Drug
Disulfiram clinical trials
Also written Antabuse.
- studies test it
- 52
- open now
- 9
- in phase 3
- 2
- first study started
- 1994
Keep track of what changes. Save the Disulfiram studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
- Antabuse
- 19
Studies by the year they started
49 studies that test it; most in 2017 (4); 2 more planned to start later
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1999 | 1 |
| 2000 | 2 |
| 2001 | 1 |
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 3 |
| 2007 | 2 |
| 2008 | 3 |
| 2009 | 2 |
| 2010 | 1 |
| 2011 | 1 |
| 2013 | 1 |
| 2014 | 1 |
| 2016 | 2 |
| 2017 | 4 |
| 2018 | 2 |
| 2019 | 3 |
| 2020 | 3 |
| 2021 | 3 |
| 2023 | 2 |
| 2025 | 2 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 19
- Phase 2
- 29
- Phase 3
- 2
- Phase 4
- 5
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 50
Yale University (4) · University of California, San Francisco (4) · University of Arkansas (3) · National Cancer Institute, Slovakia (2) · Baylor College of Medicine (2) · Sahlgrenska University Hospital (2) · University of Utah (2) · Case Comprehensive Cancer Center (2)
Often tested with
Tested in the same studies.
Gluconates (7) · Copper (4) · Temozolomide (2) · Cisplatin (2) · Lorazepam (1) · Naltrexone (1) · Efavirenz (1) · Atazanavir (1)
Studies
Open first, then newest update. How each study uses Disulfiram is read from its arms, and is right about nine times in ten.
Testing it · 52
- MINTER Trial: Metal Intervention aNd ThErapy With Radiotherapy In Thoracic Cancer Using Copper Donor Therapy: A Phase 2, Open-Label StudyNot yet recruitingPhase 2M.D. Anderson Cancer CenterNCT07843537Written as Disulfiram 250 mg
- The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal DegenerationRecruitingPhase 1University of RochesterNCT06319872Written as Oral disulfiram
- Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory SarcomasRecruitingPhase 1Case Comprehensive Cancer CenterNCT05210374Written as Disulfiram
- Disulfiram in Rheumatoid ArthritisNot yet recruitingPhase 2University of OklahomaNCT07534332Written as Disulfiram (DSF)
- Disulfiram for Treatment of Retinal DegenerationRecruitingPhase 1/2University of WashingtonNCT05626920Written as Disulfiram 250 mg
- A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With OsteosarcomaRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT07477457Written as Disulfiram
- Anxiety During Abstinence in AUDRecruitingEarly Phase 1Columbia UniversityNCT06793488Written as Disulfiram 250 mg
- Disulfiram/Copper Combination In The Treatment of Newly Diagnosed Glioblastoma MultiformNot yet recruitingPhase 2Olympion Medical CenterNCT01777919Written as Disulfiram
- Treatment of Advance Gastric Cancer With DisulfiramNot yet recruitingNot applicableFirst People's Hospital of HangzhouNCT05667415Written as disulfiram and cisplatin
- Study of Disulfiram to Reduce Myeloid Immunosuppression and Steroid Dependence in Resectable High Grade GliomaSuspendedPhase 1Case Comprehensive Cancer CenterNCT07719127Written as Disulfiram (DSF)
- Phase II Trial of Disulfiram With Copper in Metastatic Breast CancerCompletedPhase 2The Institute of Molecular and Translational Medicine, Czech RepublicNCT03323346Written as Disulfiram
- Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed GlioblastomaCompletedPhase 1/2Washington University School of MedicineNCT02715609Written as Disulfiram
- Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme DiseaseCompletedPhase 1/2Research Foundation for Mental Hygiene, Inc.NCT03891667Written as Disulfiram
- Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma MultiformeTerminatedPhase 2Wake Forest University Health SciencesNCT03363659Written as Disulfiram
- Disulfiram-Copper Gluconate in Met Pancreas Cancer w Rising CA19-9 on Abraxane-Gemzar, FOLFIRINOX or GemcitabineTerminatedPhase 2HonorHealth Research InstituteNCT03714555Written as FOLFIRINOX regimen Plus Disulfiram/Copper Gluconate
- Vinorelbine, Cisplatin, Disulfiram and Copper in CTC_EMT Positive Refractory Metastatic Breast Cancer.WithdrawnPhase 2National Cancer Institute, SlovakiaNCT04265274Written as Disulfiram
- Disulfiram and Cisplatin in Refractory TGCTs.CompletedPhase 2National Cancer Institute, SlovakiaNCT03950830Written as Disulfiram
- DISulfiram for COvid-19 (DISCO) TrialTerminatedPhase 2University of California, San FranciscoNCT04485130Written as Disulfiram
- Disulfiram Combined With Lorazepam for Alcohol Dependence and Anxiety DisorderCompletedPhase 4University of New MexicoNCT00721526Written as disulfiram plus lorazepam
- A Study of the Relationship Between Disulfiram and Cocaine Self-administration.CompletedPhase 1/2Baylor College of MedicineNCT00729300Written as disulfiram
See all 52 studies that test Disulfiram →
Given in every arm · 3 — Disulfiram is usual care beside what is tested
- Disulfiram and Chemotherapy in Treating Patients With Refractory Solid Tumors or Metastatic Pancreatic CancerTerminatedPhase 1Mayo ClinicNCT02671890Written as Disulfiram
- A Proof-of-concept Clinical Trial Assessing the Safety of the Coordinated Undermining of Survival Paths by 9 Repurposed Drugs Combined With Metronomic Temozolomide (CUSP9v3 Treatment Protocol) for Recurrent GlioblastomaCompletedPhase 1/2University of UlmNCT02770378Written as Disulfiram
- Disulfiram in Treating Patients With Glioblastoma Multiforme After Radiation Therapy With TemozolomideCompletedEarly Phase 1Washington University School of MedicineNCT01907165Written as Disulfiram
Codes
What other systems call Disulfiram · ClinicalTrials.gg INT007386
- MeSH (NLM) D004221DisulfiramConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) TR3MLJ1UAIDISULFIRAMConfirmed FDA, NLM, Wikidata
- RxNorm 3554Confirmed FDA, Wikidata
- Wikidata Q409665disulfiramConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C447DisulfiramOne source FDA
- DrugBank DB00822One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004221 | Disulfiram | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | TR3MLJ1UAI | DISULFIRAM | Confirmed FDA, NLM, Wikidata |
| RxNorm | 3554 | — | Confirmed FDA, Wikidata |
| Wikidata | Q409665 | disulfiram | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C447 | Disulfiram | One source FDA |
| DrugBank | DB00822 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.