An interventional study of D Blue Diode Laser and ProSylc Bioactive Glass Powder in Non-Carious Cervical Lesions (NCCLs) and Dentin Hypersensitivity, sponsored by Cukurova University. Not yet recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-06-15.
Sponsored by Cukurova University · Not applicable, Interventional, and Treatment
The aim of this split-mouth clinical study is to compare the effectiveness of D Blue diode laser application and ProSylc bioactive glass powder application in reducing dentin hypersensitivity in patients with non-carious cervical lesions (NCCLs). Different treatment modalities will be applied within the same participant, and changes in dentin hypersensitivity will be evaluated following treatment. The primary outcome measure will be the reduction in dentin hypersensitivity after the interventions. The findings of this study are expected to contribute to the identification of effective non-invasive treatment approaches for the management of dentin hypersensitivity associated with non-carious cervical lesions.
This split-mouth clinical study was designed to compare the clinical effectiveness of two different non-invasive approaches used in the treatment of dentin hypersensitivity associated with non-carious cervical lesions (NCCLs). Dentin hypersensitivity is a common clinical condition characterized by a short, sharp pain arising from exposed dentin in response to thermal, evaporative, tactile, osmotic, or chemical stimuli. Non-carious cervical lesions play a significant role in the development of dentin hypersensitivity by exposing dentin surfaces to the oral environment.
In this study, the effectiveness of D Blue diode laser application and ProSylc bioactive glass powder application in reducing dentin hypersensitivity will be evaluated. The split-mouth study design will allow each participant to serve as their own control, thereby minimizing interindividual variability. Eligible teeth will be allocated to different treatment groups according to the study protocol, and all interventions will be performed following standardized clinical procedures.
The level of dentin hypersensitivity will be assessed before treatment and at predetermined follow-up intervals using standardized clinical evaluation methods. Based on the collected data, the effects of both treatment modalities on dentin hypersensitivity will be compared, and changes over time will be analyzed. In addition, the clinical applicability and patient tolerance of the interventions will be evaluated.
The findings of this study are expected to contribute to the existing literature regarding the effectiveness of non-invasive treatment methods for dentin hypersensitivity associated with non-carious cervical lesions and to provide evidence-based guidance for clinicians in selecting appropriate treatment approaches.
Participants who agree to participate in the study and sign the informed consent form
Exclusion Criteria:
Teeth assigned to this group will receive D Blue diode laser application for the management of dentin hypersensitivity associated with non-carious cervical lesions.
Device: D Blue Diode Laser
Teeth assigned to this group will receive ProSylc bioactive glass powder application for the management of dentin hypersensitivity associated with non-carious cervical lesions.
Device: ProSylc Bioactive Glass Powder
D Blue diode laser application for the treatment of dentin hypersensitivity associated with non-carious cervical lesions.
Also known as: Diode Laser
ProSylc bioactive glass powder application for the treatment of dentin hypersensitivity associated with non-carious cervical lesions.
Also known as: Bioactive Glass Powder
Change in Dentin Hypersensitivity
Dentin hypersensitivity will be assessed using a Visual Analog Scale (VAS) following standardized air stimulus application. The change in VAS scores from baseline to follow-up visits will be evaluated.
Time frame: Baseline, immediately after treatment, 1 week, 1 month, and 3 months
Plan to share: No
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Cukurova University