Rib Fractures clinical trials
The registry lists 126 studies for Rib Fractures across more than 10 countries. 28 are recruiting or about to start. 108 of them are mainly about Rib Fractures (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
Assiut University (8) · Stanford University (5) · Zimmer Biomet (4) · University of California, San Diego (4) · Sahlgrenska University Hospital (4) · National Taiwan University Hospital (3) · Ankara City Hospital Bilkent (3) · Chang Gung Memorial Hospital (3)
What is being tested here
Drugs under test in Rib Fractures studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ropivacaine | 1 | 0 | 6 |
| Dexmedetomidine | 1 | 1 | 2 |
| Suzetrigine | 1 | 0 | 1 |
| Bupivacaine | 0 | 0 | 5 |
| Lidocaine | 0 | 0 | 4 |
| Ketamine | 0 | 0 | 3 |
| Liposomal Bupivacaine | 0 | 0 | 3 |
| Ibuprofen | 0 | 0 | 1 |
| Lidocaine Topical | 0 | 0 | 1 |
| Lidoderm | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jul 2027Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs · Phase 3 · Assiut University
- Oct 2027Comparison of Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Ultrasound-Guided Erector Spinae Plane Block for Acute Pain Management in Patients With Traumatic Rib Fractures · Phase 3 · Assiut University
- Nov 2026Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU · Brigham and Women's Hospital
- Dec 2026Costal Fracture Assessment for Relief and Enhancement of Quality of Life · Ospedali Riuniti Trieste
- Dec 2026Role of Nerve Block in Management of Multiple Rib Fractures · Assiut University
- Dec 2026Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib Fractures · Niguarda Hospital
- Dec 2026Comparison of Mixed Reality and Ultrasound Localization Techniques for Surgical Stabilization of Rib Fractures · National Taiwan University Hospital
- Jan 2027Point of Care Ultrasound (POCUS) for Diagnosis and Treatment of Fractures in the Costal Cartilage · Sahlgrenska University Hospital
- Feb 2027INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures · Zachary Warriner
- Feb 2027Cryo Rib Fracture Study · University of Minnesota
Who these studies take
Of the 13 Rib Fractures studies recruiting now, 9 (69%) set no upper age limit and 1 (8%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (15%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 13 (100%) | 13 (100%) |
| 30 | 13 (100%) | 13 (100%) |
| 40 | 13 (100%) | 13 (100%) |
| 50 | 13 (100%) | 13 (100%) |
| 65 | 13 (100%) | 13 (100%) |
| 75 | 12 (92%) | 12 (92%) |
| 85 | 11 (85%) | 11 (85%) |
Across all 126 studies, recruiting or not: 15% stop at 75 or younger and 8% at 65; 5% take children; 0% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Rib Fractures studies take
Of 40 interventional studies with no phase under Rib Fractures, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 23 mo15–37 · 40 studies | — | 23 mo15–37 · 40 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Newly registered1
- Magnesium-Enhanced ESPB for Respiratory Recovery and Analgesia in Unilateral Rib FracturesNov 10, 2026NCT07929402
Studies
Recruiting first, then most recently updated. Showing 50 of 126. Browse all 126 → or search them.
- Magnesium-Enhanced ESPB for Respiratory Recovery and Analgesia in Unilateral Rib FracturesNot yet recruitingNCT07929402Not applicable
- INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib FracturesRecruitingNCT05642026Phase 41 country
- Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain Management in Patients With Traumatic Rib FracturesRecruitingNCT07756047Not applicable1 country
- Comparison of Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Ultrasound-Guided Erector Spinae Plane Block for Acute Pain Management in Patients With Traumatic Rib FracturesNot yet recruitingNCT07827157Phase 2/3
- Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic TraumaEnrolling by invitationNCT06069154Not applicable1 country
- Comparison of Mixed Reality and Ultrasound Localization Techniques for Surgical Stabilization of Rib FracturesNot yet recruitingNCT07243808
- Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib FracturesRecruitingNCT070327661 country
- SPSIP vs ESP Block for Analgesia After Rib Fracture SurgeryNot yet recruitingNCT07553208Not applicable1 country
- Point of Care Ultrasound (POCUS) for Diagnosis and Treatment of Fractures in the Costal CartilageNot yet recruitingNCT07338617
- Surgery for Unstable Chest Wall Injuries - How Many Fractures Should be Fixed?Not yet recruitingNCT07338656Not applicable1 country
- Zimmer Biomet-RibFix TitanRecruitingNCT074858291 country
- Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib FracturesNot yet recruitingNCT05105399Not applicable1 country
- Deep Breathing Exercises and Incentive Spirometry After Rib FractureRecruitingNCT06853002Not applicable1 country
- Cryo Rib Fracture StudyRecruitingNCT06347874Phase 41 country
- Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib FracturesNot yet recruitingNCT06533904Not applicable1 country
- Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture RibsRecruitingNCT04928300Phase 31 country
- Suzetrigine for Acute Pain Control in Patients With Multiple Rib FracturesEnrolling by invitationNCT07145346Phase 41 country
- Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICURecruitingNCT06538376Not applicable1 country
- UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib FractureRecruitingNCT05865327Not applicable1 country
- Ultrasound Guided Serratus Anterior Plane Block for Rib FracturesRecruitingNCT05748366Not applicable1 country
- Kinesiotaping in TraumaRecruitingNCT05976256Not applicable1 country
- Ultrasound-Guided Mid-Point Transverse Process to Pleura Block Versus Thoracic Paravertebral Block for Pain Management in Patients With Multiple Rib Fractures (A Prospective Randomized Double- Blinded, Non-inferiority Trial )Not yet recruitingNCT06981728Not applicable
- Role of Nerve Block in Management of Multiple Rib FracturesNot yet recruitingNCT06958549Phase 4
- Costal Fracture Assessment for Relief and Enhancement of Quality of LifeNot yet recruitingNCT064058411 country
- Breathing Exercise for Rib FractureRecruitingNCT06222333Not applicable1 country
- RibFix Blu Thoracic Fixation System Versus Non-surgical Treatment in Non-flail Chest Rib FracturesRecruitingNCT051469862 countries
- Prospective Comparative Study Between Ultrasound-guided Continuous Erector Spinae Plane Block and the Use of Intravenous Patient Controlled Analgesia for Management of Pain in Patients With Multiple Fracture RibsNot yet recruitingNCT05975294Not applicable
- A Prospective Randomized Controlled Study Comparing the Clinical Effects of Surgical and Non-surgical Treatment of Low Rib FracturesNot yet recruitingNCT05758870
- Ketamine vs Lidocaine in Traumatic Rib FracturesCompletedNCT04781673Phase 41 country
- Ultrasound for Diagnosing Costochondral Joint SeparationCompletedNCT06766721Not applicable1 country
- Effectiveness of an Innovative Chest Stabilizer in Rib Fracture Treatment: Impact on Respiratory Function, Complications, and Clinical OutcomesActive, not recruitingNCT07238582Not applicable1 country
- Ibuprofen Versus Dexketoprofen in Rib FracturesCompletedNCT07859631Phase 41 country
- Pain as Indication for Operative Treatment of Traumatic Rib FracturesWithdrawnNCT02094807Not applicable1 country
- Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic TraumaTerminatedNCT06626334Not applicable1 country
- Naproxen and Lidocaine Gel Combination for Rib FractureCompletedNCT07706036Not applicable1 country
- Lidocaine Patches in Elderly Patients With Traumatic Rib FracturesTerminatedNCT05714631Phase 41 country
- The Analgesic Effect of Retro-laminar Block Versus Paravertebral Block in Patients With Multiple Fracture RibsCompletedNCT06757803Not applicable1 country
- Real-time Ultrasound Guidance for Thoracic Epidural BlocksWithdrawnNCT051654981 country
- Comparison of Continuous Intravenous Lidocaine Infusion Versus ESP Block for Rib Fracture AnalgesiaWithdrawnNCT04707183Phase 21 country
- Investigation of the Effect of Age and Injury Severity on Short-term Intra-hospital Outcomes After Surgical Stabilized Rib FracturesCompletedNCT064643021 country
- Treatment of Adult Traumatic Rib Fractures With Percutaneous CryoneurolysisCompletedNCT05330611Not applicable1 country
- Rhomboid Intercostal and Sub-Serratus Block for Improving Pulmonary Function and Pain in Patients With Fracture RibsCompletedNCT05898958Not applicable1 country
- Erector Spinae Plane Blocks for the Early Analgesia of Rib Fractures in Trauma: a Feasibility Randomised Controlled Trial With Embedded Qualitative AssessmentCompletedNCT07494851Not applicable1 country
- Early Percutaneous Cryoablation for Pain Control After Rib Fractures Among Elderly PatientsCompletedNCT04482582Not applicable1 country
- Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled TrialCompletedNCT05321121Phase 41 country
- Ultrasound Guided Serratus Anterior Plane Block in ED Patients With Rib FracturesCompletedNCT06299137Early Phase 11 country
- Analgesic Techniques for Rib FracturesActive, not recruitingNCT06519929Phase 41 country
- Impact of Time Interval Between Trauma and Operation on Clinical Outcome in Patients With Delayed Rib Fixation (Nonunion)Active, not recruitingNCT067880671 country
- Ultrasound Guided Emergency Physician Performed Erector Spinae Nerve Block for Rib Fracture AnalgesiaWithdrawnNCT04168710Phase 1/2
- PVB vs Ketamine/Lidocaine in Rib Fracture PatientsTerminatedNCT04413799Early Phase 11 country