Chemotherapy-Related Cognitive Impairment clinical trials

The registry lists 39 studies for Chemotherapy-Related Cognitive Impairment across more than 10 countries. 19 are recruiting or about to start. 17 of them are mainly about Chemotherapy-Related Cognitive Impairment (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-29.

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Status

Completed: 13
Recruiting: 10
Not yet recruiting: 7
Status unknown: 4
Enrolling by invitation: 2
Terminated: 2

Phase

Phase 2: 6
Phase 3: 2
Phase 1: 2
Phase 4: 1

Where

United States: 18
Spain: 3
China: 3
Austria: 1
Turkey: 1
France: 1

Who runs them

Vanderbilt University Medical Center (2) · The First Affiliated Hospital with Nanjing Medical University (2) · Institut Català d'Oncologia (1) · University of Pittsburgh (1) · Karolinska Institutet (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Mara Chambers (1) · Hospices Civils de Lyon (1)

What is being tested here

Drugs under test in Chemotherapy-Related Cognitive Impairment studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	All
Prebiotics	1	1
Butylphthalide	1	1
Acetylcysteine	1	1
Ashwagandha	1	1
Nicotine	0	1
Mesna	0	1
Doxorubicin	0	1
Dexmethylphenidate	0	1

Coming up

1phase 3 study under way

7studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 7, phase 3 first

Feb 2027Evaluating Cognitive Changes on Patients in Chemotherapy (ECCPC) · Phase 3 · Ellis Medicine
Nov 2026Cognitive Impairment in Treated Breast Cancer Survivors: Possible Approaches · Grigore T. Popa University of Medicine and Pharmacy
Dec 2026Impact of Supplementation With Synbiotics and Prebiotics on Cognitive Decline Associated With Neoadjuvant Chemotherapy in First-line Patients With Breast Cancer · Instituto Jalisciense de Cancerologia
Dec 2026Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT · University of California, Irvine
Dec 2026Cognitive Impairment in Patients With Diffuse Large B-Cell Lymphoma · Institute of Oncology Ljubljana
Mar 2027Investigating Cognitive Impairment in Young Patients With Cancer Prospectively · Rigshospitalet, Denmark
Nov 2027Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer · Karolinska Institutet

Who these studies take

Of the 10 Chemotherapy-Related Cognitive Impairment studies recruiting now, 6 (60%) set no upper age limit and 4 (40%) stop at 75 or younger. 2 (20%) take children under 18. 2 (20%) are for women only and 0 (0%) for men only; 4 (40%) take healthy volunteers.

Recruiting studies that take each age, of 10
Age	Women	Men
10	2 (20%)	2 (20%)
18	8 (80%)	7 (70%)
30	7 (70%)	6 (60%)
40	7 (70%)	6 (60%)
50	7 (70%)	6 (60%)
65	8 (80%)	6 (60%)
75	6 (60%)	4 (40%)
85	6 (60%)	4 (40%)

Across all 39 studies, recruiting or not: 44% stop at 75 or younger and 23% at 65; 8% take children; 41% are for women only and 0% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 39 of 39. search them.