Massachusetts General Hospital: Cognitive Dysfunction trials

The registry lists 33 Cognitive Dysfunction studies with Massachusetts General Hospital as lead sponsor. 13 are open to participants now and 8 have results posted.

Early Phase 1 1Phase 1 4Phase 2 6Phase 4 2No phase 23(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being Pilot RCTNot yet recruitingNCT07785648Not applicable
• AI-CONECT: A Conversational AI for Early Dementia Prevention in Socially-Isolated Older AdultsNot yet recruitingNCT07701668Not applicable
• Biomarker-based Trial of NPC-1 for Alzheimer's PathologyRecruitingNCT07236190Phase 2
• TMS for Cognitive Decline in Aging and Preclinical ADRecruitingNCT06956300Not applicable
• Cognitive Dysfunction in Chronic and Persistent Immune ThrombocytopeniaRecruitingNCT06817395
• Transcranial Magnetic Stimulation Treatment for Alzheimer's DiseaseRecruitingNCT06538311Early Phase 1
• Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive DeclineRecruitingNCT06246929Not applicable
• Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via InfliximabRecruitingNCT06136546Phase 2
• Sleep and Circadian Rhythm Biomarkers of Postoperative DeliriumRecruitingNCT06052397
• The Care for America's Aging StudyNot yet recruitingNCT06021704Not applicable
• Individual Closed-Loop Neuromodulation Therapy for Alzheimer's DiseaseRecruitingNCT05904132Not applicable
• Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical ADRecruitingNCT05881239
• Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverYRecruitingNCT04916210
• Mindfulness-based Cognitive Therapy for the Chronic Pain-early Cognitive Decline Co-morbidity Among Older Black Individuals in the Community; The Feeling of Being Open PilotCompletedNCT07210398Not applicableResults posted
• Effects Multimodal Mind and Body Approach for MCICompletedNCT06814483Phase 1Results posted
• Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket TrialCompletedNCT05189106Phase 1/2Results posted
• Managing Pain and Cognitions in Older Adults With Mild Cognitive Impairment or Memory Related Problems and Chronic PainCompletedNCT04044183Not applicableResults posted
• A Pilot of Methylphenidate in Mild Cognitive Impairment and Dementia Participants.CompletedNCT03811847Phase 4Results posted
• Internet-based Conversational Engagement Clinical TrialCompletedNCT02871921Not applicableResults posted
• Reversal of General Anesthesia With MethylphenidateCompletedNCT02051452Phase 1/2Results posted
• Memantine and Cognitive Dysfunction in Bipolar DisorderCompletedNCT00586066Phase 4Results posted
• Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia ConsortiumActive, not recruitingNCT06284213
• Psychosis TMS StudyActive, not recruitingNCT05857137Not applicable
• Managing Pain and Cognitions in Older Adults With Early Cognitive Decline and Chronic PainCompletedNCT05373745Not applicable
• Olfactory Deficits in Neurologic DiseaseCompletedNCT05019014
• My Healthy Brain: Preserving and Promoting Brain Health Through Evidence-based PracticesCompletedNCT04537728Not applicable
• TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and MemoryTerminatedNCT04294888Not applicable
• A Pilot Open Labeled Study of Tacrolimus in Alzheimer's Disease.WithdrawnNCT04263519Phase 2
• Modulation Effects of Baduanjin Exercise on Subjective Cognitive DeclineCompletedNCT04009382Not applicable
• Mental Training for Adults With Mild Cognitive ImpairmentCompletedNCT03895346Not applicable
• Gamma Induction for Alzheimer's DiseaseCompletedNCT03880240Phase 1/2
• Tau/P-Tau and Neurocognitive Outcomes in ChildrenStatus unknownNCT03511729
• Cognitive Deficits in Major Depressive Disorder and Bipolar Disorder, Depressed Type: Prevalence and Improvement With Treatment of Depressive SymptomsCompletedNCT00844974Not applicable