Cognition Disorders clinical trials
The registry lists 399 studies for Cognition Disorders across more than 10 countries. 74 are recruiting or about to start. 116 of them are mainly about Cognition Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 5 narrower conditions too, such as Cognitive Dysfunction: 4,733 studies, 1,287 open.
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Status
Who runs them
University of Southern California (6) · University Hospital, Angers (6) · University of Pittsburgh (5) · University of Washington (5) · Vanderbilt University Medical Center (4) · Charite University, Berlin, Germany (4) · National Institute on Aging (NIA) (4) · VA Office of Research and Development (4)
What is being tested here
Drugs under test in Cognition Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexmedetomidine | 1 | 1 | 4 |
| Minocycline | 1 | 0 | 3 |
| Memantine | 1 | 3 | 3 |
| Aripiprazole | 1 | 0 | 2 |
| Lacteol | 1 | 0 | 1 |
| Tributyrin | 1 | 0 | 1 |
| Prucalopride | 1 | 0 | 1 |
| Donanemab | 1 | 0 | 1 |
| Metformin | 1 | 0 | 1 |
| Gliclazide | 1 | 0 | 1 |
Drug classes tested here Antipsychotics 1 open · Cholinesterase inhibitors 10 · Stimulants 3 · Corticosteroids 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Cognitive Biomarkers in Pediatric Brain Tumor Patients · Washington University School of Medicine
- Dec 2026Supplementation of Inulin + L. Acidophilus in Elders With T2DM · Anahuac University
- Dec 2026Validation of the Lithuanian Version of the BNSS, CDSS, and the SCoRS · Lithuanian University of Health Sciences
- Dec 2026CBF and NCF Changes With Brain Radiation · University Health Network, Toronto
- Dec 2026Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study · Folktandvården Stockholms län AB
- Dec 2026Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation · Francisco Gonzalez-Lima, PhD
- Jan 2027Longitudinal Early-onset Alzheimer's Disease Study Protocol · Indiana University
- Jan 2027Impact of Anesthesia Alarm Volume on Mental Workload in Surgical Trainees · Institut de Cancérologie de Lorraine
- Feb 2027Brain Injury and Cognitive Function · Institut National de la Santé Et de la Recherche Médicale, France
- Mar 2027Monitoring Neurocognitive Dysfunction and the Impact of Metabolism and Physical Capacity After Paediatric HSCT · Rigshospitalet, Denmark
Who these studies take
Of the 47 Cognition Disorders studies recruiting now, 20 (43%) set no upper age limit and 12 (26%) stop at 75 or younger. 6 (13%) take children under 18. 1 (2%) are for women only and 1 (2%) for men only; 13 (28%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (13%) | 6 (13%) |
| 18 | 21 (45%) | 22 (47%) |
| 30 | 20 (43%) | 21 (45%) |
| 40 | 22 (47%) | 23 (49%) |
| 50 | 26 (55%) | 27 (57%) |
| 65 | 37 (79%) | 37 (79%) |
| 75 | 35 (74%) | 35 (74%) |
| 85 | 29 (62%) | 28 (60%) |
Across all 399 studies, recruiting or not: 38% stop at 75 or younger and 31% at 65; 11% take children; 3% are for women only and 3% for men only; 30% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cognition Disorders studies take
Of 92 interventional studies with no phase under Cognition Disorders, half reached primary completion within 34 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 34 mo15–55 · 92 studies | — | 34 mo16–55 · 87 studies |
| Observational | 41 mo13–89 · 44 studies | — | 41 mo13–89 · 43 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Westlake Aging Cohort (WeAC)Nov 6, 2026NCT07373444
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 399. Browse all 399 → or search them.
- Westlake Aging Cohort (WeAC)RecruitingNCT073734441 country
- A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)RecruitingNCT07589595Phase 24 countries
- Minocycline In Neurocognitive Outcomes - Sickle Cell DiseaseNot yet recruitingNCT05605366Phase 1
- Supplementation of Inulin + L. Acidophilus in Elders With T2DMNot yet recruitingNCT06830824Not applicable
- Ca-Mg Butyrate in Gulf War IllnessRecruitingNCT05367245Phase 21 country
- A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)Not yet recruitingNCT06792500Phase 1/21 country
- Alzheimer's Disease Neuroimaging Initiative 4Enrolling by invitationNCT056170142 countries
- Decoding Central Defects in Dystrophinopathies From Diagnostic to RemediationRecruitingNCT071258981 country
- Prucalopride for Cognitive Functioning in SchizophreniaNot yet recruitingNCT06474286Not applicable1 country
- Impact of Glasses for Vision Problems on Cognitive Function in Rural Older AdultsRecruitingNCT06836440Not applicable1 country
- Establishing Normal Cognitive Test Scores for Adults Using a Voice-Enabled Digital Testing Platform Across the LifespanRecruitingNCT077633921 country
- Interventions in Mathematics and Cognitive SkillsRecruitingNCT05201534Not applicable1 country
- Comparison of Accelerated Intermittent Theta Burst Stimulation vs High Frequency Transcranial Magnetic Stimulation (Hf-rTMS) on Cognitivesymptoms in Treatment-resistant SchizophreniaNot yet recruitingNCT07445620Not applicable1 country
- Prevalence of Mild Cognitive Impairment and Dementia in Patients Admitted to Non-neurological Rehabilitation WardsRecruitingNCT07731334Not applicable1 country
- Post-acute Infectious Syndrome - Aripiprazole Symptom Evaluation (PAIS-AriSE)Not yet recruitingNCT07714213Phase 21 country
- Home-Based Brain Stimulation for Motoric Cognitive Risk SyndromeRecruitingNCT06821568Not applicable2 countries
- Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast CancerRecruitingNCT02290834Not applicable1 country
- Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive DeclineRecruitingNCT06246929Not applicable1 country
- Personality Traits as a Variable in the Recovery of Patients With Acquired Brain InjuryRecruitingNCT071198271 country
- Neurocognitive Effects of Non-Invasive Near-Infrared Light StimulationRecruitingNCT05802680Not applicable1 country
- Moderate-Intensity Aerobic Calisthenics for Rural Elderly With Motoric Cognitive Risk SyndromeNot yet recruitingNCT07658469Not applicable1 country
- Efficacy and Mechanisms of TUS on Cognitive Deficits in Schizophrenia: Based on the Hippocampal-Prefrontal CircuitNot yet recruitingNCT06904092Not applicable1 country
- Brain Stimulation and Cognitive Training for MCIRecruitingNCT07526740Not applicable1 country
- The Effect of tDCS Combined With TMS on Cognitive Impairment and Motor Function After StrokeNot yet recruitingNCT07573475Not applicable1 country
- Dual-site Cross-frequency Coupled Transcranial Electrical Stimulation Modulates Working Memory of Patients With Post-stroke Cognitive ImpairmentNot yet recruitingNCT07573501Not applicable1 country
- Low-frequency Electrical Stimulation for Cognitive Enhancement in Atrial FibrillationEnrolling by invitationNCT07063381Not applicable1 country
- REPAIR Sleep StudyNot yet recruitingNCT07572565Not applicable
- Hyperbaric Oxygen Therapy for Post-COVID-19 SyndromeRecruitingNCT04647656Not applicable1 country
- Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health HospitalNot yet recruitingNCT07506070Not applicable
- MRI Technical Development and Applications in Kidney DiseaseNot yet recruitingNCT024214971 country
- Influence of Individual Traits on Adaptation Processes in Individuals With Alcohol Use DisorderNot yet recruitingNCT074688251 country
- Neurocognitive Deficit After Paediatric Transplantation: Understanding the Role of Environment and Physical FunctionNot yet recruitingNCT074087131 country
- Virtual-reality Exercises for Alleviating Attention Deficits in Patients With Acquired Brain InjuryRecruitingNCT05728840Not applicable1 country
- Microbiome-Targeted Enhancement of Neurocognition With Probiotics-Riboflavin CombinationNot yet recruitingNCT07410052Not applicable
- MEOP - Multidimensional Evaluations in Oncological PsychiatryNot yet recruitingNCT07406113
- LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.Not yet recruitingNCT07376135Not applicable1 country
- Patient-Centered NeuroRehabilitation (PCN)RecruitingNCT03036319Not applicable1 country
- Nutrition-based Interventions to Prevent Cognitive DeclineRecruitingNCT06853405Not applicable1 country
- Cognitive Functioning and Health Related Quality of Life in Retinoblastoma SurvivorsEnrolling by invitationNCT062279621 country
- Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery PatientsRecruitingNCT04289142Phase 41 country
- Effect of ExoBDNF Lactic Acid Bacteria Supplement on Cognitive Functions, Sleep and PsychologicalRecruitingNCT06968299Not applicable1 country
- Cognitive Biomarkers in Pediatric Brain Tumor PatientsRecruitingNCT02914067Not applicable1 country
- Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)RecruitingNCT06413173Not applicable1 country
- Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide RibosideRecruitingNCT052459031 country
- Early Severe Illness TrAnslational BioLogy InformaticS in HumansRecruitingNCT055919241 country
- Depth of Anesthesia on Postoperative Delirium and Cognitive After SurgeryRecruitingNCT06268080Not applicable1 country
- Monitoring Neurocognitive Dysfunction and the Impact of Metabolism and Physical Capacity After Paediatric HSCTNot yet recruitingNCT071404451 country
- Neuromodulation and Attention Deficits in MDDRecruitingNCT07111169Not applicable1 country
- VIrtual Reality Glasses Use to Improve Lateropulsion and the Post-stroke Postural VerticalRecruitingNCT04911738Not applicable1 country
- Evaluation of Memantine in the Preservation of Memory and Neurocognition Following CSIRecruitingNCT06275035Phase 31 country