Drug
Cocaine clinical trials
- studies test it
- 35
- open now
- 1
- in phase 3
- 3
- first study started
- 1995
Keep track of what changes. Save the Cocaine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
34 studies that test it; most in 2015 (5)
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1996 | 2 |
| 1997 | 1 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 1 |
| 2009 | 1 |
| 2012 | 4 |
| 2013 | 1 |
| 2014 | 4 |
| 2015 | 5 |
| 2016 | 3 |
| 2018 | 2 |
| 2019 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 1 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 7
- Phase 1
- 18
- Phase 2
- 3
- Phase 3
- 3
- Phase 4
- 3
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 6 · Other 29
National Institute on Drug Abuse (NIDA) (7) · Yale University (4) · Joshua A. Lile, Ph.D. (3) · Pharmaceutical Project Solutions, Inc. (3) · William Stoops (3) · New York State Psychiatric Institute (3) · University of Texas Southwestern Medical Center (2) · Lannett Company, Inc. (2)
Often tested with
Tested in the same studies.
Mavoglurant (1) · Clavulanic Acid (1) · Nicotine (1) · Methylphenidate (1) · Quinine (1) · Acetazolamide (1) · Aripiprazole (1) · Epinephrine (1)
Studies
Open first, then newest update. How each study uses Cocaine is read from its arms, and is right about nine times in ten.
Testing it · 35
- Cocaine and Pentoxifylline (BED IN 47)RecruitingEarly Phase 1William StoopsNCT07086794Written as Cocaine (IV)
- Phase1, STP7 Cocaine Drug-Drug Interaction StudyCompletedPhase 1Stalicla SANCT06273540Written as Cocaine Hydrochloride
- Intranasal Cocaine and Temperature Regulation During ExerciseCompletedPhase 1/2University of Texas Southwestern Medical CenterNCT05809453Written as Cocaine
- Neurobehavioral Mechanisms of Cocaine ChoiceCompletedEarly Phase 1Joshua A. Lile, Ph.D.NCT04296006Written as Cocaine HCl
- Behavioral Effects of Drugs (Inpatient): 38TerminatedEarly Phase 1William StoopsNCT03954938Written as Cocaine
- Investigation of Cocaine Addiction Using mGluR5 PET and fMRICompletedPhase 1Yale UniversityNCT03471182Written as Cocaine Self-adminstration
- Clavulanic Acid (CLAV) and Cocaine Interaction Safety StudyCompletedPhase 1Temple UniversityNCT02563769Written as Intravenous cocaine
- Xylometazoline and Cocaine for Nasal VasoconstrictionCompletedPhase 4Rigshospitalet, DenmarkNCT05334017Written as Cocaine 4%
- Impulsivity and Stimulant AdministrationCompletedPhase 1Yale UniversityNCT01978431Written as cocaine hydrochloride
- Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in HumansCompletedPhase 1Yale UniversityNCT02018263Written as Cocaine hydrochloride
- Complementary Combination Therapy for Cocaine DependenceCompletedPhase 1Baylor College of MedicineNCT02538744Written as cocaine
- Drug Interaction and Self Administration Studies of Compounds for Cocaine Use DisorderCompletedPhase 1Virginia Commonwealth UniversityNCT02537873Written as Cocaine Intravenous (IV)
- Establishing and Eliminating Cue-drug Associations in Human Cocaine AddictionTerminatedPhase 1Yale UniversityNCT01978457Written as cocaine hydrochloride
- Behavioral Effects of Drugs: Inpatient (35)CompletedEarly Phase 1Craig RushNCT03519022Written as Cocaine
- Impact of a Non-Drug Choice on Cocaine ReinforcementCompletedEarly Phase 1Joshua A. Lile, Ph.D.NCT01906346Written as Cocaine
- Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug ReinforcerCompletedEarly Phase 1Joshua A. Lile, Ph.D.NCT02383043Written as Cocaine
- Study to Improve Scientific Understanding of the Cardiovascular Actions of CocaineWithdrawnPhase 1University of Texas Southwestern Medical CenterNCT00338546Written as Cocaine hydrochloride
- Pharmacokinetic Study of Intranasal RX0041-002 in Hepatic-Impaired Individuals and Subjects With Normal Hepatic FunctionCompletedPhase 1Pharmaceutical Project Solutions, Inc.NCT02775981Written as RX0041-002
- Interactions Between Intravenous Cocaine and Acetazolamide or QuinineCompletedPhase 1National Institute on Drug Abuse (NIDA)NCT01851473Written as cocaine
- PK Study of Intranasal RX0041-002 in Subjects With Severe Renal Impairment and Normal Renal FunctionCompletedPhase 1Pharmaceutical Project Solutions, Inc.NCT02775955Written as RX0041
See all 35 studies that test Cocaine →
Given in every arm · 12 — Cocaine is usual care beside what is tested
- Cocaine and ZolmitriptanCompletedEarly Phase 1William StoopsNCT05019430Written as Cocaine
- GLP-1 Agonism for Blocking Cocaine Euphoria and Self-AdministrationCompletedPhase 1Yale UniversityNCT02302976Written as cocaine hydrochloride
- Suvorexant and CocaineCompletedEarly Phase 1William StoopsNCT03937986Written as Cocaine
- Dexmedetomidine for Reversal of Cocaine's Effects on the HeartCompletedEarly Phase 1Cedars-Sinai Medical CenterNCT01927640Written as Intranasal cocaine
- Topiramate-Phentermine Combinations for Cocaine DependenceCompletedPhase 1University of KentuckyNCT02239913Written as Cocaine
- Reinforcing Effects of Cocaine During Phendimetrazine MaintenanceCompletedPhase 1William StoopsNCT02522325Written as Cocaine
- Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent VolunteersCompletedPhase 1/2Biotie Therapies Inc.NCT00656357Written as Cocaine 10mg
- Modafinil for Smoked Cocaine Self-AdministrationCompletedPhase 2New York State Psychiatric InstituteNCT01778010Written as Cocaine 0 mg
- Effect of Zonisamide on Cocaine Reinforcement, Craving, and RelapseCompletedPhase 1/2Johns Hopkins UniversityNCT01137890Written as Cocaine Hydrochloride
- A Study of Metyrapone and Oxazepam Combination Product (EMB-001) and CocaineCompletedPhase 1Embera NeuroTherapeutics, Inc.NCT02856854Written as Cocaine IV
- n-Acetylcysteine and CocaineCompletedEarly Phase 1University of KentuckyNCT02141620Written as Cocaine
- A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine AbuseCompletedPhase 2Indivior Inc.NCT01846481Written as Cocaine
Codes
What other systems call Cocaine · ClinicalTrials.gg INT007244
- MeSH (NLM) D003042CocaineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) I5Y540LHVRCOCAINEConfirmed FDA, NLM, Wikidata
- RxNorm 2653Confirmed FDA, Wikidata
- Wikidata Q41576cocaineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C80153CocaineOne source FDA
- DrugBank DB00907One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D003042 | Cocaine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | I5Y540LHVR | COCAINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2653 | — | Confirmed FDA, Wikidata |
| Wikidata | Q41576 | cocaine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C80153 | Cocaine | One source FDA |
| DrugBank | DB00907 | — | One source Wikidata |
Also registered as cocaine hydrochloride (UNII XH8T8T6WZH · RxNorm 81985).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.