Wake Forest University Health Sciences: Cognitive Dysfunction trials

The registry lists 29 Cognitive Dysfunction studies with Wake Forest University Health Sciences as lead sponsor. 6 are open to participants now and 13 have results posted.

Phase 1 2Phase 2 8Phase 3 1Phase 4 1No phase 17(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's DiseaseNot yet recruitingNCT07756294Phase 2
• Comparing Two Acute Care Transition Programs for Older Adults and Their Family CaregiversRecruitingNCT07661355Not applicable
• The Better, Harder, Faster, Stronger StudyRecruitingNCT07220512
• Brain Structure and Clinical Endpoints in Myotonic Dystrophy Type 2Enrolling by invitationNCT05854433
• Wake Forest Alzheimer's Disease Clinical CoreRecruitingNCT03140865
• Biodistribution of [11C]PIB in Patients With Risk Factors for Alzheimer's DiseaseEnrolling by invitationNCT03089827
• A Portal-based Advance Care Planning Intervention Among Community-Dwelling Persons Living With Cognitive ImpairmentCompletedNCT06509373Not applicableResults posted
• SNIFF - Combo INI+EMPA TrialCompletedNCT05081219Phase 2Results posted
• A Telehealth Advance Care Planning Intervention in Those With Mild Cognitive Impairment or Unrecognized DementiaCompletedNCT04912245Not applicableResults posted
• SNIFF Multi-Device Study 2CompletedNCT04199767Phase 2Results posted
• Study of Nasal Insulin to Fight Forgetfulness - Device StudyCompletedNCT03857321Phase 2Results posted
• Testing Ramipril to Prevent Memory Loss in People With GlioblastomaCompletedNCT03475186Phase 2Results posted
• Brain Energy for Amyloid Transformation in Alzheimer's Disease StudyCompletedNCT03472664Not applicableResults posted
• Improvisational Movement for People With Memory Loss and Their CaregiversCompletedNCT03333837Not applicableResults posted
• COcoa Supplement and Multivitamin Outcomes Study for the MindCompletedNCT03035201Results posted
• Genomic Outcomes of MetforminCompletedNCT02986659Phase 4Results posted
• Phase 3 Randomized Placebo Controlled Clinical Trial of DonepezilCompletedNCT02822573Phase 3Results posted
• Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 120 Days (SL120)CompletedNCT01595646Phase 2Results posted
• Study of Donepezil in Female Breast Cancer Survivors With Cognitive DysfunctionCompletedNCT01466270Phase 2Results posted
• Anticipating Decline and Providing TherapyActive, not recruitingNCT06182995Not applicable
• SNIFF - 3-Week Aptar CPS DeviceWithdrawnNCT05006599Phase 2
• DHS MIND MetabolomicsCompletedNCT03975309
• U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce RiskCompletedNCT03688126Not applicable
• Cognitive Dysfunction and Breast Cancer Coping Strategies Impact on QOLCompletedNCT03476226Not applicable
• Biodistribution of [11C]Acetoacetate/[18F]Fluorodeoxyglucose in Subjects With Risk Factors for Alzheimer's DiseaseCompletedNCT03130036Not applicable
• Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's DiseaseCompletedNCT02984540Not applicable
• Macronutrient Effects on Alzheimer's Disease (MEAL-2)CompletedNCT02463084Not applicable
• Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin AspartCompletedNCT02462161Phase 1
• Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain TumorsCompletedNCT01151670Phase 1