An interventional study of episodic use of the desensitizing toothpaste and continuous use of the conventional desensitizing toothpaste in Dentin Hypersensitivity, sponsored by Rawda Hesham Abd ElAziz. Not yet recruiting at 1 site in Egypt. Open to participants aged 22 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-08-13.
Sponsored by Rawda Hesham Abd ElAziz · Not applicable, Interventional, and Treatment
The aim of the study to compare the clinical effectiveness of Episodic use of Bioactive Silica Based versus continuous use of fluoride based desensitizing toothpastes in management of dentin hypersensitivity (DH) of adult patients over 6m follow up and evaluating patient satisfaction regarding the treatment provided. Episodic use will be tested as it reflects the effectiveness in a clinical scenario regarding patient compliance and adherence to the treatment where some of the Egyptian patients stop the treatment once improvement occurs due to financial constraints
288 studies on the registry are indexed under Dentin Sensitivity; 46 are open to participants now.
This study's planned enrollment of 50 is below the median of 60 across 279 interventional studies indexed under Dentin Sensitivity.
Browse Dentin Sensitivity studies →Rawda Hesham Abd ElAziz is the lead sponsor of 4 studies on the registry; 2 are open to participants now.
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Patients with DH, VAS ≥ 3 and Schiff sensitivity score needed to be ≥2, indicating that application of a jet of air makes the patient respond and move or requests discontinuation of the stimuli application.
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Exclusion Criteria:
Systematic disease and/ or physical disabilities that may affect participation. • Patients who did any periodontal surgeries within the previous 3 months.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Procedure: episodic use of the desensitizing toothpaste
Procedure: episodic use of the desensitizing toothpaste
Procedure: episodic use of the desensitizing toothpaste
Procedure: continuous use of the conventional desensitizing toothpaste
subjects assigned to episodic treatment will use the assigned toothpaste with the same previous instructions for two 8-week treatment periods, followed by an 8-week phase in which they will use the conventional fluoride dentifrice (Signal Complete 8 Original, Unilever, Egypt), which has no documented desensitizing efficacy
The patients will be instructed to use 1 inch amount of the assigned desensitizing toothpaste and soft bristle toothbrushes with the same brushing technique they will be taught in the intervention visit for 2 minutes twice a day (morning and last thing at night ) without further rinsing, only spitting of the excess material every day along the whole study period for the continuous treatment group.
Degree of Dentin hypersensitivity
Visual analog scale (VAS)
Time frame: change from the baseline, 1month, 2months, 4 months, 6 months after treatment
Examiner Assessment to level of patient pain
Schiff sensitivity scale \[SSS\]
Time frame: change from the baseline, 1month, 2months, 4 months, 6 months after treatment
Patient satisfaction with the Treatment
4-point Likert scale
Time frame: change from the baseline, 1month, 2months, 4 months, 6 months after treatment
Plan to share: No
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This study is not yet recruiting, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
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Rawda Hesham Abd ElAziz