ClinicalTrials.gg
Sign In
RecruitingNCT07337109Updated Apr 28, 2026

A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers

An observational study in Dentin Hypersensitivity, sponsored by HALEON. Recruiting at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-28.

Sponsored by HALEON · Observational

From the registry’s dates

  • Started Dec 2025; still recruiting 10 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
375
Ages
18 Years and older
Sex
All
01

Study summary

The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.

Read the detailed description

This will be a longitudinal study investigating OHrQoL and treatment patterns amongst new sufferers of self-reported Dentin Hypersensitivity (DH). Over the 12-month study duration, 375 participants suffering from DH will complete questionnaires online once per month.

02

Conditions studied

  • Dentin Hypersensitivity

Browse trials for

03

In context

Dentin Sensitivity

288 studies on the registry are indexed under Dentin Sensitivity; 46 are open to participants now.

Browse Dentin Sensitivity studies →

Lead sponsor

HALEON is the lead sponsor of 64 studies on the registry; 9 are open to participants now.

Of its 6 completed or terminated interventional studies of FDA-regulated products, 2 (33%) have results posted.

Browse HALEON studies →

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Participants who are new sufferers of DH and have begun treating their DH.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Participant who has provided consent indicating they have been informed of all pertinent aspects of the study.
  • All genders who, at the time of screening, are aged more than or equal to (>=)18 years.
  • Anyone who has begun to experience dentin (self-reported) within the past three months.
  • Anyone who has started to use products to treat their tooth sensitivity within the past three months.
  • Participant who is able to independently complete all activities online.
  • Participants residing in the United States.

Exclusion criteria

Exclusion Criteria:

  • Anyone who has any chronic health conditions that could impact their participation in this study, such as cancer, mental health disorders, history of serious illness in the last three months, history of substance abuse, or planned surgery during the study period.

  • Participant whose sensitivity could be caused by other factors or clinical pathology than DH, as self-reported on the screening questionnaire, which include:

    1. Anyone who suffers from tooth cavities, significant gum disease, cracked or fractured teeth, temporomandibular joint disease (TMD), or who has had tooth extractions or fillings within the last three months.
    2. Anyone who wears braces (including Invisalign-like appliances) for treatment or dentures (full or partial).
    3. Participant who has undergone treatment for periodontal or gum disease within 6 months of screening or is currently undergoing treatment for periodontal or gum disease.
    4. Participant who has been informed by a Dental Health Care Professional (DHCP) that they have active periodontitis.
    5. Participant who has been informed by a DHCP that they have active caries.
    6. Participant with any chronic and/or severe painful health condition(s) which lead to regular use of pain relief medications (more than 3 days a week).
  • Anyone who has participated in another dentin study within the last three months.
  • Currently participating in another research study or will be participating in any other research study at any point during this study's duration.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Hypersensitivity

An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
375 participants (estimated)
Patient registry
No

Groups and cohorts

  • New sufferers of self-reported Dentin Hypersensitivity aged 18+ years
06

What researchers measure

Primary outcomes

  1. Change From Baseline in Total DHEQ Score Over 12 Months

    Change from baseline in total DHEQ score and each of the domain scores (daily restrictions, coping behaviors, personal identity, social impact, emotional impact) over 12 months. The DHEQ has total 15 questions each will be scored on a scale ranging from 1 (strongly disagree) to 7 (strongly agree), thus total possible score will be ranging from 15 to 105, where higher score indicates worst outcome.

    Time frame: Baseline and up to 12 Months

Secondary outcomes

  1. Description of Treatment Selection Over 12 Months

    Participants will select the appropriate options from the given list of products. Data will be summarized using descriptive statistics.

    Time frame: Up to 12 Months

  2. Treatment Discontinuation/Switch Over 12 Months

    Participant will respond to the question either as Yes or No. Data will be summarized using descriptive statistics.

    Time frame: Up to 12 Months

  3. Frequency of Treatment Used Over 12 Months

    Participants will select the appropriate frequency options from the given list. Data will be summarized using descriptive statistics.

    Time frame: Up to 12 Months

  4. Frequency of DH Over 12 Months

    Participants will select the appropriate frequency options from the given list. Data will be summarized using descriptive statistics.

    Time frame: Up to 12 Months

  5. Frequency of Brushing at Baseline, Months 6 and 12

    Participants will select the appropriate frequency options from the given list. Data will be summarized using descriptive statistics.

    Time frame: Baseline, Months 6 and 12

07

Study locations

1 of 1 sites recruiting
  • Citruslabs (Virtual Site)
    Las Vegas, Nevada 89118, United States
    Recruiting
    • Ellen O'Gormon, Dr · Contact
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Dec 2025 (actual). Primary completion is estimated for Feb 2027, 14 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 12, 2025
First posted
Jan 13, 2026
StartActual
Dec 16, 2025
Primary completionEst.
Feb 2027
CompletionEst.
Feb 2027
Last update
Apr 28, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 28, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07337109
Lead sponsor
HALEON
Responsible party
Sponsor
First posted
Jan 13, 2026
Start date
Dec 16, 2025
Primary completion
Feb 2027 (estimated)
Completion
Feb 2027 (estimated)
Last update
Apr 28, 2026

Study contacts

Haleon Response Center
Contact
ww.clinical-trial-register@haleon.com
+441932959500
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies in this condition

Dentin Sensitivity →

Other studies from this sponsor

HALEON →

Start the discussion