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Cocaine-Related Disorders clinical trials

The registry lists 416 studies for Cocaine-Related Disorders across more than 10 countries. 12 are recruiting or about to start. 367 of them are mainly about Cocaine-Related Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.

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Status

Completed
328
Status unknown
35
Terminated
26
Withdrawn
12
Recruiting
11
Active, not recruiting
2

Phase

Phase 2
199
Phase 1
92
Phase 3
25
Phase 4
16
Early Phase 1
10

Where

United States
365
Brazil
11
France
7
Spain
5
Switzerland
5
Mexico
3

Who runs them

National Institute on Drug Abuse (NIDA) (105) · Yale University (41) · New York State Psychiatric Institute (32) · University of Pennsylvania (24) · Medical University of South Carolina (18) · The University of Texas Health Science Center, Houston (16) · Baylor College of Medicine (13) · Johns Hopkins University (9)

What is being tested here

Drugs under test in Cocaine-Related Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Ketamine103
Semaglutide101
Modafinil0120
Cocaine0015
Dextroamphetamine0012
Naltrexone0311
Disulfiram0011
Risperidone0010
Buprenorphine039
Acetylcysteine009

Drug classes tested here Stimulants 48 · Antipsychotics 23 · Local anesthetics 16 · Opioid antagonists 12 · Opioids 12

Coming up

0phase 3 studies under way
3studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 3

Who these studies take

Of the 11 Cocaine-Related Disorders studies recruiting now, 5 (45%) set no upper age limit and 6 (55%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 11
AgeWomenMen
100 (0%)0 (0%)
189 (82%)9 (82%)
3011 (100%)11 (100%)
4011 (100%)11 (100%)
5011 (100%)11 (100%)
657 (64%)7 (64%)
755 (45%)5 (45%)
855 (45%)5 (45%)

Across all 416 studies, recruiting or not: 83% stop at 75 or younger and 80% at 65; 3% take children; 3% are for women only and 7% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Cocaine-Related Disorders studies take

Of 22 phase 2 interventional studies under Cocaine-Related Disorders, half reached primary completion within 35 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 131 mo14–53 · 14 studies——
Phase 235 mo23–51 · 22 studies——
Interventional, no phase29 mo25–50 · 23 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 416. Browse all 416 → or search them.