Fractures, Bone clinical trials
The registry lists 723 studies for Fractures, Bone across more than 10 countries. 114 are recruiting or about to start. 337 of them are mainly about Fractures, Bone (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 29 narrower conditions too, such as Hip Fractures: 3,408 studies, 680 open.
ClinicalTrials.gov finds 4,417 studies for Fractures, Bone. How that becomes 722 here
This page counts the studies the registry files under Fractures, Bone, and those it files under no condition that list Fractures, Bonethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 4,417Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −2,615Filed under a narrower condition, counted on its own pageHip Fractures 779 · Wrist Fractures 293 · Ankle Fractures 161 · Femoral Neck Fractures 153 · Femoral Fractures 135 · Spinal Fractures 127 · 23 more
- −17List Fractures, Bone as a condition, but the registry did not file them under itMost often written as “Facial Bones Fracture” (3), “Long Bone Fracture” (2), and “Nasal Bone Fracture” (2). The registry filed 8 of them under no condition at all, and the others under other conditions only, most often Wounds and Injuries (4) and Wound Infection (2).
- −1,063Match it another way28 name it in the title, 5 in a keyword, and 1,030 by a synonym or other text the search reads.
- 722The count on this page
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Status
Who runs them
National Taiwan University Hospital (11) · McMaster University (9) · Zimmer Biomet (8) · University of British Columbia (7) · Sheffield Children's NHS Foundation Trust (7) · Assistance Publique - Hôpitaux de Paris (7) · Colaris, Joost, M.D. (6) · Riphah International University (6)
What is being tested here
Drugs under test in Fractures, Bone studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ketamine | 1 | 4 | 10 |
| Denosumab | 1 | 5 | 7 |
| Ibuprofen | 1 | 1 | 6 |
| Omega-3 fatty acid | 1 | 1 | 3 |
| Vancomycin | 1 | 0 | 2 |
| Sufentanil | 1 | 0 | 2 |
| Dexmedetomidine | 1 | 0 | 2 |
| Iloprost | 1 | 0 | 1 |
| P-prf | 1 | 0 | 1 |
| Buprenorphine | 1 | 0 | 1 |
Drug classes tested here Opioids 2 open · NSAIDs 2 open · Local anesthetics 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation · Phase 3 · Naveen Poonai
- Sep 2027PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation · Phase 3 · Major Extremity Trauma Research Consortium
- Nov 2026A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD) · Hoffmann-La Roche
- Nov 2026Mindfulness in Fracture Recovery and Reduction of Opioid Reliance: Evaluating the Feasibility of Implementing a Brief, Mindfulness-based Intervention to Manage Pain and Anxiety Before and After Fracture Surgery · McMaster University
- Dec 2026DePuy Synthes Variable Angle LCP Patella Plating System Study · Hartford Hospital
- Dec 2026Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department · The Cooper Health System
- Dec 2026Fragility Fracture Liaison Service and Anti-osteoporosis Medication Monitoring Service Study · National Taiwan University Hospital
- Dec 2026Prospective Registry to Evaluate Outcomes of NanoBone® Bone Graft in Acute Trauma · Artoss Inc.
- Dec 2026Clinical Effectiveness of Robot-assisted Gait Training in Patients With Lower Limb Burns Accompanied by Fractures: Pilot Study · Hangang Sacred Heart Hospital
- Dec 2026Use of ETElcalcetidefor pReserving vitamiN K-dependent proteIn activiTY ITAlian Study · Istituto di Fisiologia Clinica CNR
Who these studies take
Of the 70 Fractures, Bone studies recruiting now, 35 (50%) set no upper age limit and 21 (30%) stop at 75 or younger. 17 (24%) take children under 18. 4 (6%) are for women only and 0 (0%) for men only; 14 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 16 (23%) | 16 (23%) |
| 18 | 53 (76%) | 51 (73%) |
| 30 | 54 (77%) | 52 (74%) |
| 40 | 54 (77%) | 52 (74%) |
| 50 | 57 (81%) | 55 (79%) |
| 65 | 54 (77%) | 52 (74%) |
| 75 | 50 (71%) | 49 (70%) |
| 85 | 45 (64%) | 44 (63%) |
Across all 723 studies, recruiting or not: 33% stop at 75 or younger and 26% at 65; 27% take children; 7% are for women only and 2% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Fractures, Bone studies take
Of 19 phase 4 interventional studies under Fractures, Bone, half reached primary completion within 34 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 39 mo26–46 · 14 studies | — | — |
| Phase 4 | 34 mo20–75 · 19 studies | — | — |
| Interventional, no phase | 29 mo12–57 · 166 studies | — | 29 mo12–57 · 148 studies |
| Observational | 46 mo20–124 · 86 studies | — | 43 mo20–88 · 66 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting2
- The Effect of Digital Education for Osteoporosis Patients on Fracture Risk and Related Health Outcomes.Nov 10, 2026NCT06603545
- Morphine or Ketamine for AnalgesiaOct 20, 2026NCT06835504
Newly registered6
- Local Iloprost Therapy to Promote Bone Healing in High Risk FracturesNov 9, 2026NCT07924722
- A Clinical Study to Collect Real-wordt Data on Safety and Clinical Performance of the VCFix Spinal System for Treatment of Vertebral Compression Fractures of (Suspected) Osteoporotic Origin.Nov 5, 2026NCT07920484
- Evaluation of the Diagnostic Potential of Nanox.ARC Tomosynthesis System for Different DiseasesOct 28, 2026NCT07900412
- Nerve Block Resolution Time Display and Pain ComplaintsOct 21, 2026NCT07887516
- Full-Contour Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation BehaviorOct 15, 2026NCT07876466
Show 1 moreShow fewer
- REMS vs DXA for Osteoporosis Diagnosis and Fracture Risk PredictionOct 15, 2026NCT07876882
Studies
Recruiting first, then most recently updated. Showing 50 of 723. Browse all 723 → or search them.
- The Effect of Digital Education for Osteoporosis Patients on Fracture Risk and Related Health Outcomes.RecruitingNCT06603545Not applicable1 country
- Local Iloprost Therapy to Promote Bone Healing in High Risk FracturesNot yet recruitingNCT07924722Phase 2
- Pediatric Orthopaedic Implant Safety & EfficacyRecruitingNCT053619801 country
- A Clinical Study to Collect Real-wordt Data on Safety and Clinical Performance of the VCFix Spinal System for Treatment of Vertebral Compression Fractures of (Suspected) Osteoporotic Origin.RecruitingNCT079204841 country
- Trial of Social Work Services in Fracture Clinic SettingRecruitingNCT06973655Not applicable2 countries
- Evaluation of the Diagnostic Potential of Nanox.ARC Tomosynthesis System for Different DiseasesRecruitingNCT07900412Not applicable1 country
- Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic FracturesRecruitingNCT06113211Phase 41 country
- Repair of Extra-articular Fractures of the Metacarpals and First Phalanges of the Long FingersNot yet recruitingNCT07186829Not applicable1 country
- Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study)Enrolling by invitationNCT07268547Phase 41 country
- Nerve Block Resolution Time Display and Pain ComplaintsNot yet recruitingNCT07887516Not applicable
- Full-Contour Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation BehaviorRecruitingNCT078764661 country
- Morphine or Ketamine for AnalgesiaRecruitingNCT06835504Phase 31 country
- Study on Outcomes of Proximal Humerus FracturesNot yet recruitingNCT07060664Not applicable1 country
- Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection AlgorithmsRecruitingNCT07853768Not applicable1 country
- REMS vs DXA for Osteoporosis Diagnosis and Fracture Risk PredictionRecruitingNCT078768821 country
- Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation BehaviorRecruitingNCT019743621 country
- Mindfulness in Fracture Recovery and Reduction of Opioid Reliance: Evaluating the Feasibility of Implementing a Brief, Mindfulness-based Intervention to Manage Pain and Anxiety Before and After Fracture SurgeryRecruitingNCT07486505Not applicable1 country
- Opioid Analgesia Impacts on Neurological DevelopmentNot yet recruitingNCT078559521 country
- X-BS Ortho Bone Graft StudyNot yet recruitingNCT06326827Not applicable
- Epidemiological and Statistical Study of Facial Traumatic Fractures at Assiut University Trauma HospitalNot yet recruitingNCT07827209
- Exactech Shoulder Post Market Clinical Follow-up StudyRecruitingNCT056037286 countries
- Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture CareRecruitingNCT042990221 country
- Lipofilling in Operative Hand Fracture TreatmentNot yet recruitingNCT07815444Not applicable1 country
- PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After FixationRecruitingNCT05699174Phase 31 country
- LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)Enrolling by invitationNCT066706511 country
- Bio-Integrative, Fiber-Reinforced Kneebar for Treating Subchondral Insufficiency of the KneeEnrolling by invitationNCT061385481 country
- OSTEOMICS: Identifying Regulators of Bone HomeostasisRecruitingNCT057328701 country
- Calcium-Rich Food Versus Calcium Carbonate for Bone HealthNot yet recruitingNCT07763509Not applicable1 country
- Ultrasound Assessment of Pediatric Fracture Healing With the PLUS ScoreNot yet recruitingNCT077557871 country
- Multimodal Decision Support for Perioperative Risk Stratification in Older Adults Undergoing Surgery for FractureNot yet recruitingNCT07736469
- Naringenin Supplementation in Bone Fracture PatientsRecruitingNCT06612762Not applicable1 country
- Diagnostic Accuracy and Operational Efficiency of Point-of-Care Ultrasound (POCUS) in Long Bone Fractures: A Brazilian Multicenter StudyNot yet recruitingNCT07728227
- Use of a Vibration Tool for Postoperative Pain Control in Distal Radius FracturesNot yet recruitingNCT05318729Not applicable1 country
- Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency DepartmentRecruitingNCT07430345Phase 1/21 country
- A Clinical Study Evaluating the Safety and Efficacy of the VCFix Spinal System for Treatment of Vertebral Compression FracturesRecruitingNCT07301749Not applicable2 countries
- Platelet-Rich Fibrin (PRF) vs Bone Graft With Membrane for Ridge Preservation After Tooth ExtractionNot yet recruitingNCT07595198Not applicable
- Randomized Fracture Liaison ServicesEnrolling by invitationNCT031787991 country
- Clinical Effectiveness of Robot-assisted Gait Training in Patients With Lower Limb Burns Accompanied by Fractures: Pilot StudyEnrolling by invitationNCT07578753Not applicable1 country
- Virtual Reality in Reducing Acute Orthopedic PainRecruitingNCT06624969Not applicable1 country
- Continuous Passive Motion Following Fixation of Pelvic and Knee FracturesRecruitingNCT04389749Not applicable1 country
- Cannulated Bone Bolt® Screw System Versus Standard Cannulated Screw System Fixation for Pelvic FracturesEnrolling by invitationNCT072092801 country
- Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary NailsNot yet recruitingNCT07536581Not applicable1 country
- Study in Patients With Osteoporosis and Fragility Fractures to Estimate the Extent and Impact of Delayed Administration of Anti-fracture TherapyNot yet recruitingNCT075124531 country
- Study of ICG Fluorescence Imaging in Open Fracture and Infection PatientsRecruitingNCT067936441 country
- Gait and Bone Health in SMARecruitingNCT074001981 country
- Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF InvestigationRecruitingNCT05555459Not applicable1 country
- Evaluating a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture)RecruitingNCT06438640Not applicable1 country
- Clinical Validation of RBfracture for Diagnosing Trauma-related Musculoskeletal InjuriesNot yet recruitingNCT07421791
- FX Shoulder Prospective Clinical StudyRecruitingNCT060788651 country
- Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children.Not yet recruitingNCT06968546Phase 21 country