An interventional study of 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation and 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation in Bleaching; Satisfactory, Bleaching Sensitivity and Bleaching Efficacy, sponsored by Tanta University. Enrolling by invitation at 1 site in Egypt. Open to participants aged 20 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-06-29.
Sponsored by Tanta University · Not applicable, Interventional, and Treatment
Among 33 studies in Dentin Sensitivity with a site in Egypt — 6 open to participants now, 8 under way, 1 of them phase 3. Dentin Sensitivity · Egypt.
Among the 33 studies in Dentin Sensitivity with a site in Egypt, this one is the 19th largest by planned enrollment of the 32 interventional ones that give a count, is one of 2 that started in 2026, is one of 24 with no phase, and was the 30th registered.
288 studies on the registry are indexed under Dentin Sensitivity; 46 are open to participants now.
Browse Dentin Sensitivity studies →6 of the 33 studies in Dentin Sensitivity with a site in Egypt are open now. Recruiting first, the newest first:
Cairo University · Sites in Egypt
Muhammad Modu · Sites in Egypt
Al-Azhar University · Sites in Egypt
Rawda Hesham Abd ElAziz · Sites in Egypt
Eman Omar Elfarouk · Sites in Egypt
A study can be open while its sites in Egypt have not opened yet or have stopped. Only those recruiting at a site in Egypt →
Of the 18 Dentin Sensitivity studies recruiting now, 6 (33%) set no upper age limit and 11 (61%) stop at 75 or younger; 1 take children under 18; 11 take healthy volunteers.
This study: 20 Years to 35 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
33 studies; the count open now beside each. This study's row is marked.
First in 2017; this study’s year is marked. 2 started in 2026.
This study's planned enrollment of 45 is below the median of 60 across 279 interventional studies indexed under Dentin Sensitivity.
Median enrollment 48 across the 32 interventional studies, 500 across the 1 observational. Of the 20 that completed or were terminated, 0 (0%) have results posted.
This tab as a report to print or save as PDF → With an account.
1 of 33 have an industry lead sponsor. The 10 most frequent:
Tanta University is the lead sponsor of 1,010 studies on the registry; 321 are open to participants now.
Of its 15 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Tanta University has 2 studies filed under Dentin Sensitivity — fewer than ten, so there is no comparison to draw.
1 of the studies in Dentin Sensitivity with a site in Egypt that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06772051Mansoura UniversityClinical Evaluation of Short Dentin Etching | 2026-12-24 |
Among the 33 studies in Dentin Sensitivity with a site in Egypt, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The purpose of this study was to conduct a randomized double-blind clinical trial to examine the efficacy of an in-office bleaching regimen with varied activation modes on color stability, surface roughness, tooth sensitivity, and patient satisfaction.
Tooth discoloration is a common esthetic concern that can negatively impact patients' self-confidence and quality of life. Contemporary restorative dentistry increasingly emphasizes minimally invasive approaches, with vital tooth bleaching emerging as a widely accepted, conservative treatment for managing extrinsic and intrinsic discoloration. The effectiveness of bleaching procedures primarily depends on the oxidative degradation of chromogenic compounds within dental hard tissues, leading to improved tooth color.
In-office bleaching techniques often incorporate various activation modes intended to enhance the efficacy of bleaching agents, accelerate treatment time, and improve clinical outcomes. These activation methods may include light-emitting diode (LED) systems, laser activation, or purely chemical activation without external energy sources. Despite their widespread use, the actual benefit of these activation modalities remains controversial, with conflicting evidence regarding their influence on bleaching effectiveness and associated adverse effects.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants receive in-office bleaching using 35% hydrogen peroxide activated by a dental laser system.
Other: 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation
Participants receive in-office bleaching using 35% hydrogen peroxide activated by a visible light source
Other: 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation
Participants receive in-office bleaching using 35% hydrogen peroxide without any external activation.
Other: 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) - Chemical Activation Only
Application of a 35% hydrogen peroxide bleaching agent (Bleach 'n Smile®) to the labial tooth surfaces, followed by activation using a dental laser according to the manufacturer's recommended parameters. The bleaching procedure is performed in a single clinical session under standardized conditions
Application of a 35% hydrogen peroxide bleaching agent (Bleach 'n Smile®) followed by activation using a dental light-curing unit or LED-based bleaching system, according to manufacturer instructions.
Application of 35% hydrogen peroxide bleaching agent (Bleach 'n Smile®) without the use of external energy sources, allowing the material to act chemically according to manufacturer instructions.
Color Change (ΔE)
Assessment of tooth color change using a digital spectrophotometer (VITA Easyshade® V, Vita Zahnfabrik, Germany). Color measurements will be recorded in the CIE L\*a\*b\* color space, and the overall color difference (ΔE) will be calculated between baseline and subsequent time points.
Time frame: Baseline (pre-bleaching), immediately post-bleaching, 1 month, and 3 months post-treatment
Enamel Surface Roughness (Ra, µm)
Evaluation of changes in enamel surface roughness following bleaching procedures. A profilometer used to record average surface roughness (Ra) values in micrometers (µm)
Time frame: Baseline and immediately after bleaching procedure
Tooth Sensitivity
Assessment of patient-reported tooth sensitivity associated with bleaching procedures. Visual Analog Scale (VAS) ranging from 0 (no sensitivity) to 10 (maximum unbearable sensitivity)
Time frame: Immediately after bleaching, 24 hours post-treatment, and up to 7 days post-treatment
Patient Satisfaction
Evaluation of patient satisfaction regarding esthetic outcomes and overall treatment experience. Validated questionnaire using a Likert scale (e.g., 1 = very dissatisfied to 5 = very satisfied), covering aspects such as perceived color improvement, comfort, and willingness to undergo the procedure again
Time frame: Immediately after treatment and at 3-month follow-up
Plan to share: No
Started Jan 2026 (actual). Primary completion is estimated for Jul 2026, 6 months after the start.
Of 111 non-industry interventional studies with no phase under Dentin Sensitivity, half reached primary completion within 7 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 12. This study's planned 6 months is below that.
Counting every sponsor, half of 144 studies reached it within 6 months; a quarter within 3 and three quarters within 10.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
No contact was published for this record. The registry link below has the sponsor’s details.
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