Yale University: Cocaine-Related Disorders trials

The registry lists 40 Cocaine-Related Disorders studies with Yale University as lead sponsor. 0 are open to participants now and 16 have results posted.

Early Phase 1 2Phase 1 12Phase 2 13Phase 3 2No phase 12(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• The Role of Neuroactive Steroids in Stress, Drug Craving and Drug Use in Cocaine Use DisordersCompletedNCT03953612Early Phase 1Results posted
• Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo Using 11UCB-J PETCompletedNCT03527485Not applicableResults posted
• Investigation of Cocaine Addiction Using mGluR5 PET and fMRICompletedNCT03471182Phase 1Results posted
• Understanding Dopamine Mechanisms in Cocaine Addiction Using AMPT and Methylphenidate With [11C]RAC/[11C]PHNO PETTerminatedNCT02152670Not applicableResults posted
• A Drug Treatment for Cocaine Users Who Are Also on Methadone Maintenance TreatmentTerminatedNCT01802515Not applicableResults posted
• Progesterone for Postpartum Cocaine RelapseCompletedNCT01249274Not applicableResults posted
• Modafinil, Sleep Architecture and Cocaine RelapseCompletedNCT01137396Phase 2Results posted
• Pharmacotherapy & CM for Opioid and Cocaine DependenceCompletedNCT00838981Phase 1/2Results posted
• Galantamine to Enhance Cognitive Behavioral Therapy for Cocaine AbuseCompletedNCT00809835Phase 2Results posted
• Galantamine Effects on Cognitive Function in Abstinent Cocaine UsersCompletedNCT00606801Not applicableResults posted
• Modafinil, Sleep, and Cognition in Cocaine DependenceCompletedNCT00582491Not applicableResults posted
• Efficacy of Levetiracetam in Cocaine-Abusing Methadone Maintained PatientsCompletedNCT00577005Phase 2Results posted
• Efficacy of Varenicline in Methadone-Stabilized Cocaine UsersCompletedNCT00567320Not applicableResults posted
• Cocaine Withdrawal and Pharmacotherapy ResponseCompletedNCT00566969Not applicableResults posted
• CBT With Disulfiram and Contingency ManagementCompletedNCT00350870Phase 1Results posted
• Therapeutic Substance Abuse Treatment in Pregnancy - 1CompletedNCT00227903Phase 2Results posted
• Functional Magnetic Resonance Imaging of N-acetylcysteine in Cocaine DependenceCompletedNCT02994875Early Phase 1
• GLP-1 Agonism for Blocking Cocaine Euphoria and Self-AdministrationCompletedNCT02302976Phase 1
• PET Imaging in Cocaine Self AdministrationCompletedNCT02181491Not applicable
• Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRSCompletedNCT02124941Phase 1
• Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in HumansCompletedNCT02018263Phase 1
• Establishing and Eliminating Cue-drug Associations in Human Cocaine AddictionTerminatedNCT01978457Phase 1
• Impulsivity and Stimulant AdministrationCompletedNCT01978431Phase 1
• FMRI of Stress and Addictive DisordersCompletedNCT01558973
• Abstinence-Linked Money Management MultisiteCompletedNCT01327586Phase 2
• Behavioral Treatment for Cocaine Dependent WomenCompletedNCT00914381Phase 2
• Disulfiram for Cocaine Abuse in Buprenorphine TreatmentCompletedNCT00913484Phase 2
• Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients.CompletedNCT00593125Phase 2
• Sex Differences in Progesterone Effects on Responses to Stress and Drug CuesCompletedNCT00585520Phase 1
• Clinical Efficacy of Disulfiram in LAAM-Maintained Cocaine AbusersCompletedNCT00580827Not applicable
• Computer-Based Training in Cognitive Behavior TherapyCompletedNCT00350610Phase 1
• The Effects of GABA Enhancing Medications on Individuals Addicted to Cocaine - 3TerminatedNCT00142883Not applicable
• Combining Behavioral Treatment With Agonist Maintenance - 1CompletedNCT00000311Phase 3
• Pemoline for Cocaine Abuse - 7CompletedNCT00000282Phase 2
• Pharmacotherapy for Schizophrenic Drug Users - 6CompletedNCT00000281Phase 2
• Glutaminergic Agents for Cocaine Abuse - 5CompletedNCT00000280Phase 1
• Disulfiram for Cocaine-Alcohol Abuse - 3CompletedNCT00000278Phase 2
• Mazindol for Cocaine Abuse - 2CompletedNCT00000277Phase 2
• Dopamine Reuptake Inhibitors of Cocaine Abuse - 1TerminatedNCT00000276Phase 1
• Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1CompletedNCT00000216Phase 3