Dentin Sensitivity clinical trials
The registry lists 282 studies for Dentin Sensitivity across more than 10 countries. 45 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-21.
Status
- Completed
- 204
- Not yet recruiting
- 21
- Status unknown
- 21
- Recruiting
- 18
- Active, not recruiting
- 8
- Enrolling by invitation
- 6
Phase
- Phase 3
- 30
- Phase 2
- 25
- Phase 4
- 20
- Phase 1
- 11
- Early Phase 1
- 3
Where
- United States
- 55
- Brazil
- 50
- Egypt
- 31
- Pakistan
- 16
- United Kingdom
- 14
- China
- 13
Who runs them
GlaxoSmithKline (26) · Universidade Federal do Para (23) · HALEON (20) · Cairo University (17) · Procter and Gamble (11) · Universidade Federal Fluminense (7) · University of Sao Paulo (7) · Colgate Palmolive (6)
Studies
Recruiting first, then most recently updated. Showing 50 of 282 — search for more.
- Dentine Hypersensitivity Using Dentine Adhesive With Strontium-doped Bioactive Glass-CeramicRecruitingNCT07628712Not applicable1 country
- A Clinical Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine HypersensitivityNot yet recruitingNCT07802886Not applicable1 country
- Effectiveness of Two Different Desensitizing Dental VarnishesRecruitingNCT07622043Not applicable1 country
- Comparative Efficacy of Different Dentin Occluding Toothpaste TechnologiesRecruitingNCT07664592Phase 31 country
- Modified Coronally Advanced Tunnel for Mandibular Lingual Root CoverageEnrolling by invitationNCT07590960Not applicable1 country
- Effect of Bleaching Regimen With Different Activation Modes on Color Stability, Surface Roughness, Tooth Sensitivity and Patient SatisfactionEnrolling by invitationNCT07493941Not applicable1 country
- Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical StudyNot yet recruitingNCT07648147Not applicable1 country
- Effect of Fluoride Varnish Formulation on the Management of Dentin HypersensitivityRecruitingNCT07286344Not applicable1 country
- Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.RecruitingNCT071953571 country
- A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity SufferersRecruitingNCT073371091 country
- Hydroxyapatite-Based Home Treatment for Dentin Sensitivity in Celiac PatientsRecruitingNCT07069127Not applicable1 country
- Dipotassium Oxalate for Postoperative Sensitivity in NCCLsNot yet recruitingNCT07540299Not applicable1 country
- Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized NightguardsRecruitingNCT07464197Not applicable1 country
- Diode Laser Plus CPP-ACPF vs CPP-ACPF Alone for Dentin HypersensitivityNot yet recruitingNCT07449169Not applicable
- Hydroxyapatite Toothpastes and Enamel Remineralization:RecruitingNCT07069218Not applicable1 country
- Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical StudyNot yet recruitingNCT07329244Not applicable1 country
- Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite RestorationsNot yet recruitingNCT07188142Phase 2/31 country
- The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.RecruitingNCT07173296Not applicable1 country
- Comparative Efficacy of Laser Systems and Fluoride in Managing Dentinal Hypersensitivity: RCTNot yet recruitingNCT07141576Not applicable
- Clinical Effectiveness of Episodic Use of Bioactive Silica Based Versus in Management of Dentin Hypersensitivity (A 6m Randomized Clinical Trial)Not yet recruitingNCT07120139Not applicable1 country
- BIOSILITACE AS A DESENSITIZING AGENTIN HMINot yet recruitingNCT07080645Not applicable1 country
- Three Different Topically Applied Materials as Non-invasive Treatment of Sensitivity in Permanent Teeth With Molar Incisor HypomineralizationNot yet recruitingNCT07056855Not applicable
- Effect of an Experimental Cannabidiol Gel on Tooth SensitivityNot yet recruitingNCT07027566Phase 11 country
- Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin HypersensitivityNot yet recruitingNCT06557980Not applicable
- Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hypersensitivity: an In-Vivo StudyNot yet recruitingNCT06854068Not applicable
- Exposed Hypersensitive Dentin Treated with Fluoride Iontophoresis with Remineralizing AgentsEnrolling by invitationNCT06837779Not applicable1 country
- Using Calcium Hydroxylapatite to Treat Gum Recession and Tooth HypersensitivityEnrolling by invitationNCT06826391Not applicable1 country
- Efficacy of a Potassium Nitrate Containing Herbal Mouthwash to a Potassium Oxalate Mouthwash in Dentinal HypersensitivityRecruitingNCT06627790Phase 31 country
- Efficacy and Safety Assessment of Experimental Bleaching AgentsNot yet recruitingNCT06802614Not applicable1 country
- Efficacy of Tooth Bleaching With 35% and 6% Hydrogen Peroxide in Primary DentitionNot yet recruitingNCT05789004Phase 1/2
- Neurological Responses in Patients with Dentine HypersensitivityRecruitingNCT066336271 country
- Dentine Hypersensitivity Management KAP StudyEnrolling by invitationNCT065822381 country
- Dentin Hypersensitivity - Varnish or Laser?Not yet recruitingNCT06539286Not applicable
- Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.RecruitingNCT06532526Not applicable1 country
- A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DHRecruitingNCT06463938Not applicable1 country
- Efficacy of Formulated Eggshell Derived Nano-hydroxyapatite Containing Toothpaste With and Without Addition of Fluoride vs. Conventional Desensitizing Fluoride Containing Toothpaste in Management of Dentin HypersensitivityNot yet recruitingNCT06493500Phase 1
- Effect of Pregabalin Gel in Controlling Cervical Dentin HypersensitivityNot yet recruitingNCT06417580Phase 2
- The Effect of Using Desensitizers Containing S-PRG In Treatment Of Dentin Hypersensitivity Over 6 Months: A Randomized Clinical TrialNot yet recruitingNCT06276777Not applicable1 country
- Reduction of Dentine Hypersensitivity After Use of Different DentifricesRecruitingNCT06273930Phase 11 country
- Dentine Hypersensitivity Treated With Laser and Fluoride.Enrolling by invitationNCT06202495Not applicable1 country
- Pregabalin Gel in Reducing Post-operative Tooth Sensitivity Surgery Caused by Bleaching With 35% Hydrogen PeroxideNot yet recruitingNCT06180707Phase 31 country
- Clinical Evaluation of Giomer Based Varnish Versus CPP-ACP Varnish in the Management of Dentin Hypersensitivity: a Randomized Clinical TrialRecruitingNCT06154941Not applicable1 country
- Managing Dentine Hypersensitivity With Silver Diamine Fluoride on Older AdultsRecruitingNCT05392868Phase 21 country
- Grape Seed Extract VS Low Level Laser Therapy for Dentin HypersensitivityRecruitingNCT05927831Not applicable1 country
- Comparison of the Effectiveness of Self Etch Adhesive and Fluoride Varnish in Reducing Hypersensitivity in Patients With Gingival RecessionNot yet recruitingNCT05895526Not applicable1 country
- Polymeric Nano Calcium Fluoride Varnish, Diode Laser, and Their Combination for Dentin HypersensitivityCompletedNCT07418788Not applicable1 country
- Clinical Efficacy of Novel Titanium Oxide Nanoparticle Enriched Bleaching GelCompletedNCT06904118Not applicable1 country
- Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel DentifriceCompletedNCT07215767Phase 31 country
- Color Stability and Tooth Sensitivity of CAD/CAM and Conventional Provisional RestorationsCompletedNCT07781241Not applicable1 country
- Study to Investigate the Effect of Changes in Dentinal Hypersensitivity on Oral Health ParametersCompletedNCT07768969Not applicable1 country