageal Cancer” (2), “Advanced Esophageal Cancers” (1), and “Lower Esophageal Cancer” (1). The registry filed them under other conditions only, most often Neoplasms (3) and Carcinoma, Non-Small-Cell Lung (2).
  4. −662Match it another way66 name it in the title, 7 in a keyword, and 589 by a synonym or other text the search reads.
  5. 1,872Counted here and found by its search29 of them list Esophageal Neoplasms in their own words; the registry filed them under no condition.
  6. +2
    Counted here, but its search does not find them
  7. 1,874The count on this page

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Status

Completed
749
Recruiting
387
Status unknown
292
Terminated
167
Active, not recruiting
107
Not yet recruiting
102

Phase

Phase 2
627
Phase 1
386
Phase 3
138
Phase 4
29
Early Phase 1
11

Where

United States
675
China
502
United Kingdom
111
France
93
Netherlands
90
Germany
84

Who runs them

National Cancer Institute (NCI) (45) · Memorial Sloan Kettering Cancer Center (42) · M.D. Anderson Cancer Center (29) · Fudan University (27) · Sun Yat-sen University (26) · National Taiwan University Hospital (24) · Chinese Academy of Medical Sciences (23) · Tianjin Medical University Cancer Institute and Hospital (23)

What is being tested here

Drugs under test in Esophageal Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Paclitaxel111278
Tislelizumab7212
Pembrolizumab6419
Sintilimab6410
Adebrelimab606
Camrelizumab5216
Nimotuzumab5212
Carboplatin4434
Nivolumab4118
Anlotinib407

Drug classes tested here Immune checkpoint inhibitors 63 open · Antimitotic agents 12 open · Tyrosine kinase inhibitors (TKIs) 11 open · Antibody-drug conjugates (ADCs) 6 open · Antimetabolites 4 open

Coming up

42phase 3 studies under way
166studies finish main data collection within a year8 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 387 Esophageal Neoplasms studies recruiting now, 245 (63%) set no upper age limit and 75 (19%) stop at 75 or younger. 19 (5%) take children under 18. 2 (1%) are for women only and 1 (<1%) for men only; 36 (9%) take healthy volunteers.

Recruiting studies that take each age, of 387
AgeWomenMen
1014 (4%)14 (4%)
18349 (90%)348 (90%)
30368 (95%)367 (95%)
40372 (96%)371 (96%)
50374 (97%)373 (96%)
65375 (97%)374 (97%)
75369 (95%)368 (95%)
85286 (74%)285 (74%)

Across all 1,873 studies, recruiting or not: 18% stop at 75 or younger and 1% at 65; 6% take children; <1% are for women only and <1% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Esophageal Neoplasms studies take

Of 198 phase 2 interventional studies under Esophageal Neoplasms, half reached primary completion within 52 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 148 mo29–76 · 125 studies51 mo34–70 · 77 studies40 mo25–76 · 48 studies
Phase 1/261 mo43–92 · 74 studies——
Phase 252 mo33–78 · 198 studies—55 mo33–85 · 174 studies
Phase 361 mo34–113 · 57 studies——
Interventional, no phase46 mo23–96 · 218 studies—46 mo23–96 · 209 studies
Observational60 mo33–252 · 174 studies—81 mo32–252 · 152 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting3

Results posted1

Stopped1

Newly registered5

Studies

Recruiting first, then most recently updated. Showing 50 of 1,873. Browse all 1,873 → or search them.