Drug
Sodium Fluoride clinical trials
Includes 1 study of Sodium fluoride topical preparation.
- studies test it
- 48
- open now
- 5
- in phase 3
- 15
- first study started
- 2003
Keep track of what changes. Save the Sodium Fluoride studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
48 studies that test it; most in 2023 (6)
| Year | Studies |
|---|---|
| 2003 | 2 |
| 2004 | 1 |
| 2007 | 1 |
| 2008 | 3 |
| 2009 | 3 |
| 2011 | 2 |
| 2012 | 1 |
| 2013 | 1 |
| 2014 | 4 |
| 2015 | 4 |
| 2016 | 3 |
| 2017 | 4 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 2 |
| 2023 | 6 |
| 2024 | 2 |
| 2025 | 6 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 2
- Phase 2
- 12
- Phase 3
- 15
- Phase 4
- 6
- No phase
- 12
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 15 · Other 33
GlaxoSmithKline (11) · Cairo University (5) · Colgate Palmolive (3) · University of Jazan (1) · Hue University of Medicine and Pharmacy (1) · Procter and Gamble (1) · Sacide Duman (1) · British University In Egypt (1)
Often tested with
Tested in the same studies.
Casein phosphopeptide-amorphous calcium phosphate nanocomplex (3) · Potassium nitrate (3) · Silver diamine fluoride (2) · Sodium Bicarbonate (2) · Cetylpyridinium (1) · Zinc lactate (1) · Gluma desensitizer (1) · Tenocyclidine (1)
Studies
Open first, then newest update. How each study uses Sodium Fluoride is read from its arms, and is right about nine times in ten.
Testing it · 48
- Comparative Efficacy of Laser Systems and Fluoride in Managing Dentinal Hypersensitivity: RCTNot yet recruitingNot applicableCairo UniversityNCT07141576Written as Fluoride varnish
- The Effect of Sodium Fluoride Application on the Prevention of Radiation Caries in NPC PatientsNot yet recruitingPhase 2Sun Yat-sen UniversityNCT06174012Written as Sodium Fluoride
- White Spot Lesions Treatment in OrthodonticNot yet recruitingPhase 4Riyadh Elm UniversityNCT06051981Written as 5% sodium fluoride
- Comparative Evaluation of Giomer Varnish vs Fluoride Varnish as Desensitizing Agents in Teeth With MIHNot yet recruitingPhase 3Cairo UniversityNCT05542667Written as Fluoride varnish
- Randomized Clinical Trial: Oral Health Package Law and Fluor Varnish Impact on Schoolchildren in Merida, MexicoRecruitingPhase 3Anahuac Mayab UniversityNCT05960110Written as Fluoride varnish
- Effect Of Three Remineralizing Agents On Early Childhood CariesCompletedPhase 2University of JazanNCT07371117Written as Sodium Fluoride with CPP-ACP
- Investigation of Clinical Efficacy of a New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems as Compared to a Control MouthwashCompletedPhase 3Colgate PalmoliveNCT07263698Written as cetylpyridinium chloride (CPC), zinc lactate and sodium fluoride Mouthwash
- Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.CompletedPhase 3Colgate PalmoliveNCT07398846Written as 0.022% Sodium Fluoride mouthwash
- Early Treatments for Preventing Occlusal Caries LesionsCompletedNot applicableHue University of Medicine and PharmacyNCT05969756Written as Fluoride varnish
- Assessing Gingivitis of 3 Different Dentifrices Compared to a Negative Control.CompletedPhase 2Procter and GambleNCT06892834Written as Sodium Fluoride Dentifrice
- "Comparison of the Effects of Resin Infiltrant, Fluoride Varnish, and the Combined Application of Resin Infiltrant and Fluoride Varnish on Primary Molars in the Treatment of Proximal Non-Cavitated Carious Lesions in Children."CompletedNot applicableSacide DumanNCT07112963Written as Fluoride Varnish
- Efficacy of Manual Toothbrushes in Removing Tooth StainsCompletedPhase 3Colgate PalmoliveNCT06486974Written as NaF
- Effect of Gluma and Bioactive Glass Desensitizers in Treatment of Dentin Hypersensitivity in Cervical Non-Carious LesionsCompletedNot applicableBritish University In EgyptNCT07063433Written as Fluoride varnish
- Comparative Effectiveness of Remineralization Agents on Attachment-Associated Demineralization in Clear Aligner PatientsCompletedNot applicableBezmialem Vakif UniversityNCT07229105Written as Sodium Fluoride varnish
- Intensive Preventative Dental Program Pilot StudyCompletedEarly Phase 1Wake Forest University Health SciencesNCT07218068Written as Fluoride varnish
- Cariostatic and Remineralizing Effects of Three Different Dental VarnishesCompletedPhase 4Nisreen Ibrahim khanNCT04887389Written as sodium Fluoride Varnish
- The Anticariogenic Effect of Silver Diamine Fluoride and Sodium Fluoride VarnishCompletedPhase 1Universiti Teknologi MaraNCT06316323Written as Sodium fluoride
- Effects of Three Different Mouth Rinses on Dental Plaque in ChildrenCompletedNot applicableSuez Canal UniversityNCT06013735Written as sodium fluoride solution
- Early Childhood Caries Prevention at a Pediatric ClinicCompletedNot applicableUniversity of Maryland, BaltimoreNCT00497029Written as fluoride varnish
- Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans ReductionTerminatedPhase 2Montefiore Medical CenterNCT02598778Written as Sodium Fluoride (0.05%)
See all 48 studies that test Sodium Fluoride →
Given in every arm · 5 — Sodium Fluoride is usual care beside what is tested
- Oral Hygiene Assistance Training ProgramNot yet recruitingPhase 4Colgate PalmoliveNCT07807397Written as sodium fluoride Mouthwash
- Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101CompletedPhase 1Colgate PalmoliveNCT06182267Written as Sodium Fluoride
- Medical Management of Caries in the Primary Dentition Using Silver NitrateCompletedEarly Phase 1Arwa OwaisNCT02604134Written as Fluoride varnish
- Evaluation of the Effect of Fluoride and Laser Application on the Prevention of Sensitivity in Bleached TeethCompletedPhase 1Universidade Federal do ParaNCT03044171Written as 1.1% Sodium Fluoride
- Enamel Remineralization Potential of Dentifrices in SituCompletedPhase 4GlaxoSmithKlineNCT01128946Written as NaF
As the comparator · 38 — what is tested is compared with Sodium Fluoride
- Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum ProblemsRecruitingPhase 3Colgate PalmoliveNCT07842991Written as 67% Bicarbonate with NaF (1400 F)
- Effect of an Experimental Cannabidiol Gel on Tooth SensitivityNot yet recruitingPhase 1Universidade Federal do ParaNCT07027566Written as Potassium nitrate and sodium fluoride
- Remineralization Effect Of Egg Shell Versus Fluoride Varnish On Early Carious White Spot Lesions In Primary TeethNot yet recruitingPhase 2Cairo UniversityNCT06932926Written as Fluoride varnish
- Preventive Effects of Silver Diamine Fluoride on Early Enamel CariesNot yet recruitingPhase 2National University of MalaysiaNCT06797882Written as Fluoride varnish
- The Remineralization of Early Enamel Caries in Permanent TeethNot yet recruitingPhase 1Tanta UniversityNCT06358066Written as 5% sodium fluoride varnish
- Comparison Between the Effect of Triclosan Toothpaste and Chlorhexidine Mouthwash on Gingival Health in a Group of Fixed Orthodontic Patients: A Randomized Controlled Clinical TrialCompletedPhase 4University of Science and Technology, YemenNCT07814898Written as sodium fluoride 0.24% toothpaste
- Stannous Fluoride Toothpaste for Reduction and Treatment of GingivitisCompletedNot applicableChurch & Dwight Company, Inc.NCT07640399Written as Sodium Fluoride Dentifrice
- Root Caries Prevention Using Fluoride Varnish Fortified With SBGCActive, not recruitingNot applicableThe University of Hong KongNCT06131957Written as Fluoride varnish
- A Clinical Study to Evaluate the Effectiveness of an Test Toothpaste for the Relief of Dentin Hypersensitivity in a Chinese PopulationCompletedNot applicableHALEONNCT07352956Written as Sodium fluoride toothpaste
- A Study to Evaluate the Effect of a Test (Sodium Bicarbonate) Toothpaste on the Oral MicrobiomeCompletedNot applicableHALEONNCT07273539Written as Sodium Fluoride Toothpaste
- Preventing Early Childhood Caries With a Silver Diamine Fluoride GelActive, not recruitingPhase 2The University of Hong KongNCT07455604Written as Sodium Fluoride varnish
- Evaluation of a Stannous Fluoride Dentifrice for Control of Oral MalodorCompletedNot applicableChurch & Dwight Company, Inc.NCT07425509Written as Sodium Fluoride Dentifrice
- Dental Plaque Prevention Efficacy of a Stannous Fluoride ToothpasteCompletedNot applicableChurch & Dwight Company, Inc.NCT07419737Written as Sodium Fluoride Dentifrice
- A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment MethodsCompletedPhase 4Procter and GambleNCT07211061Written as Sodium Fluoride Dentifrice
- Evaluation of Biomimetic Mineralization Plus Soft Laser Irradiation in Dentin Hypersensitivity ManagementCompletedNot applicableMTI UniversityNCT06829277Written as Sodium fluoride varnish
- A Clinical Study Investigating the Effects of a Dentifrice Containing 0.454% Stannous Fluoride on Gingivitis Treatment and Plaque Reduction When Used Twice Daily for 12 WeeksCompletedNot applicableHALEONNCT06143670Written as Sodium fluoride toothpaste
- Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary TeethCompletedEarly Phase 1Alexandria UniversityNCT06566833Written as 5% sodium fluoride varnish
- Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)CompletedNot applicableProcter and GambleNCT01549587Written as 0.243% sodium fluoride
- A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum ProblemsCompletedPhase 3Colgate PalmoliveNCT05821712Written as 0.057% sodium fluoride Mouthwash
- Arrest of Interproximal Caries Lesion With 38% Silver Diamine Fluoride SolutionCompletedPhase 3Postgraduate Institute of Dental Sciences RohtakNCT05791669Written as Sodium fluoride varnish
Showing 20 of 38.
Codes
What other systems call Sodium Fluoride · ClinicalTrials.gg INT008212
- MeSH (NLM) D012969Sodium FluorideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 8ZYQ1474W7SODIUM FLUORIDEConfirmed FDA, NLM, Wikidata
- RxNorm 9873Confirmed FDA, Wikidata
- Wikidata Q407520sodium fluorideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C832Sodium FluorideOne source FDA
- DrugBank DB09325One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D012969 | Sodium Fluoride | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 8ZYQ1474W7 | SODIUM FLUORIDE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 9873 | — | Confirmed FDA, Wikidata |
| Wikidata | Q407520 | sodium fluoride | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C832 | Sodium Fluoride | One source FDA |
| DrugBank | DB09325 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.