An interventional study of Fluoride Iontophoresis with Acidulated Phosphate Fluoride and Remineralization with sodium fluoride varnish in Dentin Hypersensitivity, sponsored by Al-Azhar University. Enrolling by invitation at 1 site in Egypt. Open to participants aged 35 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-02-20.
Sponsored by Al-Azhar University · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity. It will also learn about the safety of using fluoride iontophoresis with Acidulated phosphate fluoride gel.
The main questions it aims to answer are:
Does the remineralizing agent have the ability to decrease dentin sensitivity?
Researchers will compare Fluoride Iontophoresis with Acidulated Phosphate Fluoride gel , Casein phosphopeptides-Amorphus calcium phosphate (CPP-ACP), nano-hydroxyapptite (NHAP) and -active glass in decreasing dentin hypersensitivity
.
Participants will:
Assess the efficacy of fluoride iontophoresis in remineralization in comparison with other ingredients.
288 studies on the registry are indexed under Dentin Sensitivity; 46 are open to participants now.
This study's planned enrollment of 20 is below the median of 60 across 279 interventional studies indexed under Dentin Sensitivity.
Browse Dentin Sensitivity studies →Al-Azhar University is the lead sponsor of 531 studies on the registry; 172 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
assessmen of iontophoresis effect on flouride ions flush to remineralization of demineralized enamel .The treatment will be assessed and recorded using VAS score immediately after the intervention, 3 months, 6 months and one year later.
Drug: Fluoride Iontophoresis with Acidulated Phosphate Fluoride
All remineralizing agents (Casein phosphopeptides -Amorphus Calcium Phosphate, Nano-hydroxyapatite, and Bioactive glass).
Drug: Remineralization with sodium fluoride varnish
Application of fluoride gel and activated with Iontophoresis electrical pole
CASIN PHOSPHOPEPTIDE AMORPHOUS CALCIUM PHOSPHATE
Visual Analogue Scale
Measurement of sensitivity was performed after each stimulus by a Visual Analogue Scale, which consists of a 10-cm long line; the minimum value is 0 and the maximum value is 10, whether the higher scores mean worse and the lower score means better outcome. The patient's pain limits can suffer through an external stimulus; at 0, one end represents absence of discomfort, and the other represents severe discomfort caused by certain stimuli. Each time the patient is subjected to a stimulus, he or she is requested to point at the interval from 0 to 10, a number to correspond to the pain felt. The convenience of this type of scale is to allow demonstration of the pain intensity with absolute numbers or as a percentage of a maximum value
Time frame: 12 months
Plan to share: No — privacy of patient may be may be photo of device used in the study , photo of treatment
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